Theme 6b Cellular Recognition Flashcards

1
Q

Syngeneic

A

identical at all genetic loci

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2
Q

Congenic

A

genetically identical except at a single genetic region.

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3
Q

Where do most MHC amino acid differences occur in the molecule?

A

at the groove sites.

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4
Q

MHC variability on viral disease

A

in HIV certain HLA-B haplotypes are associated with slow disease progression, while others are associated with worse clinical outcomes.

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