Flashcards in Test Questions Deck (14):
Dihydropyridines focus on what?
Vascular selectivity (only work on vascular calcium channels)
What drug is both cardiac and vascular selective?
Which drug is only cardiac selective?
Contraindication of DHP
Acute events, like angina and no forward flow.
What is an effect of K+ sparring diuretic? (test)
Blood K+ can become a little elevated, some cases its an advantage.
(test) what are 2 main markers of diuretic function?
Urea and Creatine. esp serum creatine
There is impaired glucose tolerance esp with ______
Thizides. Typically little more in diabetics
(test) Diuretic resistance generally happens with _______
(test) What 4 things does pK involve?
1. Absorption 2. Distribution (how it goes through the body) 3. Metabolism (How body uses/gets rid of it) 4. Elimination (How body removes completely)
Syncope reduces what?
pre and afterload
Nitrate _____ period required with long acting therapies
free. b/c if body is exposed to drug for long periods it builds a tolerance. Encouraged for patients
No cGMP equals what?
Nitrate tolerance can also be related to free radical production explain more:
Reactive oxygen species (ros)- Are byproducts w/ these byproducts it can impair nitrate function.