The Cell Cycle and Cell Division Flashcards
What is the longest part of the cell cycle ?
Interphase
What acronym can be used to describe processes in interphase ?
ROPA
R = Replication of DNA
O = Organelles Produced
P = Protein Synthesis
A = ATP Synthesis
What is the order of mitosis ?
Interphase
Prophase
Metaphase
Anaphase
Telophase
Cytokinesis
Prophase (Mitosis)
- Chromosomes condense and become visible.
- Centrioles move to opposite poles in an animal cell
- Spindle Fibres form
- Nuclear membrane disintegrates and nucleolus disappears
Metaphase ( Mitosis)
- centromeres of chromosomes attach to spindle fibres and line up at the equator
Anaphase (Mitosis )
- Centromeres seperate
- Spindle fibres contract and pull to opposite poles, seperated chromatids are now called chromosomes
Telophase (Mitosis )
- Chromosomes uncoil and lengthen
- Spindle fibres break down
- Nucleolus and nucleur membrane reappear
Centrioles in animal and plant cells
Animal = Present
Plant = Absent
Cytokinesis (Mitosis)
- Divides the cytoplasm to produce 2 genetically identical diploid daughter cells
The significance of Mitosis
-Growth, repair tissue and replaced dead cells
Damage of genes ( Mitosis )
- damages genes occur due to radition, certain chemicals or viruses that mutate DNA.
- If the gene is broken the cell may undergo repeated rounds of mitosis if this happens to solid tissue then a tumour may form
Working out the mitotic index
N of cell in pro+meta+ ana+telo
/
Total number of cells
x 100
Where does meiosis take place
Reproductive organs
Prophase 1 (Meiosis)
- Paternal and maternal chromosomes come together and form homologous pairs
- The pairing is called synapsis
- Each pair is bivalent
- Chromosomes condense and coil
- Cromatids wrap around eachother and partially repel but remain joined at the chlasmata.
- A segment of DNA is exchanged = crossing over and is a source of genetic variation
- At the end th nucleur envelope and nucleolus disappears
Metaphase 1 (meiosis)
- Pairs of homologous chromosomes arrange themselves at the equator
- One chromosome is mother and the other father, these lie randomly at the equator = independent assortment