the male Flashcards

(31 cards)

1
Q

what is the role of the epididymis

A

sperm maturation

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2
Q

what is the role of the seminiferous tubules

A

sperm production

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3
Q

what is the purpose of the myoid cells that surround the seminiferous tubules

A

they provide a squeezing action that helps to move sperm

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4
Q

what cells are in the spaces between the seminiferous tubules

A

leydig cells

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5
Q

where does the biosynthesis of testosterone occur

A

in leading cells

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6
Q

where does the conversion of testosterone to dihydrotestosterone take place

A

in the Sertoli cells in the seminiferous tubules

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7
Q

how are steroid receptors transcription factors

A

steroid receptors have 2 binding sites one for the steroid and one for dna. blinding of the steroidal ligand acetic on the dna and alters the genes being expressed by target cells

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8
Q

where are androgen receptors expressed

A

epididymis, accessory glands, tissues where 2ndary characteristics appear

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9
Q

where is GnRH stored

A

hypothalamus

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10
Q

where is FSH and LH stored

A

anterior pituitary

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11
Q

how is GnRH released

A

pulsate release at a constant frequency

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12
Q

where is the FSH receptor located

A

on the Sertoli cell

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13
Q

where is the LH receptor located

A

on the leydig cell

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14
Q

how does FSH contribute to spermatogenesis, sperm maturation and hyoid cell contractility

A

androgen binding protein binds to T and DHT and concentrates them in the luminal fluids which stimulates the above

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15
Q

what enzyme converts T to DHT

A

5 alpha reductase

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16
Q

by what mechanism is GnRH secretion and LH and FSH inhibited

A

negative feedback with testosterone and inhibin

17
Q

where is the sperms initial ability to swim

A

in the epididymis

18
Q

what is the average vol of ejaculate

19
Q

what is the average sperm count

20
Q

what percent of sperm are still motile 1h after ejculation

21
Q

what percent of sperm are still motile 3h after ejac

22
Q

ph of sperm

23
Q

what makes up most of the ejaculate volume

A

seminal vesicle secretion (46-80%)

24
Q

what is an erection

A

erectile tissue becoming engorged with blood

25
what nervous system is ejaculation controlled by
sympathetic
26
causes of erectile dysfunction
drugs e.g. beta blockers, psychogenic, neurogenic, vascular, endocrine.
27
treatment of erectile dysfunction
prostaglandin E1 - aloprostadil | e5 - sildenafil
28
risk factors for prostate cancer
age, ethnicity, family history
29
symptoms of prostate cancer
urgent and frequent urination, nocturnal enuresis, difficulty starting or emptying, weak flow, interrupted, pelvic/back pain
30
management of prostate cancer
GnRH agonists and antagonists, androgen antagonist, 5 alpha reductase inhibitors
31
contraception in males
exogenous testosterone lowers fsh and lh