The Brain and Behavior - Biological Approach Flashcards
(52 cards)
Methods in Biological Approach
Case Studies
Case Studies
Often provide researchers w/ a situation they could never ethically reproduce in a lab
→ often longitudinal to observe both short-term and long-term effects of damage
Longitudinal Studies
Correlational research that involves repeated observations of the same variables over long periods of time
→ holistic: range of effects of the damage (rather than one behavior)
Use triangulation: may include interviews w/ family, psychometric testing (IQ/Personality testing), experiments and observations
Triangulation: involves using multiple data sources, multiple researchers or multiple research methods to reach a richer understanding of a behavior/cognitive process
limitations in biological approach
Researchers do not manipulate an IV
No cause & effect relationship can be established
Case studies are individual: cannot be generalized to all humans
Cannot be replicated as it naturally occurring
May be difficult to verify info about P. before incident
Info on patients IQ, problem solving skills, memory or interpersonal skills is often reliant on memory of family
Not accurate measure & memory may not be accurate
strengths in biological approach
Provide important info to study effects of brain damage over time & spark new research
Psychologists often use similar research to verify findings
May perform research on animals to investigate hypothesized relationship between damage to a specific area of the brain & behavior
Techniques in Biological Approach, and why use technology?
MRI, fMRI, PET
because allows reseacher to see localization of function - functions of parts of brain & how they react to behavior
MRI
→ HM: Milner 1966; Maguire 1999; Eugene Pauly
Magnetic resonance imaging
Gives 3D picture of brain structure
Used with HM to determine extent of damage
Uses magnetic field & radio waves to map activity of hydrogen molecules present in different brain tissue to different degrees
Can be viewed as slice from any angle or 3D view of the brain
advantages of MRI
Non-invasive process: minimal potential of harm
High resolution: gives R. good idea of brain structure
limitations of MRI
Only indicates structure
Does not map what is actually happening
Correlational in nature: no clear cause & effect can be established
fMRI
functional MRI
→ Baumgartner et al. 2008; Harris & Fiske 2006; Sharot et al. 2006
Shows brain activity & indicates which areas of brain are active when engages in behavior/cognitive processes
Measures changes in blood flaw in active brain
Oxygen level as measurement of neural activity
Active brain uses more oxygen & blood flow increases
advantages of fMRI
Higher resolution than PET scans
Easier to carry out
non-invasive : no radio-isotope necessary
Produces a film that demonstrates change in brain activity
limitations of fMRI
Non-natural environment for cognition
Lack of ecological validity
P. may experience anxiety due to claustrophobic nature of machine
Artifacts in imaging: brain activity may be related to anxiety/reaction to machine
Artifacts: Something observed in a scientific investigation/experience that is not naturally present but occurs as a result of an investigative process
Use of color may be exaggerated
Much of activity in brain is spontaneous & not a reaction to stimuli
Difficult to know exactly which areas of the brain are active in a behavior
For both MRI and fMRI iron objects must be removed
Sample size may be reduced due to metal implants
PET
Positive emission tomography
Observe metabolic processes in brain by detecting gamma rays emitted by a tracer
Based on the assumption that areas of high radioactivity are associated w/ brain activity
P. given safe dose of radioactive tracer compound
Through modified glucose molecules (FDG)
Injected into blood & can enter brain
More glucose needed in active areas, and thus PET detects radioactive tracer
30min-2hrs
Produced multi-colored image of where brain is most active
advantages of PET
Allows participants to perform psychological tasks while brain activity is observed
limitations of PET
Injection w/ small amount of radioactive material
Not cause harm but is an invasive practice & raises ethical concerns
Slow & poor resolution
localization and plasticity
Localization of function describes the theory that specific parts of the brain are responsible for specific behaviors/cognitive processes. HM case study is evidence of this theory - the hippocampus being responsible for transferring short-term memory to long-term.
E.g. memory research. Cognitive processing is argued to be the result of distributive processing rather than localization of function - parts of the brain have to work together to create and retrieve memories.
4 key areas of brain
BRAIN STEM: regulating life functions (e.g. breathing, heart rate, and blood pressure)
CEREBELLUM: balance and motor functions including speech production. Additionally in learning (classically conditioned responses)
CEREBRUM: initiates and coordinates movement and regulates temperature
LIMBIC SYSTEM: behavioral and emotional responses
4 sections of cerebral cortex
THE FRONTAL LOBE: executive functions (planning, decision-making, and speech)
THE OCCIPITAL LOBE: visual processing
THE PARIETAL LOBE: perception of stimuli
THE TEMPORAL LOBE: auditory processing and memory
Study of HM what type of method?
Case Study
Study of HM context
WILLIAM SCOVILLE performed experimental surgery: removed tissue from medial temporal lobe (inc. hippocampus) on both side of HM’s brain
After op. HM remembered childhood well & personality was unchanged
HM suffered from anterograde amnesia
No longer able to transfer info from STM to LTM
HM Study (info)
localization
AIM: To study the role of the hippocampus on memory formation in a longitudinal case study
PROCEDURE:
Example of method triangulation
Psychometric testing: 12 tests were given, and results were above average
Direct observation of behavior
Interviews w/ HM & family members
Cognitive testing: memory recall & learning tasks (s.a. reverse mirror drawing)
MRI to determine extent of damage done (CORKIN 1997)
FINDINGS:
HM could not acquire new episodic knowledge (memory of events) or new semantic knowledge (general knowledge about the world)
Suggests brain structures removed important for LTM (explicit memory)
Was able to form a cognitive map of the spatial layout of his home
Had capacity for working memory, as he could hold a normal conversation
Procedural memories well maintained
Showed improvements on performance of new skills (s.a. Rev. mirror drawing)
According to MRI scans from 1997 & 2002 (CORKIN) the temporal lobe (inc. hippocampus) had most damage: explains problem of transferral of STM to LTM
→ Researchers conclude Hippocampus plays critical role in converting memory from STM to LTM
Not site of storage of STM or LTM, but plays role in organization & storage of permanent memory elsewhere in brain
Brain Plasticity
brain’s ability to alter its own structure between neurons following the changes within the body or in the external environment. High levels of stumulan and learning opportunities lead to an increase in the density of neural connections
what type of method was used in MAGUIRE ET AL. (2000)
quasi (case and effect)
Maguire et al. (2000)
brain plasticity
AIM: See whether the brains of london taxi drivers would be somehow different as a result of exceptional training they have to do to be certified
PROCEDURE:
16 right-handed male london taxi drivers
brains were MRI scanned & compared w/ MRI scans of 50 right-handed males who don’t drive taxis (control)
In order to take part in study, P. had to complete ‘the knowledge’ & have licenses for at least 1.5 years
Controls taken from MRI database
Included range of ages so that age wasn’t confounding variable
Study is correlational
IV is not manipulated, but is naturally occuring
R. looking to see if there was a relationship between no. of years driving a taxi & anatomy of one’s brain
double-blind study - researcher did not know whether they were looking at a taxi scan or control
FINDINGS:
Posterior hippocampi of taxi drivers were significantly larger than control
Anterior hippocampus significantly smaller
Volume of right posterior hippocampus correlated w/ amount of the time spent as a taxi driver
No other differences observed in other parts of the brain
Maguire argues that this demonstrates that the hippocampus may change in response to environment and demands