Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Antibiotics > The Fluff > Flashcards

The Fluff Flashcards

(56 cards)

Start Studying
1
Q

Sulfonamide

A

-Toxoplasmosis
(Sulfadiazine + pyrazinaminde)
[Nucleic Acid Inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Sulfonamide Interaction

A
  • Warfarin

- P450 inhibition

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Sulfonamide Toxicity

A
  • Kernicterus

- Hematopietic Disorders

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

TMP/SMZ

A

-Broad spectrum combo
-UTI’s
-RTI’s caused by H.Flu
-S.pneumoiae
-Shigella
-PCP in AIDS
[Nucleic Acid Inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

TMP/SMZ Toxicity

A
  • Megaloblastosis
  • Leukopenia
  • Kernicterus
  • Hematopietic Disorders
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Fluroquinolone

Ciprofloxacin, Oxafloxacin, Norfloxacin

A

-UTI: P.aeruginosa
-Enteritis: salmonella, shigella, E.Coli, Campylobacter
[Nucleic Acid Inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Fluroquinolone Toxicity

A
  • limitation of caffeine breakdown: seizures

- CONTRAINDICATED: <18 or pregnant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Nalidixic Acid

A

-Older quinolone
-Uncomplicated UTI
[Nucleic Acid Inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Nalidixic Acid Toxicity

A

-DO NOT COMBINE with Nitrofurantion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Nitrofurantoin

A

-uncomplicated UTI
-DO NOT COMBINE with Nalidixic Acid
[Nucleic Acid Inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

PenG

A

[cell wall synthesis inhibitor]

  • Given parenteral
  • N.Meningitidis
  • S.pneumoniae
  • Syphilis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

PenG Toxicity

A

-Hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

PenV

A

-Same as PenG, but in oral form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Penicllinase-Resistant Penecillin

Methicillin, Oxacillin, Dicloxacillin

A

-S.aureus

[cell wall synthesis inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Penicliinase-Resistant Penecillin Toxicity

A

-Hypersensitivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ampicillin Use

A

-Given IV
-E.Coli
-H.Flu
-Strep.pneumo
-Listeria
[cell wall synthesis inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Amoxicillin

A

-Same as ampicillin, but in oral form

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Extended Spectrum Penecillins

Ticarcillin, Pipercillin, Mezlocillin

A

-Difficiult Gram (-)
-Proteus Mirabilis
-P.aeruginosa
-Serratia Marcescens
-Klabsiella pneumoniae
[cell wall synthesis inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Imipenem

A

-Serious infections of unknown origin

[cell wall synthesis inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

B-lactamase Inhibitors

Clavulanic Acid, Sulbactam

A

-Poor properties, use only in combination with other antibiotics
[cell wall synthesis inhibitor]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

1-G-Cephalasporins

Cephalaxin

A

[cell wall synthesis inhibitor]

  • Not often used
  • Community acquired skin infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

2-G-Cephalasporins

Cefuroxime

A

[cell wall synthesis inhibitor]

  • community acquired pneumonia
  • H.Flu
  • Klabsiella
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

3-G-Cephalasporins

Ceftriaxone, Cefotaxime

Study These Flashcards
A

-penetrates CNS
-Ghonorrhea
[cell wall synthesis inhibitor]

24
Q

Cephalasporin Toxicity

Study These Flashcards
A
  • Hypersensitivity
  • Pain on injection
  • Bleeding issues
  • CONTRAINDICATED in patients with previous anaphalixis
25
Vancomycin
[cell wall synthesis inhibitor] - MRSA - Enterococcus faecium - Pencillin-Resistant S.pneumoniae - C.difficile
26
Aminoglycosides
[inhibitor of protein synthesis] - moderate to severe Gram (-) aerobic infections - synergistic with B-lactams
27
Aminoglycoside Toxicity
- Neprho toxicity | - Ototoxicity
28
Tetracyclines | tetracycline, doxycycline, minocycline
-Cholera -RMSF -Lyme Disease -Brucellosis [inhibitor of protein synthesis]
29
Tetracycline Toxicity
- GI Irritation - Phototoxicity - CONTRAINDICATED in <18 or pregnant - Fanconi syndrome - Phototoxicity
30
Chloramphenicol
[inhibitor of protein synthesis] - serious infections when other antibiotics are contraindicated - penetrates CNS
31
Chloramphenicol Toxicity
- Aplastic anemia - Bone marrow depression - Gray baby syndrome
32
Macrolides | Azithromycin, Clarithromycin, Erythroymcin
``` [inhibitor of protein synthesis] -Legionnella -B.pertussis -Chlamydia trachomatis Mycoplasma pneumoniae ```
33
Macrolide Toxicity
- GI Distress | - Can potentiate effects of other drugs such as corticosteroids, cyclosporine, digoxin, warfarin
34
Clindamycin
[inhibitor of protein synthesis] - given orally - opportunistic infections associated with AIDS - Severe anerobic infections with B. fragilis
35
Clindamycin Toxicity
- GI Distress - Skin rashes - Hepatotoxicity - POSSIBLE C.DIFF SUPERINFECTION
36
Streptogramins | Dalfopristin, Quinupristin
[inhibitor of protein synthesis] - Penicillin resistant S.pneumonae - MRSA
37
Oxazolidinones | Linezolid
[inhibitor of protein synthesis] - Penicillin resistant S.pneumonae - MRSA - Group A&B Strep
38
Oxazolidinone Toxicity
- BRADYCARDIA - THROMBOCYTOPENIA - SUPERINFECTION
39
Metronidazole
[inhibitor of protein synthesis] - Pseudomembraneous cholitis caused by: * C.diff * B.fragilis * Giardia * Trichomoniasis
40
Metronidazole Toxicity
- Nausea - Headache - CONTRAINDICATED when there is a bun in the oven
41
Isoniazid
[antitubular] - Prophylaxis following TB exposure - Mycobacteria - Mainstay of TB regimen
42
Isoniazid Toxicity
-Hepatotoxicity
43
Rifampin
[antitubular] - TB - Prophylaxis for N.Meningitidis & H.flu
44
Rifampin Toxicity
-Hepatotoxicity
45
Ethambutol
[antitubular] | -TB
46
Ethambutol Toxicity
-Optic neuritis including Christmas (red/green) discrimination
47
Pyrazinamide
[antitubular] | -TB
48
Pyrazinamide Toxicity
Hepatotoxicity
49
TB Treatment Regimen
0-2mo: INH + Rifampin + Ethambutol + Pyrizinamide 2-6mo: INH + Rifampin + Ethambutol 6-10mo: INH + Rifampin
50
Mycobacterium Avium Complex (MAC)
For Life: Ethambutol + Azithromycin or Clarithromycin | For very low T counts: add Rifampin
51
Amphotericin B
[antifungal] - Cryptococcus Meningitis (+flucytosine) - Candida (+flucytosine) - Coccidioides
52
Amphotericin B Toxicity
- VERY VERY TOXIC - nephrotoxin - Hypokalemia - Hypersensitivity - Vomiting
53
5-Fluorocytosine | Flucytosine
[antifungal] - rarely used alone - Used with Amphotericin B
54
Azoles | Ketoconazole, Fluconazole, Itraconazole
``` [antifungal] -Blastomtcosis -Histoplasmosis -Candidasis -Cryptococcus Coccidiodial Meningitis ```
55
5-Fluorocytosine Toxicity
- Bone marrow depression - Hairloss - GI Distress
56
Azole Toxicity
- Vomiting - Diarrhea - Rash

Antibiotics (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions