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Flashcards in Test Questions Deck (14):
1

Dihydropyridines focus on what?

Vascular selectivity (only work on vascular calcium channels)

2

What drug is both cardiac and vascular selective?

Diltiazem

3

Which drug is only cardiac selective?

Verapamil

4

Contraindication of DHP

Acute events, like angina and no forward flow.

5

What is an effect of K+ sparring diuretic? (test)

Blood K+ can become a little elevated, some cases its an advantage.

6

(test) what are 2 main markers of diuretic function?

Urea and Creatine. esp serum creatine

7

There is impaired glucose tolerance esp with ______

Thizides. Typically little more in diabetics

8

(test) Diuretic resistance generally happens with _______

repeated doses

9

(test) What 4 things does pK involve?

1. Absorption 2. Distribution (how it goes through the body) 3. Metabolism (How body uses/gets rid of it) 4. Elimination (How body removes completely)

10

Syncope reduces what?

pre and afterload

11

Nitrate _____ period required with long acting therapies

free. b/c if body is exposed to drug for long periods it builds a tolerance. Encouraged for patients

12

No cGMP equals what?

No vasodilation

13

Nitrate tolerance can also be related to free radical production explain more:

Reactive oxygen species (ros)- Are byproducts w/ these byproducts it can impair nitrate function.

14

reactive oxygen species ROS can do what?

are byproducts that can impair nitrate function