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Pharmacy Calculations And Body System Theory > The Body And Drugs > Flashcards

The Body And Drugs Flashcards

1
Q

Pharmacodynamics

A

Study of how drugs produce their effects on desired cells and how a drug is processed by the body

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2
Q

Drug receptors can be compared to a

A

Lock

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3
Q

Location where a drug will exert its desired effect

A

Site of action

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4
Q

Mechanism of action (MOA)

A

Explains how a drug works and produces its desired effect on the body

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5
Q

Receptor site

A

Where the drug binds to the cell

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6
Q

Agonist

A

Specific type of dug that produces a certain and predicted action

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7
Q

Antagonist

A

Drug that does not produce any noticeable or desirable effects of its own, but blocks other chemicals from attaching to a receptor cell

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8
Q

Desired effect

A

Body’s response to a drug /intended response to a med

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9
Q

Dose response curve

A

Indicates the body’s response to a drug is directly related to the amount of the drug taken

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10
Q

Ceiling

A

Maximal response the body as to a drug

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11
Q

ED50

A

The measurement of the specific amount that is needed to achieve 50% of the maximal response

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12
Q

Half-life

A

Time required for plasma serum concentration levels of an absorbed and distributed drug to decrease by one half

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13
Q

Half life is written as

A

T1/2

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14
Q

Time response curve

A

Length of time in which a specific drug will continue to have same degree of effects

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15
Q

Pharmacokinetics

A

Study of time course of a drug and its metabolites in the body following drug administration by any route

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16
Q

Pharmacokinetics

A

Study of drug movement throughout the body

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17
Q

Absorption

A

Process by which the drug is moved from its site of administration into the blood steam

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18
Q

Intravenous

A

Type of drug administration that bypasses some of the aspects of absorption

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19
Q

Distribution

A

Process that the drug is moved from the blood stream to the body tissue or receptors

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20
Q

Passive diffusion

A

Movement of a substance across a cell membrane

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21
Q

Facilitated diffusion

A

A carrier protein permits specific molecules to pass though certain parts of the cell

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22
Q

Pinocytosis

A

The cell engulfs the substance and permits the substance to enter the cell

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23
Q

More lipid soluble drug is the more. , the drug will be absorbed into a cell

A

Quickly

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24
Q

Clearance

A

Time it takes a drug to be eliminated from the body

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25
Q

Addiction

A

Pattern of compulsive substance abuse characterized by a continued psychological and physiological crabbing or need for the substance and its effects

26
Q

Characteristics of addiction

A

Absorbed focus, painful withdrawal, damaging consequences

27
Q

Number of Americans addicted to alcohol

A

14 million

28
Q

Number of deaths associated with alcohol per year

A

100,000

29
Q

Excessive alcohol drinking while taking warfarin can cause

A

Blood clots

30
Q

Occasional alcohol drinking while taking warfarin can cause

A

Internal bleeding

31
Q

Treatments for alcoholism

A

Disulfiram, acamprosate calcium, naltrexone

32
Q

Drug treatments for smoking cessation

A

Bupropion, verenicline, nicotine polaerilex

33
Q

Bioavailability

A

Degree to which a drug becomes available to tissues after administration

34
Q

Metabolites

A

Any substance produced by the metabolic process

35
Q

Excretion

A

Process by which drugs are eliminated from the body

36
Q

A drug that is designed to produce an action rather than stop an action

A

Agonist

37
Q

Drug works by blocking he action of a receptor

A

Antagonist

38
Q

Potency is the measure meant of the ___ of the drug that is required to have a specific effect on the body

A

Strength

39
Q

Chemicals that do not readily cross the cell membrane barrier

A

Ionized

40
Q

Metabolism

A

Bio transformation

41
Q

A drug that binds directly to cell membranes and is not absorbed by the body in any way

A

Metamucil

42
Q

Facilitated diffusion

A

Type of drug transportation into the cell that does not require the cell to expand energy

43
Q

When a chemical bind with a ______, it is stimulated to either produce or inhibit a specific action

A

Receptor

44
Q

First pass process

A

Process which the liver begins the absorption of an oral medication

45
Q

Maximal drug response to a drug reaches the ceiling, it can be toxic especially to

A

Liver and kidneys

46
Q

Absorption

A

Process of movement of the drug from the circulatory system across airier membranes to the site of a drug action

47
Q

Elimination

A

Process that results in removal of drug from the body and the discontinuation of the drug action

48
Q

Metabolism

A

Biochemical process involving transformation of active drugs to a compound that can be easily eliminated or inactive drugs to active drugs

49
Q

1 ml = gtt

A

120

50
Q

5tbsp =. ml

A

25ml

51
Q

120mg =. gr

A

0.120 gr

52
Q

0.5 gr =. mg

A

500mg

53
Q

10g =. mcg

A

10,000,000

54
Q

8oz =. ml

A

236ml

55
Q

44kg =. Lbs

A

96.8lbs

56
Q

1pt =. Cc

A

473.17cc

57
Q

2c =. Oz

A

16oz

58
Q

1.5l =. Cc

A

1,500 cc

59
Q

15tsp =. Oz

A

2.5oz

60
Q

Target cell

A

Large number of cells all of which are similar to each other

61
Q

Albumins and globulins

A

Proteins that help with transporting chemicals though the blood

62
Q

Alcohol is a

A

Depressant

Pharmacy Calculations And Body System Theory (8 decks)

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