The BIG decks: B

Question 1

3. Cholinomimetics

Answer 1

carbachol pilocarpine neostigmine pyridostigmine rivastigmine edrophonium

Question 2

4. Muscarinic receptor blocking drugs

Answer 2

atropine scopolamine butyl-scopolamine ipratropium procyclidine solifenacin cyclopentolate tiotropium oxybutinine

Question 3

5. Catecholamines

Answer 3

epinephrine norepinephrine dopamine isoprenalin dobutamine

Question 4

6. Indirect sympathomimetics. Selective a2-agonists and drugs acting on the imidazoline receptors

Answer 4

ephedrine phenylephrine clonidin rilmenidine methyldopa oxymetazoline

Question 5

7. alpha-receptor antagonists

Answer 5

prazosin doxazosin tamsulozin urapidil carvedilol phentolamine

Question 6

8. beta-receptor antagonists

Answer 6

propranolol pindolol carvedilol timolol sotalol metoprolol bisoprolol nebivolol esmolol

Question 7

9. Centrally acting skeletal muscle relaxants (spasmolytics). Dantrolene. Botulinum toxin

Answer 7

baclofen tolperisone diazepam tizanidine dantrolene botulinum toxin

Question 8

10. Skeletal muscle relaxants acting on the neuromuscular junction

Answer 8

atracurium cisatracurium mivacurium pipecuronium rocuronium succynylcholine (suxamethonium)

Question 9

11. Selective B2-stimulants and other bronchodilators. Pharmacotherapy of bronchial asthma and COPD

Answer 9

salbutamol terbutaline fenoterol salmeterol formoterol ipratropium tiotropium theophyllin

Question 10

12. Antiinflammatory agents used in bronchial asthma. Antitussive agents and expectorants

Answer 10

prednisolone methylprednisolon fluticazone budesonide montelukast omalizumab codein butamirate prenoxdiazine acetylcystein bromhexin

Question 11

13. Drugs used for the treatment of peripheral vascular diseases. Therapy of migraine

Answer 11

vinpocetin nicergolin cilostazol pentoxifyllin Ca-dobesilate sumatriptan galkanezumab cinnarizin propranolol verapamil carbamazepine valproate imipramine

Question 12

14. Drugs used for treatment of heart failure I: Drugs decreasing the load on the heart. Drugs of acute cardiac failure. Pharmacotherapy of chronic heart failure.

Answer 12

see ACE-inhibitors, diuretics, beta-blockers, etc.

Question 13

15. Drugs used for treatment of heart failure II: Positive inotropic agents. Pharmacotherapy of acute heart
    failure.

Answer 13

digoxin digitoxin milrinone levosimendan dobutamine

Question 14

16. Antiarrhytmic agents

Answer 14

lidocaine propafenone esmolol amiodarone sotalol verapamil adenozine digoxin Mg++

Question 15

17. Drugs used for the treatment of hypertension I: Classification of antihypertensive agents and their
    mechanisms of action. Pharmacotherapy of hypertension

Answer 15

B18-B19 and sympatholytics, diuretics

Question 16

18. Drugs used for the treatment of hypertension II: Ca++-channel blockers and other vasodilators

Answer 16

amlodipine felodipine nifedipine nimodipine verapamil dihydralazine bozentan sildenafil

Question 17

19. Drugs used for the treatment of hypertension III: Drugs acting on the renin-angiotensin-aldosterone
    system

Answer 17

enalapril perindopril ramipril losartan valsartan valsartan + sacubitril irbesartan spironolactone eplerenon captopril

Question 18

20. Drugs used for treatment of angina pectoris. Pharmacotherapy of ischemic heart disease.

Answer 18

nitroglicerin isosorbid-mononitrate trimetazidine ivabradin beta-bockers and Ca-channel blockers

Question 19

21. Agents used in dyslipidaemias

Answer 19

simvastatin atorvastatin rosuvastatin ezetimib fenofibrate colesevelam

Question 20

22. Potassium excreting (wasting) diuretics

Answer 20

acetazolamide hydrochlorothiazide indapamide furosemide etacrynic acid

Question 21

23. Potassium sparing diuretics, ADH antagonists, osmotic diuretics

Answer 21

spironolactone eplerenone amiloride tolvaptan mannitol glycerol

Question 22

24. Histamine and antihistamines

Answer 22

promethazine diphenhydramine (levo)cetirizine (des)loratadine dimetinden fexofenadin

Question 23

25. Natural opiates, opioid receptors

Answer 23

morphine codeine

Question 24

26. Semisynthetic and synthetic opiates

Answer 24

hydromorphone dihydrocodeine oxycodone buprenorphine nalbuphine meperidine =(pethidine) fentanyl methadone tramadol diphenoxylate loperamide naloxone methyl-naltrexone

Question 25

27. General properties of NSAIDs. Acetylsalicylic acid

Answer 25

acetylsalicylic acid colchicin allopurinol rasburicase

Question 26

28. NSAIDs, except acetylsalicylic acid. Non-opioid and adjuvant analgesics. Drugs used for treatment of gout. Treatment strategy of pain

Answer 26

metamizole naproxen ibuprofen (dex)ketoprofen phenylbutazone indomethacin diclofenac meloxicam celecoxib paracetamol

Question 27

29. Immunopharmacology I. (cytotoxic agents, retinoids). Pharmacotherapy of autoimmune diseases.

Answer 27

cyclophosphamide methotrexate leflunomide azathioprin mycophenolate-mofetil

Question 28

30. Immunopharmacology II. (Inhibitors of cytokine gene expression, 5-ASA derivatives)

Answer 28

cyclosporin A tacrolimus sirolimus tofacitinib sulfasalazine

Question 29

31. Immunopharmacology III. (Antibodies and fusion proteins)

Answer 29

ATG (antithymocyte-globulin) rituximab infliximab adalimumab tocilizumab ustekinumab natalizumab dupilumab abatacept

Question 30

32. Cancer chemotherapy I (antimetabolites)

Answer 30

5-fluorouracyl capecitabine cytarabine 6-merkaptopurine methotrexate pemetrexed

Question 31

33. Cancer chemotherapy II (alkylating agents)

Answer 31

cyclophosphamide dacarbazine temozolomide cisplatine oxaliplatin dactinomycin bleomycin

Question 32

34. Cancer chemotherapy III (Topisomerase inhibitors. Inhibitors of mitotic spindle)

Answer 32

irinotecan etoposide doxorubicin vincristine docetaxel

Question 33

35. Cancer chemotherapy IV. (Hormonal agents)

Answer 33

tamoxifen anastrozole goserelin degarelix bicalutamide prednisolone octreotide

Question 34

36. Cancer chemotherapy V. (Small molecule signal transduction inhibitors)

Answer 34

imatinib gefitinib erlotinib lapatinib sunitinib ibrutinib crizotinib bortezomib dabrafenib+ trametinib everolimus tretinoin

Question 35

37. Cancer chemotherapy VI. (Large molecule signal transduction inhibitors.)

Answer 35

trastuzumab (-emtansin) panitumumab rituximab bevacizumab alfa-interferon aldesleukin pembrolizumab