The elderly Flashcards

(41 cards)

1
Q

What is frailty

A

Reduced ability to withstand illness without loss of function

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2
Q

What is ageing

A

Progressive accumulation of damage to complex system resulting in aggregate loss of system redundancy

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3
Q

What is frailty phenotype?

A
3 of 5 criteria
Unintentional weight loss
exhaustion
Weak grip strength
Slow walking speed
Low physical activity
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4
Q

What is HIS think frailty?

A
Functional impairment 
Resident in care home
Acute confusion
Immobility or falls
List of 6+ medicines
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5
Q

What are examples of health domains?

A
Medical
Psychological
Functional
Behavioural
Nutritional 
Spiritual 
Social
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6
Q

What is a comprehensive geriatric assessment

A

Process to assess and manage illness in older people with frailty

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7
Q

What are key features of delirium?

A

Disturbed consciousness
Change in cognition
Acute onset and fluctuant

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8
Q

What are the consequences of delirium?

A

Increased risk of death, longer stay, increased institutionalisation, persistent functional problems

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9
Q

What precipitates delirium?

A
Infection
Dehydration
Biochemical disturbance
Pain
Drugs
Constipation/retention
Hypoxia
Alcohol/drug withdrawal
Sleep disturbance
Brain injury
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10
Q

How to treat delerium

A
Treat cause
Stop bad drugs
Usually no need for drug treatment of delirium 
Re-orientate and reassure agitated patients 
Correction of sensory impairment
Normalise sleep-wake cycle
Ensure continuity of care
Avoid catheterisation/venflons
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11
Q

What is dementia

A

Acquired decline in memory and other cognitive functions in an alert person sufficiently severe to cause function impairment and present for more than 6 months

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12
Q

Alzheimers features

A

Slow insidious onset
Loss of recent memory first
Progressive functional decline
RFs - age, vascular risk factors, genetics

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13
Q

Vascular dementia features

A

Step wise progression
Executive dysfunction may predominate
Gait problems
Often known vascular risk factors

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14
Q

Dementia with Lewy Bodies features

A

Link with parkinson’s
Very fluctuant
Hallucinations common
Falls common

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15
Q

Reversible causes of dementia

A
Hypothyroidism
Intracerebral bleed/tumours
B12 deficiency
Hypercalcaemia
Normal pressure hydrocephalus
Depression
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16
Q

Fronto-temporal dementia features

A

Onset at earlier age
Early symptoms different - behavioural change, language difficulties, memory early on not affected
Lack insight into difficulties

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17
Q

Management of dementia

A
Support for person and carers
Cognitive stimulation
Exercise
Music/light therapy
Cholinesterase inhibitors 
Antipsychotics - avoid if possible, start low go slow
18
Q

What is capacity/

A

Is patient capable of making decisions about their care
Do they have a legally appointed proxy decision maker
Do we/relatives know what their wishes would be

19
Q

Why do patients fall?

A

Intrinsic factors - Gait and balance problems, syncope, chronic disease, visual problems, acute illness,
Extrinsic factors - environmental hazards, poor lighting
Situational factors - medications, alcohol, urgency of micturition

20
Q

Assessment of gait and balance

A
Sitting to standing ability
Transfers
Static standing balance
Romberg test
Dynamic standing balance
Gait
21
Q

Causes of syncope

A

Situation syncope - acute haemorrhage, cough/sneeze, GI stimulation, micturition, post exercise
Orthostatic hypotension - autonomic failure, volume depletion (haemorrhage, diarrhoea, addison’s)
Cardiac arrhythmias - sinus node dysfunction, AV conduction disease, implanted device malfunction
Structural cardiac or cardiopulmonary disease
Cerebrovacular

22
Q

Question in a history assessing syncope?

A

Patient - Prodromal symptoms, loss of consciousness, last and first things they recall, previous episodes, injuries, PMH, FH, medications
Collateral - Circumstances of event, posture before LOC, appearance, movement?, tongue biting, Duration of event, confusion?, weakness?

23
Q

Examination in assessing syncope?

A

Vital signs - lying and standing blood pressure
Focussed neurological and cardio exam
Look for injuries

24
Q

Features of 12 lead ECG in syncope assessment?

A

Inappropriate, persistant bradycardia, Long QT, Abnormal T wave inversion

25
Red flags for syncope
``` ECG abnormality Heart failure Onset with exertion FH of sudden cardiac death/inherited cardiac condition New or unexplained dyspnoea Heart murmur ```
26
Features of a seizure
Seizure if 1 or more of Bitten tongue, head to 1 side, no memory, unusual posturing, prolonged jerking, confusion And not prodromal symptoms, sweating, precipitated by prolonged standing, pallor during episode
27
Causes of sarcopenia
``` Diabetes Elderly Chronic disease Lack of use Inflammation Nutritional deficit Endocrine ```
28
Effect of absorption of levodopa in elderly
Increased
29
Body composition changes in elderly
Reduced muscle mass Increased adipose tissue reduced body water
30
Effect of body composition changes on drug distribution i
Fat soluble drugs have increased distribution (diazepam, haloperidol) Water soluble drugs have decreased distribution, therefore increased serum levels (digoxin, atenolol, theophylline)
31
Protein binding changes in elderly
Decreased albumin there for decreased binding and increased serum levels of acidic drugs
32
Opioids in elderly
Lower doses needed
33
NSAIDs in elderly
Increased adverse effects renal impairment GI bleeding
34
Digoxin in elderly
Increased toxicity | Lower doses need
35
Diuretics in elderly
Reduced clearance
36
Antihypertensives in elderly
Exaggerated effects on BP and HR More likely issues with postural hypotension ACEi often pro-drugs not metabolised to active form Renal adverse effects
37
Anticoagulants in elderly
More sensitive to warfarin | greater risk from warfarin
38
Antibiotics in elderly
Increased adverse effects
39
Excretion in age
Renal function decreases | Reduced clearance, increases half life of many drugs
40
Pharmacodynamics in elderly
Increased sensitivity to particular medicines | DIazepam, warfarin
41
Metabolism in elderly
Toxicity due to reduced metabolism | Reduced first pass metabolism