Texas Wesleyan Drug Reference Dosages

Question 1

Diazepam (Valium)
Dose - IV & PO
Onset
Duration

Benzodiazepine

Answer 1

Dose:
IV: 0.1 mg/kg;
PO: 0.2 mg/kg
Onset:
1-5 mins
Duration:
2-6hrs

Question 2

Lorazepam (Ativan)
Dose
Onset
Duration

Benzodiazepine

Answer 2

Dose:
IV: 0.04 mg/kg
PACU: 1-4 mg
Onset:
1-5 min
Duration:
6-10hrs

Question 3

Midazolam (Versed)
Dose
Onset
Duration

Benzodiazepine

Answer 3

Dose:
1-5 mg
Onset:
1-5 min
Duration:
15-80 min (1-2 hours)

Question 4

Flumazenil (Romazicon)
Dose
Onset
Duration

Benzodiazepine Reversal

Answer 4

Dose:
0.2 mg followed by 0.1 mg q min until 1 mg
MAX is 3 mg
Onset:
1-5 min
Duration:
30-60 min

Question 5

Droperidol (Inapsine)
Dose
Onset
Duration

Antiemetic - Dopamine (D2) Antagonist

Answer 5

Dose:
IV: 0.625-1.25 mg
Onset:
1-5 min
Duration:
2-3 hrs

Question 6

Promethazine (Phenergan)
Dose
Onset
Duration

Antiemetic - Histamine (H1) & Dopamine (D1) Antagonist

Answer 6

Dose:
IV: 6.25-25 mg
Onset:
1-5 min
Duration:
4-6 hrs

Question 7

Ondansetron (Zofran)
Dose
Onset
Duration

Antiemetic - Serotonin (5HT3) Antagonist

Answer 7

Dose:
IV: 4 mg
Onset:
10 min
Duration:
4-9 hrs

Question 8

Dexamethasone (Decadron)
Dose
Onset
Duration

Antiemetic - Corticosteroid

Answer 8

Dose:
IV: 4 mg
Onset:
10-30 min
Lecture said delayed onset of 2 hrs
Duration:
2-10 hrs

Question 9

Metoclopramide (Reglan)
Dose
Onset
Duration

Antiemetic - Dopamine (D1) Antagonist

Answer 9

Dose:
IV: 10-20 mg
Onset:
10 min
Duration:
2 hrs

Question 10

Scopolamine (Scopace & Maldemar)
Dose
Onset
Duration

Antiemetic - Anticholinergic (M1-ACh)

Answer 10

Dose:
140 mcg initially followed by 1.5 mg slowly over time
Onset:
2-4hrs
Duration:
72hrs

Question 11

Propofol (Diprivan)
Antiemetic Dose

Antiemetic - GABA Agonist

Answer 11

Dose:
IV: 10-20 mg followed by 10mcg/kg/min PRN

Question 12

Propofol (Diprivan)
Induction Dose
Onset
Duration

Induction Agent - GABA Agonist

Answer 12

Dose:
1.5-2.5 mg/kg
Onset:
30-60 sec
Duration:
1-8 min

Question 13

Etomidate (Amidate)
Dose
Onset
Duration

Induction Agent - GABA Agonist

Answer 13

Dose:
IV: 0.3 mg/kg
Onset:
1 min
Duration:
3-5 min

Question 14

Ketamine (Ketalar)
Induction, Analgesia, IM Dose
Onset
Duration

Induction Agent - NMDA Antagonist

Answer 14

Dose:
Induction: 0.5-1.5 mg/kg
Analgesia: 0.2-0.5 mg/kg
IM: 4-8 mg/kg
Onset:
1 min
Duration:
10-20 min

Question 15

Midazolam
Induction Dose
Onset
Duration

Induction Agent - Benzodiazepine

Answer 15

Dose:
IV: 0.1-0.2 mg/kg
w/ fentanyl 50-100 mcg first
Onset:
30-60 sec
Duration:
5-10 min

Question 16

Morphine (MS-Contin)
Dose
Onset
Duration

Opioid Agonist - Mu1 & Mu2

Answer 16

Dose:
Intra op IV: 1-10 mg
Post op IV: 5-20 mg
Onset:
10-20 min
Duration:
4-5 hr

Question 17

Fentanyl (Sublimaze)
Dose
Onset
Duration

Opioid Agonist - Mu1 & Mu2

Answer 17

Dose:
Intra op IV: 1-3 mcg/kg
Onset:
30-60 sec
Duration:
1-1.5 hrs

Question 18

Sufentanil (Sufenta)
Dose - IV & Infusion
Onset
Duration

Opioid Agonist - Mu1 & Mu2

Answer 18

Dose:
IV: 0.3-1 mcg/kg
Infusion: 0.5-1 mcg/kg/hr
Onset:
30-60 sec
Duration:
1-1.5 hrs

Question 19

Remifentanil (Ultiva)
Dose - IV & Infusion
Onset
Duration

Opioid Agonist - Mu1 & Mu2

Answer 19

Dose:
Intra op 0.5-1 mcg/kg over 1 min
Infusion: 0.125-0.375 mcg/kg/min
Onset:
30-60 sec
Duration:
6- 8 min

Question 20

Meperidine (Demerol)
Dose
Onset
Duration

Opioid Agonist - Mu1, Mu2, Kappa, Alpha2

Answer 20

Dose:
IV: 12.5 mg
Onset:
5-15 min
Duration:
2-4 hrs

Question 21

Hydromorphone (Dilaudid)
Dose
Onset
Duration

Answer 21

Dose:
Intra op IV: 1-4 mg
Post op IV: 0.5-4 mg
Onset:
5-15 min
Duration:
2-4 hrs

Question 22

Naloxone (Narcan)
Dose
Onset
Duration

Opioid Antagonist - Mu, Delta, Kappa

Answer 22

Dose:
40-80 mcg
Onset:
1-5 min
Duration:
30min

Question 23

Succinylcholine (Anectine)
Dose
Onset
Duration

Depolarizing Neuromuscular Blocking Agent

Answer 23

Dose:
1-1.5 mg/kg
Onset:
30-60 sec
Duration:
5-10 min

Question 24

Cisatricurium (Nimbex)
Dose
Onset
Duration

Non-depolarizing Neuromuscular Blocking Agent

Answer 24

Dose:
IV: 0.1mg/kg
Onset:
2-3 min
Duration:
40-75mins

Question 25

**Vecuronium (Norcuron)** Dose Onset Duration | Non-depolarizing Neuromuscular Blocking Agent

Answer 25

**Dose:** IV: 0.1mg/kg **Onset:** 2-3 min **Duration:** 45-90 min

Question 26

**Rocuronium (Zemuron)** Dose Onset Duration | Non-depolarizing Neuromuscular Blocking Agent

Answer 26

**Dose:** IV: 0.6-1.2 mg/kg **Onset:** 2-3 (1.5) min **Duration:** 35-75 min

Question 27

**Pancuronium (Pavulon)** Dose Onset Duration | Non-depolarizing Neuromuscular Blocking Agent

Answer 27

**Dose:** IV: 0.1mg/kg **Onset:** 2-3 min **Duration:** 60-120 min (1-2hrs)

Question 28

**Neostigmine (Bloxiverz)** Dose Onset Duration | Acetylcholinesterase Inhibitor

Answer 28

**Dose:** IV: 40-70 mcg/kg **Onset:** 5-10 min **Duration:** 60 min

Question 29

**Glycopyrrolate (Robinul)** Dose Onset Duration | Acetylcholine Antagonist

Answer 29

**Dose:** IV: 0.2 mg per mg/ml of neostigmine **Onset:** 1 min **Duration:** 60-120 min | 1 ml of robinul per 1 ml of neostigmine

Question 30

**Sugammadex (Bridion)** Dose Onset Duration | Aminosteroid Curare Reversal - Intermolecular/Van der Walls

Answer 30

**Dose:** IV: 2-16mg/kg **Onset:** 1-4 min **Duration:** 1.5-3 hrs

Question 31

**Sevoflurane (Ultane)** MAC Blood:Gas Vapor Pressure

Answer 31

**MAC:** 1.8 % **Blood Gas:** 0.69 **Vapor pressure:** 157 mmHg

Question 32

**Isoflurane (Forane)** MAC Blood:Gas Vapor Pressure

Answer 32

**MAC:** 1.17 % **Blood:Gas:** 1.46 **Vapor pressure:** 238 mmHg

Question 33

**Desflurane (Suprane)** MAC Blood:Gas Vapor Pressure

Answer 33

**MAC:** 6.6 % **Blood:Gas:** 0.42 **Vapor pressure:** 669 mmHg

Question 34

**Nitrous Oxide (Entonox)** MAC Blood:Gas Vapor Pressure

Answer 34

**MAC:** 104 % **Blood:Gas:** 0.46 **Vapor pressure:** Gas

Question 35

**Acetaminophen (Tylenol)** Dose Onset Duration | NSAID/COX 1&2 Antagonist

Answer 35

**Dose:** IV: 1000 mg q4-6h *Max: 3000-4000 mg* **Onset:** 30-60 min **Duration:** 6-8 hrs

Question 36

**Ketorlac (Toradol)** Dose Onset Duration | NSAID - COX 1&2 Antagonist

Answer 36

**Dose:** IV: 15-30 mg q6h *Max: 60-120 mg* **Onset:** 30 min **Duration:** 4-6 hrs

Question 37

**Ibuprofen (Caldor)** Dose Onset Duration | NSAID - COX 1&2 Antagonist

Answer 37

**Dose:** IV: 200-800 mg q6h *Max: 3200 mg qd* **Onset:** 1-2 hrs **Duration** 6 hrs

Question 38

**Dexmedetomidine (Precedex)** Dose & Mixture Onset Duration | Alpha2 Adrenergic Agonist

Answer 38

**Dose:** IV: 0.5-1 mcg/kg over 10 mins **Mixture:** 200 mcg/2 ml mixed w/ NS 48 ml = 4 mcg/ml **Onset:** 5-10 min **Duration:** 1-4 hrs

Question 39

**Lidocaine (Xylocaine)** Regional Dose Onset Duration | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 39

**Max Dose:** 5 mg/kg w/o epi 7 mg/kg w/ epi **Onset**: Rapid **Duration:** 60-120 min

Question 40

**Prilocaine (Citanest)** Regional Dose Onset Duration | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 40

**Max Dose:** 6 mg/kg w/o epi 8.5 mg/kg w/ epi **Onset:** Slow **Duration:** 60-120 min

Question 41

**Mepivacaine (Carbocaine)** Regional Dose Onset Duration | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 41

**Max Dose:** 5mg/kg w/o epi 7 mg/kg w/ epi **Onset:** Slow **Duration:** 90-180 min

Question 42

**Bupivacaine (Marcaine)** Regional Dose Onset Duration | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 42

**Max Dose:** 2.5 mg/kg w/o epi 2.5 mg/kg w/ epi **Onset:** Slow **Duration:** 240-280 min

Question 43

**Ropivacaine (Noropin)** Regional Dose Onset Duration | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 43

**Max Dose:** 3mg/kg w/o epi 4 mg/kg w/ epi **Onset:** Slow **Duration:** 240-280 min

Question 44

**Procaine (Novocaine)** Regional Dose Onset Duration | Ester Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 44

**Max Dose:** 7 mg/kg w/o epi 8.5 mg/kg w/ epi **Onset:** Slow **Duration:** 45-60 min

Question 45

**Chloroprocaine (Nesacaine)** Regional Dose Onset Duration | Ester Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 45

**Max Dose:** 6 mg/kg w/o epi 14 mg/kg w/ epi **Onset:** Rapid **Duration:** 30-45 min

Question 46

**Tetracaine (Pontocaine)** Regional Dose Onset Duration | Ester Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 46

**Max Dose:** 3mg/kg w/o epi 3 mg/kg w/ epi **Onset:** Slow **Duration:** 60-180 min

Question 47

**Bupivacaine (Marcaine)** Epidural Dose Spinal Dose | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 47

**Epidural:** 0.0625-0.125% **Spinal:** 1.25-2.5 ml

Question 48

**Ropivacaine (Naropin)** Epidural Dose Spinal Dose | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 48

**Epidural Dose:** 0.08-0.2% **Spinal Dose:** 2.5-4.5 ml | 0.08-0.2% = 0.8-2 mg

Question 49

**Lidocaine w/ Epinephrine** Epidural Dose | Amide Local Anesthetic - Voltage Gated Na Channel Blocker

Answer 49

**Epidural Dose:** 2% in 5ml bolus | 2% = 20 mg

Question 50

**Fentanyl (Sublimaze)** Epidural Dose Spinal Dose | Opioid Agonist - Mu1 & Mu2

Answer 50

**Epidural Dose:** 50-100 mcg **Spinal Dose:** 10-25 mcg

Question 51

**Sufentanil (Sufenta)** Epidural Dose Spinal Dose | Opioid Agonist - Mu1 & Mu2

Answer 51

**Epidural Dose:** 5-10 mcg **Spinal Dose:** 1.5-5 mcg

Question 52

**Morphine** Spinal Dose | Opioid Agonist - Mu1 & Mu2

Answer 52

**Spinal Dose:** 0.1-0.2 mg

Question 53

**Ephedrine** Dose Concentration Onset Duration | Indirect Sympathomimetic - Evokes NE Release

Answer 53

**Dose:** IV: 5 mg **Concentration** 50 mg/ml **Onset:** Rapid **Duration:** 60 min | Hypotension w/ bradycardia

Question 54

**Phenylephrine (Neosynephrine)** Dose Concentration Onset Duration | Direct Alpha Adrenergic Agonist

Answer 54

**Dose:** IV: 50-100 mcg **Concentration** 10 mg/ml **Onset:** Rapid **Duration:** 1 min | Hypotension w/ normal HR & tachycardia

Question 55

**Labetalol (Trandate)** Dose Concentration Onset Duration | Mixed Alpha1 & nonselective Beta1 & Beta2 Adrenergic Antagonist

Answer 55

**Dose:** IV: 5 mg **Concentration** 5 mg/ml **Onset:** 5-10 min **Duration:** 1-4 hrs | HTN & excessive SNS stimulation

Question 56

**Esmolol (Brevibloc)** Dose Concentration Onset Duration | Beta1 selective adrenergic antagonist

Answer 56

**Dose:** IV: 10 mg **Concentration** 10 mg/ml **Onset:** Rapid **Duration:** 10-30 min | HTN, tachycardia, & excessive SNS stimulation; DOC for CEA

Question 57

**Hydralazine (Apresoline)** Dose Concentration Onset Duration | Direct Vasodilator - Direct-acting smooth muscle relaxant

Answer 57

**Dose:** IV: 5 mg **Concentration** 20 mg/ml **Onset:** Slow; peaks 1 hr **Duration:** ~12 hrs | HTN

Question 58

**Sphincter of Oddi** **Spasm Treatment** Drugs of Choice & Doses

Answer 58

**Glucagon:** IV: 2 mg **Naloxone:** IV: 40 mcg **Atropine:** IV: 0.2 mg **Nalbuphine:** IV: 10 mg **NTG:** IV: 50 mcg

Question 59

**Lipid Rescue For LAST** Loading/Bolus Dose Infusion Dose | Local Anesthetic Systemic Toxicity

Answer 59

**Loading/Bolus Dose** IV: Intralipid 20% 1.5 ml/kg over 1 min *Repeat bolus up to 3 ml/kg* **Infusion Dose** IV: Intralipid 20% 0.25 ml/kg/min *Increase up to 0.5 ml/kg/min for refractory hypotension*