Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

NAPLEX D: > The crap never ends > Flashcards

The crap never ends Flashcards

(327 cards)

Start Studying
1
Q

What is prinzmetal’s angina

A

Vasospasm that occurs at rest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Regadenoson used for

A

pharmacologic stress test

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Lexiscan

A

Regadenoson

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Treatment of ischemic heart disease - antiplatelet

A

aspirin (or clopidogrel if allergic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Treatment of ISHD - anti-anginal

A

Beta–blockers (first line)
CCBs
Ronalazine (can be with beta-blockers)
Nitrates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

HR goal for beta-blockers in ISHD

A

55-60bpm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

First-line treatment for prinzmetal’s angina

A

CCBs (NOT nifedipine IR)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ronalazine ADEs

A

QT prolongation
CYP3A4 inhibitor
Does NOT lower HR/BP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Nitrates vasodilate veins or arteries more?

A

Veins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Nitrostat

A

SL tablet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

NitroMist

A

nasal spray

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

GoNitro

A

SL powder

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How long nitrate free period to prevent tachyphylaxis?

A

10-12 hours

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

How is nitroglycerin ointment measured?

A

With the dose measuring applicator it comes with

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Where should nitrate patch be applied?

A

to chest

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Monoket

A

Isosorbide mononitrate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What treatment modalities for ISHD?

A 
A - antiplt/anticoag
B - blood pressure/beta blocker
C - cholesterol, cigs
D - diet and DM
E - exercise and education
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What can be a HD?

A

Teratogen
Reduced fertility
organ toxicity at lower doses

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the list of HD found?

A

NIOSH

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Some drugs you might not have known were hazardous - 8

A 
Ribavirin
Colchicine
Fluconazole
Spironolactone
Risperidone
Rasagiline
Ziprasidone
Dronedarone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

How far apart to separate sterile and non-sterile C-PECs?

A

1 meter

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Required ACPH for C-SEC and buffer room?

A

C-SEC: 12

Buffer room: 30

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Class I or Class II BSC is non-steirl HD?

A

Class I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

When are closed system transfer devices REQUIRED?

A

administering antineoplastics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
What are requirements for receiving HDs?
single loves and N-95 mask
26
What types of HD require full face respirator or faceshield and goggles?
gas/vapors/splashes
27
Where to store antineoplastics?
negative pressure room
28
PPE for administering HD?
2 gloves for antineoplastics | gown for antineoplastics
29
How to crush HD?
In a plastic pouch
30
How to dispose of HD?
Yellow bin - trace; outer gowns, shoe cover | Black bin - bulk
31
Sanitization order of HD
1. Deactivation and decontamination (remove HDs - bleach/peroxide) 2. Clean (Germicidal detergent) 3. Disinfect (IPA)
32
How often to check for HD residue (environmental monitoring)
6 months
33
Heparin/LMWH antidote
protamine
34
Beta-blocker antidote
glucagon
35
CCB antidote
Calcium
36
Drugs that can worsen PD
Metoclopramide Antipsychotics Antiemetics
37
Major symptoms of parkinson's
Tremor Rigidity Akinesia Posture
38
Treatment options for PD
1. Carbidopa/levodopa 2. Dopamine agonists 3. Amantadine/MAO-B inhibitors
39
Carbidopa dose
75-100mg/day
40
Rytary
carbidopa/levodopa capsule (can be sprinkled)
41
Sinemet
Carbidopa/levodopa
42
Mirapex
Pramipexole
43
Requip
ropinirazole
44
Neupro
Rotigotine patch
45
ADEs of Sinemet
nausea, dark urine, priapism, positive Coombs test, dyskinesia
46
CI of Sinemet
MAO-Is
47
what is entacopone
COMT inhibitor - increases duration of levodopa | 200 mg with each dose of levodopa
48
ADEs of dopamine agonist
somonlence orthostasis hallucination
49
What are the dopamine agonists?
ropinirole pramipexole riotigotine
50
What is apomorphine and what ADE?
Rescue injection for parkinson's | Causes severe N/V
51
How to treat N/v with apomorphine
Trimethobenzamide (Serotonin antagonists contraindicated)
52
Amantadine MOA
blocks DA reuptake
53
Amantadine ADEs
decreased BP, somnolence, psychosis
54
MAO-B inhibitors
selegiline, rasagiline, safinamide
55
MAOB inhibitors CI (3 drug classes)
with MAOIs, opioids, SNRIs
56
ADEs of MAO-B inhibitors
HTN, activating (selegiline), serotonin syndrome
57
Droxidopa use
orthostatic hypotension
58
What can cause osteoporosis (5)
``` Heparin Steroids Lithium SSRIs excess thyroid ```
59
Normal t-score
>= -1
60
Rickets
Vitamin D deficiency
61
Calcium daily dose
500-600mg
62
Ca citrate or Ca carbonate has better absorption with PPIs?
Calcium citrate
63
Vitamin D deficiency level
<30
64
Which bisphosphonates are monthly>
PO ibandronate, risedronate
65
Atelvia CI
DR risedronate - with PPIs and H2RAs
66
Reclast
zoledronic acid
67
Evista
raloxifene
68
Duavee
estrogen/bazedoxifene
69
Forteo
teriparatide
70
Evista is used for treatment or prevention?
Both (raloxifene)
71
ADEs of raloxifene
arthralgias leg cramps VTE/stroke
72
Max use of teriparatide and why
2 years - osteosarcoma risk
73
ADEs of teriparatide
arthralgias, increased Ca, cramps, pain, nausea, dizziness
74
Does teriparatide need fridge?
yep
75
Denosumab MOA
decreases osteoclasts
76
Denosumab ADEs
``` ONJ, AFF, increased BP N/V/D edema SOB low phosphate ```
77
Calcitonin ADE
inhibits osteoclasts
78
Calcitonin ades
hypercalcemia, increased malignancy risk | Do not use if HSR to salmon
79
estrogen increases risk of what without progestin?
endometrial cancer
80
estrogen ades
breast cancer clots dementia
81
Which estrogen patches are applied twice weekly?
Vivelle-Dot | Alora
82
Which estrogen patches are applied weekly?
Climara
83
Provera
medroxyprogesterone
84
Natural prodcuts for menopause
``` Black cohosh Dong quai red clover soy flaxseed primrose oil SJW ```
85
SSRIs for vasomotor symptoms?
paroxetine (Brisdelle)
86
CI medication for paroxetine?
NOT with tamoxifene
87
Meds for vasomotor symptoms
``` SSRIs SNRIs clonidine gabapentin pregabaline ```
88
Ospemifine use
painful intercourse (SERM)
89
What drugs cause hypogonadism in males
Methadone Cimetidine Spironolactone Chemo
90
Who should get testosterone treatment?
men who are symptomatic and have confirmed low testosterone
91
Risk with testosterone treatmetn?
CV Clotting Increased HcT increased prostate (avoid with BPH)
92
ADEs of testosterone
hepatotoxicity, decreased sperm, edema
93
Where to apply AndroGel
Upper body
94
When to apply AndroDerm
(patch) | nightly
95
Striant
testosterone buccal tablet
96
Depo-Testosterone
testosterone cypionate - IM injection
97
Risk if kids get into testosterone?
Virilization
98
Neurotransmitters that affect depression
``` serotonin NE DA EPI glutamine Acetylcholine ```
99
What's the depression scale?
HAM-D, HDS
100
How long to treat with antidepressant before counting as failure?
6-8 weeks
101
Risk of SSRIs and pregnancy?
Pulmonary hypertension
102
Preferred drug in post-partum?
SSRIs | TCAs
103
Which improves first - physical or mood symptoms of depression?
Physical
104
Max dose of citalopram - and why?
40mg (20mg in elderly) | QT prolongation
105
ADEs of SSRIs
``` Dry mouth Sweating Weakness Tremor HA Bleeding Sexual dysfunction SIADH ```
106
Vilazodone MOA
SSRI and 5HT1A partial agonist
107
SNRI ADEs
dilatd pupiles constipation dry mouth sweating
108
Max dose of venlafaxine and why
375mg | QT prolongation
109
TCA ADEs
QT prolongation (overdose) orthostasis anticholinergics
110
Tertiary TCAs
doxepin amitriptyline (more effect but more ADEs)
111
Secondary TCA
nortriptyline
112
MAO-Is
Isocarboxazide Phenelizine Tranylcypromine
113
contraindication with MOAIs
Tyramine foods | Drugs that increase DA, NE, EPI, 5-HT
114
How long to wash out other antidepressants before starting MAOIs?
2 weeks | 5 for fluoxetine
115
Bupropion MOA
DA and NE reuptake inhibitor
116
Buprpion ADEs
dry mouth insomnia tremors decreased weight
117
Benefit of bupropion
No sexual dysfunction
118
Mirtazapine ADEs
sedation | increased appetite/weight gain
119
Trazodone ADEs
sedation | priapism
120
Nefazodone ADEs
hepatotoxicity
121
What atypical antipsychotics for depression?
quetiapine brexipiprazole olanzapine/fluoxetine
122
What medications for induction of immunosuppression?
Basiliximab (simulect) | Antithymocyte globulines
123
ATGAM and thymoglobulin - which is horse and which is rabbit
ATGAM - horse | thymoglobulin - rabbit
124
Antithymocyte globulin ADE
infusion reaction - pre-medicate (benadryl, APAP, steroids)
125
Prednisone ADEs that I forget (3)
osteoporosis fluid retention acne
126
Antiproliferate agents
Mycophenolate Mofetil Mycophenolic acid Azathioprine
127
ADEs of mycophenolate
spontaneous abortion GI upset lymphoma take on EMPTY STOMACH
128
azathioprine pharmacogenomics
TPMT deficiency - increased myelosuppression
129
Calcineurin inhbitors
tacrolimus (Prograf) | Cyclosporine (NEoral, Gengraf, Sandimmune)
130
ADEs if calcineurin inhibitors
QT prolongation Neurotoxicity Lymphoma Increased lymphoma
131
Cyclosporine ADEs
``` Hirsutisim Gingival hyperplasia Neurotoxicity Edema Lymphoma low Mg ```
132
Which cyclosporine brands have better bioavailability?
Gengraf | Neoral
133
MTOR Kinase inhibitors
Everolimus | Sirolimus
134
Everolimus ADEs
edema | HTN
135
Sirolimus ADEs
increased lipids/BS | irreversible pneumonia/cough
136
Everolimus should not be used for __ days post-transplant
30 days
137
Belatacept MOA
CD80/CD86 blockade - blocks T cell production of inflammatory molecules
138
Belatacept can only be used if patients is ___ positive
EBV+
139
Risk with belatacept
post-transplant lymphproliferative disorder
140
Which of the tranpslant meds can cause DM
Tacrolimus steroids cyclosporine
141
Which of the transplant meds increase lipids
mTOR steroid cyclosporine
142
which of the transplant meds increase BP
cyclosporine | tacrolimus
143
Primary PPX for PCP Toxoplasma MAC
PCP: Bactrim (<200) Toxo: Bactrim (<100) MAC: azithromycin weekly (<50)
144
Second-line primary PPX for PCP/taxo
PCP: Dapsone (pyrimethamine + leucovorin) Toxo: Dapsone + pyrimethamine + leucovorin
145
How long to do MAC?
3 months on ART and CD4>100
146
How long on PCP/toxo PPX?
3 months with CD4 above 200
147
Treatment of candidiasis
1. fluconazole | 2. itraconazole
148
Treatment of cryptococcal meningitis
1. ampho B + flucytosine 2. Fluconazole + flucytosine secondary ppx: fluconazole
149
Treatment of CMV
1. valganciclovir/ganciclovir | 2. cidofovir/foscarnet
150
Treatment of MAC
ethambutol + macrolide | Continue for secondary ppx
151
Treatment of PCP
1. Bactrim 2. Petamidine Secondary ppx: Bactrim or dapsone
152
Treatment of toxoplasmosis
1. pyrimethamine + leucovorine + sulfadiazine 2. Bactrim secondary ppx: same as tx
153
UC v Crohn's Which is deep? Which is at colon/rectum? Which is continuous?
``` UC - superficial CD- deep UC - colon/rectum CD - throughout GI UC - continuous Crohn's - non-continuous ```
154
Probitics useful for UC/CD?
Yup
155
Treatment for acute exacerbation
steroids
156
Which steroids available rectally?
budesonide and hydrocortisone | for UC only!
157
Uceris
budesonide - for UC
158
Entocort
budesonide - for CD
159
Azulfidine
sulfasalazine
160
Aminosalicylates for UC or CD?
UC
161
When to use rectal aminosalicylate?
If localized to distal UC
162
ADEs of sulfasalazine
HSR | Yellow/orange skin
163
Giazo
Balsalazide | MALES ONLY
164
Colazol ADE
stains teeth if chewed (think Colgate)
165
Thiopurine ADEs
malignancy, hematologic toxicities | Myelosuppression with TPMT
166
MTX dosage forms
IM or SC
167
MTX for UC or CD?
CD
168
Cyclosporine for UC or CD?
UC
169
Anti-TNF agents for UC or CD? Which ones?
Both Golimuab Infliximab Adalimumab
170
Ustekinumab mechanism and use?
Anti-IL12/23 | CD who haven't tried anti-TNF
171
Tofacitinib mechanism and use?
JAK STAT | UC
172
Integrin antagonists - what drugs and what are they used for?
natalizumab - CD | Vedolizumab - CD/UC
173
Natalizumab ADE
PML
174
How long to continue integrin inhibitors/wait for response?
Natalizumab - 12 weeks | vedolizumab - 14 weeks
175
FMEA vs RCA?
FMEA - prospective | RCA - retrospective
176
Do not use abbreviations
u for unit IU MS/MgSO4/MSO4
177
Precautions with high-alert medications
Pre-mixed when possible Store in pharmacy (not on floor) Limit concentrations available
178
Contact precautions - for what bugs
MRSA and Cdif
179
How to reuce catheter infections
chlorhexidine and antibiotic impregnated central venous catheters
180
Is alcohol or soap/water better for cleaning hands?
Usually alcohol - unless CDIF
181
What drugs increase LDL (but not TG)
fibric acid SGLT2 inhibitors TZDs
182
Ezetimibe can decrease CV events in what patients?
with recent ACS
183
Who are the 4 statin benfit groups
LDL >190 Clinical ASCVD DM 40-75 years ASCVD risk >7.5%
184
What intensity of statin for DM?
>7.5% ASCVD risk - high | otherwise moderate
185
What intensity of statin for ASCVD risk >7.5% w/o diabetes?
moderate
186
Low intensity statins
``` Fluvastatin 20-40 Lovastatin 20 pravastatin 10-20 pitatavastatin 1 simvastatin 10 ```
187
Which statins have drug interactions?
Simvastatin Lovastatin Atorvastatin (not as much)
188
Which statins have to be taken in evening?
Simvastatin | Lovastatin
189
Which meds can increase myopathy with statins? (2)
Niacin | Colchicine
190
Cyclosporine can be used with what statin?
Rosuvastatin 5mg
191
Ezetimibe ADE
myalgias
192
Bile acid sequestrants ADEs
INCREASE TGs | Constipation/bloating/gas
193
Bile acid sequestrant indication
Decreases BS for DM!!
194
What is the DOC for hyperlipidemia in pregnancy?
colesevelam
195
Bile acid sequestrants can decrease absorption of ....?
``` ADEK everything else (separate from all drugs) ```
196
Fibrates mechanism
PPAR alpha activators
197
Fibrates effect on lipid profile
Decrease TG Decrease LDL (or increase if TG are high) Increase LDL
198
Fibrates ADEs
Dyspepsia, myopathy
199
Contraindications of fibrates
gallbladder disease | severe liver disease
200
Niacin other name
Vitamin D
201
Nian effect on lipid profile
Decrease LDL and Increase HDL
202
Which niacin has the least flushing?
IR
203
Niaspin ADEs
``` Flushing rhabdomyolysis hepatotoxicity Increase BS Increase Uric acid N/V/D ```
204
How to treat flushing from niacin?
aspirin
205
Which niacin has least hepatotoxicity?
Niaspan
206
Fish oil indication
TG >500
207
Which fish oil has no change in LDL
Vascepa | Lova increases it
208
PCSK9 inhibitors indications
familial hypercholesterenmia or clinical ASCVD
209
Praluent
alivocumab (PSCK9)
210
Repatha
Evolocumab (Repatha)
211
Mipomerson and lomitapide use
homozygous familiar hypercholestermia
212
Mipomerson and lomitapide have REMS - why?
liver disease
213
Welchol
Colesevalam
214
Antara
Fenofibrate
215
Lopid
Gemfibrozil
216
Where can find info about immunizations?
CDC Pink book Morbidity and mortality report
217
Which vaccines are live
``` Zostavax Yellow fever Tyhpoid Cholera MMR Varicella ```
218
IVIG and what issue with vaccines?
Separate from live vaccines - either 3 months before or 2 weeks after vaccine
219
What vaccine can cause false negative PPD?
Live
220
Contraindications to live vaccines?
Pregnancy | Immunosuppression
221
When to give TDaP in pregnancy?
weeks 27-36
222
Vaccines for asplenia
Hib, pneumococcal, menigococcal (encapsulated bacteria)
223
HIV CD4 <200 vaccine requirements
meningococcal Hib Hep b
224
Hep B is given when?
``` within 24 hours of birth CLD HC workers HIV DM ```
225
HPV indication (and how many based on age)
F: 9-26 M: 9-21 Give 2 doses if <15, 3 otherwise
226
Earliest age to give flu ?
6 months
227
Who needs 2 doses of flu?
anyone less than 8 who is getting the flu vaccine for the first time
228
What are the HD flu vaccines?
fluzone HD | FluAd
229
What is PICC?
Inserted into small vein and maneuvered into the vena cava
230
What meds are vesicants?
Vasopressors Anthracycline Vinka alkaloids
231
What is the problem with PVC containers?
Contain DEHP - leaches into solution
232
What meds can't be used with PVC?
``` Lorazepam Amiodarone Taxanes Tacrolimus Insulin Nitroglycerin ```
233
What IV meds require NS?
``` Ampicillin Daptomycin Infliximab Amp/sul Caspofungin Ertapenem Phenytoin ```
234
D5W only
Bactrim Oxalaplatin Amphoterrible Synercid
235
Ceftriaxone is incomptible with???
calcium!
236
What meds require a filter
``` Golimumab amiodarone lorazepam phenytoin lipids (1.2) ampho b taxanes GAL PLAT ```
237
What 2 meds should not be fridge?
Phenytoin | Furosemide
238
What meds should be protected from light during administration
``` Doxycycline Epoprostenol Micafungin Nitroprusside Phytanodione ```
239
What med turns blue when toxic?
Nitroprusside
240
What med turns pink but is not toxic?
Dobutamine
241
What drug turns urine blue?
mitoxantrone
242
What flu vaccine is egg free?
FluBlok
243
What age can get FluMist?
2-49
244
Which meds stored in freezer?
MMRV zostavax varicella
245
Rotavirus is live or nah?
Livee
246
Varivax and zostavax are contraindicated with??
gelatin | neomycin
247
Antivirals can get in the way of reaction to what vaccine?
Live vaccines - varivax and zostavax
248
ROA of varivax and zostavax?
subcutaneous
249
Typhoid oral vaccine storage
Refrigerate
250
Yellow fever vaccine allergies
egg, gelatin
251
Cholera storage
freezer
252
How long to keep temperature logs
3 years
253
Which vaccines need freezed?
MMRV zostavax varicella cholera
254
Risk of using antidepressants in bipolar disorder?
can cause mania
255
acute treatment of bipolar disorder - mania
valproate | lithium + antipsychotic
256
acute treatment of bipolar disorder - depression
lithium | lamotrigine
257
preferred for BPD in depression
latuda | lamotrigine
258
carbamazepine for mania or depression
mania
259
can antipsychotics be used as monotherapy for bpd
no
260
lithium goal monitoring
0.6-1.2mEq/L (trough0
261
ADEs of lithium
``` GI upset cognitive effects Cogwheel rigidity Tremor Increased weight Polyuria Hypothyroidism ```
262
Toxicity of lithium
>1.5: tremor, vomiting/D, confusion, ataxia | >2.5: arrhythmia, sz, CNS depression
263
How is lithium cleared?
RENAL
264
Lithium Drug interactions
Serotonergic Clearance - diuretics, ACE/ARB increase levels SALT intake matters a lot
265
OTC self-treatment for insomnia
Doxylamine | Diphenhydramine
266
What drugs help with just falling asleep
Ramelteon | Zaleplon
267
What drugs help with just staying asleep
Doxepin | Suvorexant
268
what drugs help with falling asleep and staying asleep
zolpidem | eszopiclone
269
Schedule of all the sleep meds (benzos, Z-drugs, orexin)
CIV
270
ADEs of non-benzo sleep meds
ataxia | parasomnias
271
zolpidem DF
Edluar (SL) | Intermezzo (SL)
272
Suvorexant MOA
Orexin antagonist
273
Which benzos preferred for sleep
Lorazepam | Temazepam
274
How to treat RLS??
Dopamine agonists (pramipexole, ropinirole) 1-3 hours before bed OR gabapentin
275
ADEs of dopamine agonists
orthostasis and somonlence
276
Narcolepsy treatment
Modafinil Armodafinil Sodium oxybate
277
Schedule of stimulants for narcolepsy
CIV
278
Schedule of sodium oxybate
CIII (date rape drug -REMS)
279
Osmolarity equation
mOsm/L = Wt (g/L)/MW x * of particles * 1000
280
kalories in carbs
3.4kcal/g
281
calories in fat (EN)
9kcal/g
282
calories in protein
4kcal/g
283
calores in PN fat emulsions
10%: 1.1kcal/mL 20%: 2kcal/mL 30%: 3kcal/ML
284
``` Max lifetime dose of Bleomycin Doxycycline vincristine cisplatin ```
Bleomycin: 400 units Doxycycline: 450-550mg/m2 Vincristine: 2mg at one time Cisplatin: 100mg/m2 per cycle
285
What chemo drugs don't cause myelosuppression?
vincristine pegasparaginase bleomycin
286
which drugs cause lots of N/V
Platinums cyclophosphamide ifosfamide
287
Mucositosis drugs
``` 5-FU MTX capecitabine irinotecan -nibs ```
288
What chemo drugs cause QT prolongation
arsenic trioxide | TKIs
289
What chemo drugs cause pulmonary fibrosis
busulfan | carmustine/lomustine
290
What chemos cause neuropathy
vinka alkaloids taxanes platinums
291
What chemos cause hemorrhagic cystitis
cyclophosphamide ifosfamide (prevent with Mesna)
292
What drugs cause nephrotoxicity
MTX | Cisplatin (prevent with amifostene)
293
What drugs cause thromboembolism
SERMs aramatose inhibitors thalidomides
294
Zinecard
dexrazoxane for cardioprotection
295
Tocect
Dexrazoxane for extravasation
296
Uridine triacetal - antidote fr what?
5-FU | capecitabine
297
Glucarparidase - antidoate for what?
MTX
298
Dolasetron ADE
QT prolongation (no IV administration)
299
Sancuso
granisetron patch
300
Decadron
dexamethasone
301
Drugs that cause hand-foot syndrome
Capecitabine 5-FU liposomal doxorubicin cytarabine
302
Hypercalcemia of malginancy treatment
calcitonin loops/hydration xgeva, zometa
303
Vesicant chemo drugs
vinka alkaloids | anthracyclines
304
Which vesicants should have warm compress?
vinka alkaloids anthracyclines (the rest use cold)
305
How to treat vincristine extravastation
Hyaluronidase | and warm compress
306
``` Max lifetime dose of Bleomycin Doxycycline vincristine cisplatin ```
Bleomycin: 400 units Doxycycline: 450-550mg/m2 Vincristine: 2mg at one time Cisplatin: 100mg/m2 per cycle
307
What chemo drugs don't cause myelosuppression?
vincristine pegasparaginase bleomycin
308
which drugs cause lots of N/V
Platinums cyclophosphamide ifosfamide
309
Mucositosis drugs
``` 5-FU MTX capecitabine irinotecan -nibs ```
310
What chemo drugs cause QT prolongation
arsenic trioxide | TKIs
311
What chemo drugs cause pulmonary fibrosis
busulfan | carmustine/lomustine
312
What chemos cause neuropathy
vinka alkaloids taxanes platinums
313
What chemos cause hemorrhagic cystitis
cyclophosphamide ifosfamide (prevent with Mesna)
314
What drugs cause nephrotoxicity
MTX | Cisplatin (prevent with amifostene)
315
What drugs cause thromboembolism
SERMs aramatose inhibitors thalidomides
316
Zinecard
dexrazoxane for cardioprotection
317
Tocect
Dexrazoxane for extravasation
318
Uridine triacetal - antidote fr what?
5-FU | capecitabine
319
Glucarparidase - antidoate for what?
MTX
320
Dolasetron ADE
QT prolongation (no IV administration)
321
Sancuso
granisetron patch
322
Decadron
dexamethasone
323
Drugs that cause hand-foot syndrome
Capecitabine 5-FU liposomal doxorubicin cytarabine
324
Hypercalcemia of malginancy treatment
calcitonin loops/hydration xgeva, zometa
325
Vesicant chemo drugs
vinka alkaloids | anthracyclines
326
Which vesicants should have warm compress?
vinka alkaloids anthracyclines (the rest use cold)
327
How to treat vincristine extravastation
Hyaluronidase | and warm compress

NAPLEX D: (3 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions