the structure of the liver Flashcards

1
Q

what is a hepatocyte

A

Liver cell

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2
Q

why is it crucial for the liver to have a good supply of blood

A

Because it carrys out many metabolic reactions

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3
Q

why is it necessary for the liver to have a good supply of oxygen

A

For aerobic respiration, as liver cells are very active therefore they require lots of ATP for active metabolic processes

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4
Q

what does the hepatic artery do

A

transport oxygenated blood from the heart to the liver

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5
Q

what does the hepatic portal vein do

A

Removes deoxygenated blood from the digestive system to the liver

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6
Q

how does blood leave the liver

A

leaves the liver through the hepatic vein (central vein)

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7
Q

what is the difference between the hepatic portal vein and hepatic vein

A

Hepatic portal vein- allows blood to enter the liver

Hepatic vein- allows blood to leave the liver

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8
Q

what artery does the hepatic vein join to in order for the blood to enter the heart from the liver

A

The hepatic vein joins to the vena cava

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9
Q

what is the bile duct

A

a tube connected to the liver

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10
Q

what is an advantage for the liver, by the blood recieved from the hepatic portal vein

A

it sends deoxygenated blood from the digestive system to the liver.
This allows the liver to absorb nutrients from the blood from the digestive system

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11
Q

what are some functions of the bile duct

A

carries bile from liver to the gall bladder for storage

contains excretory products such as bile pigments which leave in faeces

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12
Q

what is one example of as bile pigment

A

Bilirubin

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13
Q

Describe the internal structure of the liver

A

divided into lobes and lobules

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14
Q

what is smaller lobes or lobues

A

Lobules

As the liver is divided into lobes and further divided into lobules

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15
Q

what shape are lobules

A

Cylindrical

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16
Q

what does the meaning interlobal vessels mean

A

the hepatic artery and portal vein split into small vessels in the liver, which RUN PARALLEL TO LOBULES

17
Q

what cell is the liver mainly made of

A

hepatocytes

18
Q

what is a sinusoid

A

a space in the lobule where blood from HA and HPV mixes to increase oxygen content for hepatocytes

19
Q

why do hepatocytes have a large surface area

A

maximises rate of exchange of substances

20
Q

what cells coat the sinusoid

A

endothelial cells

21
Q

what is a kupffer cell

A

a specialised macrophage

22
Q

where are kupffer cells located

A

in the sinusoid

23
Q

what is the function of the kupffer cells

A

to breakdown and recycle old erythrocytes

24
Q

Kupffer cells breakdown red blood cells, what can this create

A

Bilirubin (bile pigment), product of a broken down haemoglobin

25
what type of substance is bilirubin
Bile pigment
26
what is the bile canaliculi
bile drains into this space, the canaliculi then drains bile into the bile duct
27
how does the bile duct form
bile made in liver released into bile canaliculi. The bile canaliculi join and form bile duct
28
what has the job of transporting bile to the gall bladder
Bile duct
29
why may blood in the hepatic vein have toxins
Because the deoxygenated blood has came from the digestive system where concentrations of substances are uncontrolled.
30
what is in the centre of a lobule
The centre of a lobule is a hepatic vein
31
where do sinusoids empty their blood
Into the centre of a lobule
32
name two differences between excretion and secretion
excretion can be - metabolic waste, e.g. urea Secretion is useful products, e.g. hormones, enzymes, bile salt excretion doesnt use vesicles secretion uses vesicles
33
what is one similarity between excretion and secretion other than they both use ATP
they are both involved in homeostasis
34
why are blood concentrations in the blood from hepatic portal vein uncontrolled and rich in products
because the blood has came from the digestive system, thereore rich in products
35
what process controls the concentration of blood in liver before entering the central vein
blood flowing in sinusoid, lined with hepatocytes which remove substances from blood when contact between the two is close