The Fluid Mosaic Model of Membranes & Specific Functions of Membrane Proteins Flashcards

1
Q

What does this model imply?

A
  • Membranes are fluid
  • Substances are able to move within and through membranes in a fluid manner
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2
Q

What do cell membranes consist of?

A
  • Phospholipid bilayer
  • Proteins
  • Cholesterol
  • Glycolipids and glycoproteins
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3
Q

Phospholipid bilayer

A
  • A double layer of phospholipids made up of hydrophobic tails and hydrophilic heads
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4
Q

Two types of proteins

A
  • Peripheral Proteins
  • Integral Proteins
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5
Q

Peripheral Proteins

A
  • Found on either the external or internal surface of the membrane
  • They are hydrophilic
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6
Q

Integral Proteins

A
  • Also called transmembrane proteins
  • Span from the extracellular side to the intracellular side of the membrane
  • Mostly hydrophobic
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7
Q

Integral Channel Protein

A
  • They have a transport channel or tunnel in their centres
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8
Q

Cholestral

A
  • Steroid-based lipid
  • Gives the membrane flexibility
  • At low temps, keeps fluidity and prevents hardening
  • At high temps, maintains rigidity of membrane
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9
Q

Glycoproteins

A

Carbohydrate chains attached to proteins

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10
Q

Glycolipids

A

Carbohydrate chains attached to lipids

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11
Q

What do glycoproteins and glycolipids have in common?

A
  • Only found extracellulary
  • Act as surface-markers or fingerprints so that diff cells can be distinguished between
  • Not in plant cells
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12
Q

Specific Functions of Membrane-Proteins

A
  • Transport
  • Enzymatic Activity
  • Signal Transduction
  • Cell-to-cell recognition
  • Intercellular joining
  • Attachment to the cytoskeleton and extracellular matrix
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13
Q

Transport

A
  • Proteins act like hydrophilic channels
  • Also act like a shuttling mechanism to pump substances across membranes
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14
Q

Enzymatic Activity

A
  • Enzymes embedded in the membrane can have open active sites to catalyze processes
  • Enzymes can work together to produce important products for metabolic pathways
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15
Q

Signal Transduction

A

A membrane receptor protein can have binding sites for signalling molecules that allow the protein to relay the message along to the interior of the cell

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16
Q

Cell-to-cell recognition

A
  • Glycoproteins act like fingerprints so that other membrane proteins can recognize them
  • Temporary
17
Q

Intercellular Joining

A

Membrane proteins on adjacent cells can form attachments called gap junctions and tight junctions so the cells remain anchored together

18
Q

Attachment to the cytoskeleton and extracellular matrix

A
  • Membrane proteins can act like anchors for the cytoskeleton, so that cell shape and organelle location can be maintained
19
Q

ECF

A

Extra cellular fluid

20
Q

ICF

A

Intra cellular fluid