Tetanus POPS1

Question 1

active v. passive immunity and examples

Answer 1

active immunity is when you give something that illicit an immune response and memory. examples are toxoid injection. passive is when you just give the patient what it needs antibody wise - rapid response and short term - give immunoglobin

Question 2

primary and secondary response in terms of time/magnitiude

Answer 2

secondary is faster and longer acting and usually more potent

Question 3

immunogenicity

Answer 3

it can bind to a b cell and trigger a response

Question 4

toxicity

Answer 4

how toxic something can be…

Question 5

antigenic

Answer 5

can bind to a B cell and may or may not produce a response

Question 6

toxin

Answer 6

KILL! unattenuated version

Question 7

toxoid

Answer 7

active immunity. all create an immune response / make ab / memory —- slow, long lasting lasts 5-10 years

Question 8

tetanus immunoglobin

Answer 8

rapid, short term – passive immunity. gives ab to fight immediately. last like 3 weeks

Question 9

anti serum (human)

Answer 9

passive immunity/aquired

Question 10

anti serum (equine)

Answer 10

passive/ aquired

Question 11

serum sickness

Answer 11

caused by the deposition of circulating immune complexes within the organs and tissues (walls of BV) - usually if you give equine anti toxin twice.

Question 12

anaphylaxis

Answer 12

allergic rxn, IgE, mast cells

Question 13

how to do you give inj of toxoid and ig/antitoxin?

Answer 13

in two separate injections in distant sites

Question 14

“heterologous”

Answer 14

made in different species

Question 15

“homologous”

Answer 15

made in same species

Question 16

anti sera is _____ and ____ immunity

Answer 16

passive/aquired and antibody mediated

Question 17

toxoid is ____ and ____ immunity

Answer 17

active/aquired and antibody mediated

Question 18

all firefighters have had…

Answer 18

tetanus toxiod. don’t give IG but maybe give booster

Question 19

what about baby and tetanus?

Answer 19

you have to give human Ig because the baby still has mom’s IgG - and won’t be able to make their own ab for a long time

Question 20

boosters kick in adequately in ______ (time)

Answer 20

3-5 days

Question 21

previous tetanus is unlike other infectious diseases in that —

Answer 21

it won’t stimulate the immune system

Question 22

active immunization after exposure to an infectious disease should be done (v. passive) IF…

Answer 22

the incubation period of the dieases exceeds the time that is required to produce immunity. (so if the disease doesn’t kick in and you have time to produce active immunity - then do that… if not - and it kicks in fast and no time for active response then give Ig)

Question 23

toxoid is an effector inducer of active immunity when….

Answer 23

it is NOT toxic but it is the attenuated version which is immunogenic and antigenic