The Human Microbiome- Lecture 10/4/21

Question 1

Human Microbiome (eco def)

Answer 1

The community of microbiota inhabiting our bodies

Question 2

Human Microbiome (Genetic def)

Answer 2

The collective genome of all of the microbiota inhabiting our bodies

Question 3

Human Microbiota

Answer 3

All of the microbes inhabiting our body

Question 4

Colonized sites (6)

Answer 4

Nares
Oral cavity
Skin
Small intestine
Proximal colon
Distal colon

Question 5

Maybe colonized site

Answer 5

Stomach (in some people)

Question 6

Not colonized spots

Answer 6

Blood

CNS/spinal fluid

Question 7

Functions of our symbiotic gut Microbiome (3)

Answer 7

-Metabolic
-Immune and structural
Protective

Question 8

Dysbiosis of microbiota

Answer 8

Associated with a wide variety of diseases

Question 9

Sterile mouse

Answer 9

NO microbiome

Question 10

Infants first exposure to microbes

Answer 10

Controversial, possibly birth and breast feeding

Question 11

Bifidobacteria

Answer 11

Found in breast milk, thought to be first colonizer, helps baby digest complex sugars

Question 12

Hygiene hypothesis

Answer 12

Growing up in too sterile an environment may cause dysbiota

Question 13

Other causes of dysbiota (2)

Answer 13

• Western lifestyle

- Abx usage

Question 14

Curing dysbiota (4)

Answer 14

• Diet
• Prebiotics
• Probiotics
• Fecal microbiota transplant