The limbic system Flashcards

(30 cards)

1
Q

what is the function of the limbic system

A

emotion, appetite and homeostasis - endocrine and autonomic nervous system control, memory function and recall, olfaction

engages the person with the environment, reference to past experience, present situation

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2
Q

what is the limbic system

A

interconnected discrete structures within the brain and brain stem forming a ring around the corpus callosum

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3
Q

what four catergories can the limbic system functions be divided into

A

emotions and drives via the amygdala

homeostasis and motivation (hypothalamus)

olfaction (olfactory cortex)

memory (hippocampus)

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4
Q

where is the amagdala

A

found at the anterior tip of the hippocampus, provides and emotional component to experiences and memory and teh ability to recognise fear

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5
Q

what inputs go to the amygdala

A

frontal temporal and parietal lobes receiving cognitive information

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6
Q

what are the efferents from the limbic system

A

hypothalamus and limbic cortex providing and emotional cognisance, and visceral/ homeostatic information

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7
Q

what can amygdala lesions cause

A

loss of recognition of fear and anger in other people

stimulation causes fear and aggression

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8
Q

what is Kluver-bucy syndrom

A

bilateral temporal lobe lesions (including the amagdala) in all mammals produces

visual recognition impairments

hypersexuality

loss of fear conditioning

oral tendencies

flattened emotions

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9
Q

describe hypothalamic circuitry

A

parasympathetic to viscera

sympathetic

feedbacks to the limbic system about environments both internally and externally

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10
Q

what subgroups can effects of the hypothalamus be broken into

A

vegetive (visceral)

endocrine (control over anterior pituritary release

behavioural functions

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11
Q

what is the mesolimbic dopamine system

A

reward system

found in the ventral tegmental area of the midbrain

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12
Q

where does the mesolimbic dopamine system project to

A

medial prefrontal cortex, amygdala, hippocampus, nucleus accumbens, ventral pallidum

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13
Q

describe the effects of recreational drugs on the limbic system

A

thought to have a common dopaminergic pathway in the limbic system

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14
Q

what is the anterior insular cortex

A

provides introspeciton which allows the interpretation of sensation as joy or disgsust

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15
Q

what is huntigntons

A

a progressive frontal cortex degenerative disease

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16
Q

what is the periaquaductal grey

A

the primary control centre for descending pain modulation

encaphalin producing cells which suppress pain

The PAG is able to reduce activity in the
ascending pain pathway

17
Q

describe the limbic system’s effect on pain

A

involved in pain perception such as the PAG

18
Q

what chemicals agonise the effect of PAG on pain

A

opiates and endorphins

19
Q

what can electrical stimulation of PAG cause

20
Q

what is the effect of nalaxone

A

blocks opiate receptors- used to counteract opiate pain medications

21
Q

what limbic structures are involved in depression

A

ventromedial portion of the prefrontal cortex

cingulate gyrus

22
Q

what is the ventromedial portion of the prefrontal cortex

A

goal setting, forward planning and ascribing meaning to perception

reduced mass in individuals with familial depression

23
Q

describe the state of the ventromedial portion of the prefrontal cortex in bipolar disorder

A

inactive during depressive states

hyperactive during manic phases

24
Q

what is the function of the cingulate gyrus

A

involved in emotion and cognition

25
describe the state of the cingulate gyrus in mental illness
reduced during depression more active in depressive phases of bipolar patients and less active in manic phases involved in schizophrenia, mood swings
26
what neurotransmitters may be imbalanced in depression
serotonin, dopamine, norepinephrine
27
what hormone is elevated as a response to prolonged stress
glucocorticoid, released from the adrenal glands
28
what part of the brain detects glucocorticoid
hippocampus which then activates the hypothalamus into releasing corticotropin releasing hormone
29
what hormone does corticotropin releasing hormon release
adrenocorticotrophic hormone which causes the release of more glucocorticoids
30
why may glucocorticoids be elevated in people with depression
cortical receptors feedback which blocks the production of CRH but this may not work this affects serotonin receptors