The Brain Flashcards

(43 cards)

1
Q

What is the brain and how much does it weigh?

A
  • Co-ordinating centre of sensation and intellectual activity.
    -Adult brain weighs 1.5kg and contains 8.6 x 10^6 neurones, each making more than 1000 connections.
  • In addition there are about 10^12 gilal cells supporting the functions of the neurones.
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2
Q

What is the meninges?

A
  • Brain is continuous with spinal cord and both are surrounded by three membranes, or meninges.
    -The delicate pia mater is on the brain surface.
    -The thick dura matter is attached to the skull.
    -The arachnoid mater is between.
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3
Q

What is meningitis?

A
  • An inflammation of the meninges.
  • Viral meningitis is more common than bacterial meningitis which can be fatal.
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4
Q

What are the ventricles of the brain?

A
  • Four connected cavities in the brain into which cerebro-spinal fluid is secreted.
  • Cells lining the ventricles produce cerebro-spinal fluid, which circulates between the ventricles and is passed into the spinal canal.
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5
Q

Why does cerebro-spinal fluid resemble plasma in its components?

A
  • Supplies nutrients eg glucose.
  • Supplies oxygen, carried in solution. Cerebro-spinal fluid does not contain red blood cells and is pale yellow in colour.
  • Contains antibodies and white blood cells, giving it a role in resisting infection.
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6
Q

What are the three regions of the brain?

A
  • The forebrain
  • The midbrain
  • The hindbrain
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7
Q

What is the hindbrain?

A
  • The most primitive part of the human brain. It sustains basic homeostatic functions. Contains the cerebellum and medulla oblongata.
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8
Q

What is the cerebellum?

A
  • Has a convoluted surface, providing space for the cell bodies of a large number of neurones.
  • Co-ordinates voluntary tasks requiring fine muscle control, eg writing and playing scales rapidly, and controls the muscles to maintain posture.
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9
Q

What is the medulla oblongata?

A

Connects to the spinal cord, controls basic functions including ventilation, maintaining blood pressure and balance and regulation of heart beat.

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10
Q

What is the midbrain?

A

Contains nerve fibres linking the hindbrain and the forebrain, that relay information for vision and hearing.

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11
Q

What is the forebrain?

A

Contains the limbic system and the cerebrum.

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12
Q

What is the limbic system and what does it contain?

A
  • Associated with emotion, learning and memory.
  • Contains the hippocampus, thalamus and hypothalamus.
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13
Q

What is the hippocampus?

A

Interacts with the cerebral cortex, contributing to learning, reasoning, personality and consolidating memory into a permanent store.

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14
Q

What is the thalamus?

A

A relay centre, sending and receiving impulses to and from the cerebrum.

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15
Q

What is the hypothalamus?

A
  • Controls general functions eg body temperature, blood solute concentration, hunger, thirst and sleep.
  • Main controlling region of the autonomic nervous system and links the brain to the endocrine system through the pituitary gland.
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16
Q

What is the cerebrum?

A

Two hemispheres responsible for integrating sensory functions and initiating voluntary motor functions eg learning, reasoning, personality and memory. Most of it’s functioning is subconscious. It is more developed than other animals.

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17
Q

What is the autonomic nervous system?

A

It is a part of the peripheral nervous system and controls the continuous functioning of internal organs without conscious intervention by the antagonistic activity of the sympathetic and parasympathetic nervous systems.
The processes it controls are sometimes described as being automatic and include reflex actions such as swallowing, coughing, vomiting and sneezing.

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18
Q

What is the autonomic nervous system regulated by?

A

It is regulated by the hypothalamus and there are two antagonistic components.

19
Q

What is the sympathetic nervous system?

A

It uses the neurotransmitter noradrenalin. This acts in a similar fashion to adrenalin, and so the sympathetic nervous system is excitatory. Its nervous impulses increases heart rate, blood pressure and ventilation rate. The cell bodies of the sympathetic neurones are in the grey matter of the spinal cord and the ganglions lying outside of the spinal cord.

20
Q

What is the parasympathetic nervous system?

A

It uses the neurotransmitter acetylcholine. It generally has an inhibitory effect, decreasing the heart rate, blood pressure and ventilation rate. The cell bodies of the parasympathetic neurones are in the brain and spinal cord and others lie close to the target organs.

21
Q

What happens when blood pressure increases?

A

An increase in blood pH or blood pressure increases the heart rate. These responses are under automatic control by the cardiovascular centre in the medulla oblongata.

22
Q

What happens to the heart rate during exercise?

A
  • The cardio-acceleratory centre is stimulated.
  • Nervous impulses travel along the sympathetic nerve fibres to the sino-atrial node (SAN).
  • The neurotransmitter noradrenalin is released.
  • Noradrenalin binds to the cell membrane receptros on SAN cells.
  • The SAN’s electrical discharge increases in frequency.
  • The heart rate increases.
23
Q

What happens to the heart rate during sleep?

A
  • The cardio-inhibitory centre is stimulated.
  • Nervous impulses travel along the parasympathetic nerve fibres to the SAN.
  • The neurotransmitter acetylcholine is released.
  • Acetylcholine binds to cell membrane receptors on SAN cells.
  • The SAN’s electrical discharge decreases in frequency.
  • The heart rate decreases.
24
Q

What are the two cerebrum hemispheres connected by?

A

They are connected by fibres which run through the corpus callosum which is the largest white matter structure in the brain.
The structure of the corpus callosum may explain why some parts of the brain are lateralised, which means that they appear to function somewhat differently in the two hemispheres.

25
What is the outer 2-3mm of the cerebrum?
The cerebral cortex, it's neurones have their axons deeper in the brain than their cell bodies. The axons are myelinated but cell bodies are not so, unlike the spinal cord, in the cerebrum grey matter surrounds white matter.
26
How does the cerebral cortex differ in mammals and reptiles and fish?
Reptiles and fish have a small and simple cerebral cortex, mammals have a larger and more complex cerebral cortex, also known as the neocortex. Like the cerebellum, it's surface is highly folded, producing a larger surface area, fitting in a larger number of neurones than if the surface were sooth.
27
What is the neocortex?
Has the order of 2x10^10 neurones. Their high connectivity is thought to be responsible for the cerebrum executing higher cognitive functions including language, conscious actions, thought and processing sensory input. The cerebrum is strongly integrated with the thalamus, in he limbic system.
28
What are the four lobes of the cerebral hemispheres?
Frontal, temporal, parietal and occipital.
29
What are the properties of the frontal lobe?
- Aspects of personality. - Site of reasoning, planning, emotions and problem solving. - The dominant hemisphere includes Broca's area, which controls the motor aspects of speech. - Contains motor cortex.
30
What are the properties temporal lobe?
- Includes the auditory cortex so generates the sense of sound. - Processes complex stimuli, eg face, scenes. - Has roles in learning and memory. - The left temporal lobe contains Wernicke's area, which is associated with written and spoken speech. - Temporal lobes are not lateralised so unlike other areas of the brain neither is dominant.
31
What are the properties of the parietal lobe?
- Associated with sense of taste. - Has a role in visuo-spatial processing. - Includes the somatosensory cortex.
32
What are the properties of the occipital lobe?
- Contains the primary visual cortex and is associated with vision.
33
What are the three areas of the cerebral hemisphere?
Sensory areas, motor areas and association areas.
34
What is the role of the sensory areas? (somatosensory cortex).
Recieve nervous impulses from the sense receptors of the body, via the thalamus. Nerve fibres from the two sides of the body cross over in the corpus callosum, so the sensory area in the cortex of one hemisphere processes information from the sense receptors of the other side of the body.
35
What are the roles of the motor area (motor cortex)?
Send nervous impulses through the corpus callosum, to the effectors on the other side of the body.
36
What are the roles of association areas?
- Recieve nervous impulses from sensory areas. - Associate new information with stored information, generating meaning. - Interpret, process and store visual information in the visual association area. - Interpret, process and store auditory information in the auditory association area.
37
What is a stroke?
A stoke is an interruption to blood flow in the brain. A cerebral artery fails to deliver oxygen to the neurones of the brain and so they die. This is an infarction.
38
What are the two types of stroke?
Ischaemic and haemorrhagic.
39
What are ischaemic strokes?
87% of stokes are ischaemic strokes. This is when blood vessels become blocked and it can be caused by a blood clot or thrombus, forming at the site, and an embolus which is material travelling in the blood stream. If it is detected within about 4 hours it may be treated successfully with "clot-busting" medication.
40
What are haemorrhagic strokes?
Caused by bleeding into the brain or the space around it, which can produce an intense headache. This makes up around 13% of strokes.
41
What happens when brain cells die as a result of a stroke?
- Nervous impulses can no longer travel along their fibres from the brains motor areas to effectors, causing paralysis which may only be on one side of the body. Muscle tone is lost because no muscle fibres are stimulated and so the face may droop.
42
What happens at the corpus callosum?
Nerve fibres cross over and so a stroke on one hemisphere of the cerebrum affects the body on the opposite side.
43
What are the risk factors for strokes?
The main risk factors for stroke include a high blood pressure but tobacco smoking, obesity and high blood cholesterol increase the risk. Risk increases with age, and are diagnosed with CT and MRI scans and a ECG and blood test can rule out other possible causes.