The Genetic Code Flashcards
(25 cards)
A sequence of three nucleotides called____ codes for a specific amino acid
triplet
Each triplet is called a
codon
Codons are written from the #___ ‘end ____ ‘end of the mRNA molecule
5’ end to the 3’
____ is a change in the nucleotide sequence in a molecule of DNA.
mutation
Some mutations are random, while others are caused by ____
mutagens
What mutation occurs when one or more nucleotides is/are lost from a DNA molecule.
deletion mutation
An_____ occurs when one or more nucleotides is/are added to a DNA molecule
insertion mutation
______ mutation has a negligible effect on the organism because the resulting amino acid is identical.
silent mutation
TRUE/FALES
mutation that produces a protein with one different amino acid usually has a small to moderate effect on the protein overall.
TRUE
When a mutation causes a protein deficiency or defective protein synthesis and this mutation is passed through generations, it is a ____
genetic disease
____ results from defective cyctic fibrosis transmembrane conductance regulator (CFTR); the effects are extremely thick lung mucus and low pancreatic secretions.
Cystic fibrosis
____ results from a deficiency of an enzyme needed for galactose metabolism and can cause mental retardation
Galactosemia
___ DNA is synthetic DNA that contains segments from more than one source.
Recombinant DNA
Three key elements are needed to form recombinant DNA:
- A DNA molecule
- An enzyme
- A gene
___ chain reaction (PCR) amplifies a specific portion of a DNA molecule, producing millions of exact copies.
Polymerase
Four elements are needed to amplify DNA by PCR
a segment of DNA, Two primers, DNA polymerase enzyme and, Nucleoside triphosphates
After each cycle the amount of DNA is ___, so after 20 cycles, 1,000,000 copies have been made
doubled
The DNA is first amplified by PCR, and then cut by restriction enzymes, TRUE/FALSE
TRUE
A virus with an RNA core is called a __
retrovirus
Retroviruses invade a host and then synthesize viral DNA by ___
reverse transcription
The viral DNA can then transcribe RNA, which then directs ____(new retroviral particles to infect other cells).
protein synthesis
Two causes of mutation disease call
Spontaneous and induced mutation
Induced Mutation caused by
Environment
Deletion meaning
Missing pieces