Thalassemias: Chesney * Flashcards
(32 cards)
What are thalassemias?
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What is the selective advantage of thalassemias?
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Why is the alpha chain of hemaglobin very important?
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What is the normal makeup of hemoglobin in the adult?
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What is beta thalassemia?
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What is the epidemiology of beta thalassemia?
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Why does Beta thalassemia case anemia?
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What happens to bones in beta thalassemia?
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What happens to the liver and spleen in beta thalassemia?
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What are the signs and symptoms of beta-thalassemia?
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Why do patients with Thalassemia get iron overload?
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Why is there hypercoagulability in thalassemia?
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What can reduce the thrombotic complications of thalassemia?
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Why is endocrine and bone disease associated with thalassemia?
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Why is the clinical presentation of beta thalassemia so variable?
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What are target cells?
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How is beta thalassemia diagnosed?
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What is basophilic stippling?
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What diseases cause basophilic stippling?
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What are the cellular morphological characteristics of Thalassemia?
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How is Beta thalassemia diagnosed?
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How is Alpha thalassemia diagnosed?
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When is hematopoietic stem cell transplant indicated for thalassemia?
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What is hereditary persistence of Hgb F?
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