therapeutic ranges

Question 1

Gentamicin

Answer 1

MDR- peak (1h post dose) should be 5-10mg/L, trough should be less than 2mg/L
endocarditis- peak 3-5mg/L, trough less than 1mg/L

Question 2

Amikacin

Answer 2

MDR- peak (1h post dose) should be less than 30mg/L, trough less than 10mg/L
ODR- pre dose should be less than 5mg/L

Question 3

Streptomycin

Answer 3

peak 15-40mg/L, trough less than 5mg/L (or less than 1 in renal impairment or over 50s)

Question 4

Tobramycin

Answer 4

peak less than 10mg/L, trough should be less than 2mg/L

Question 5

chloramphenicol (elderly)

Answer 5

peak (2h post dose) 10-25mg/L, trough less than 15mg/L

Question 6

Ethambutol

Answer 6

peak (2-2.5 h after dose) 2-6mg/L trough should be less than 1mg/L

Question 7

Vancomycin

Answer 7

trough 10-20
trough 15-20 if MIC > 1mg/L