Therapeutic drug levels Flashcards
(10 cards)
1
Q
Carbamazepine
A
4-12
2
Q
Digoxin
A
0.8-2 (AF)
0.5- 0.9 (HF)
3
Q
Gentamicin, Tobramycin
A
Peak 5-10
Trough < 2
4
Q
Lithium
A
0.6- 1.2 (up to 1.5 for acute symptoms), drawn as a trough
5
Q
Phenytoin/ Fosphenytoin
A
10- 20, if albumin low, calculate corrected level
Free Phenytoin 1-2
6
Q
Procainamide
A
4-10
NAPA (active metabolite) 15-25
Combined 10-30
7
Q
Theophylline
A
5-15
8
Q
Valproic acid
A
50-100 (up to 150 in some pts)
9
Q
Vancomycin
A
Serious infections (pneumonia, endocarditis, osteomyelitis, meningitis, bacteremia) AUC/MIC ratio 400-600 or trough 15-20
Other infections trough 10-25
10
Q
Warfarin
A
INR goal for most indications 2-3
Mechanical mitral valves 2.5- 3.5
