TH Cells/CD Markers

Question 1

TH1

Answer 1

Signal 3 Cytokines: IL-12, IL-18, IFN-gamma
TF: T-bet
Characteristic Cytokines: IL-2, IL-12, IFN-gamma, TNF-alpha
Function: Activate Macrophages

Question 2

TH17

Answer 2

Signal 3 Cytokines: IL-1 alpha/beta, IL-6, IL-21, IL-23
TF: ROR gamma T
Characteristic Cytokines: IL-6, IL-17
Function: Enhance Neutrophil Response

Question 3

TH2

Answer 3

Signal 3 Cytokines: IL-2, IL-4
TF: GATA-3
Characteristic Cytokines: IL-3, IL-4, IL-5, IL-13
Function: Activate cellular and ab response to parasites

Question 4

TFH

Answer 4

Signal 3 Cytokines: IL-6, IL-27
TF: Bcl-6
Characteristic Cytokines: IL-4, IL-21
Function: Activate B cells, maturation of ab response

Question 5

Treg

Answer 5

Signal 3 Cytokines: TGF-beta
TF: FOXP3
Characteristic Cytokines: IL-10, TGF-beta
Function: Suppress other effector T cells

Question 6

TH9

Answer 6

Signal 3 Cytokines: IL-12, TGF-beta, IFN-alpha
TF: PU.1
Characteristic Cytokines: IL-9
Function: Augment other immune responses

Question 7

TH22

Answer 7

Signal 3 Cytokines: IL-6, IL-23 IFN-alpha
TF: AHR
Characteristic Cytokines: IL-13, IL-22
Function: Keratinocyte proliferation and epidermal hyperplasia

Question 8

All Leukocytes

Answer 8

CD45+

Question 9

T cells

Answer 9

CD3+

Question 10

CD4+ and CD8+ T Cells

Answer 10

CD3+, CD4+ ; CD3+, CD8+

Question 11

B Cells

Answer 11

CD19+

Question 12

Plasma Cells

Answer 12

CD138+

Question 13

Monocytes

Answer 13

CD14+

Question 14

cDendritic Cells

Answer 14

CD68+, CD62L+

Question 15

NK Cells

Answer 15

CD16+, CD56+