Thermoregulation in normal and extreme environments Flashcards

(51 cards)

1
Q

Many of the metabolic processes

essential to life produce ?

A

HEAT.

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2
Q

To maintain a constant body
temperature this HEAT must be
lost to the environment at a rate of?

A

that equals its production.

heat gain = heat loss

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3
Q

4 ways of Heat Gain

A
Conduction
e.g. touching a hot object
Convection
e.g. from a fan heater
Metabolism
e.g. basal, digestion, exercise
Radiation
e.g. from the sun
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4
Q

4 ways of Heat Loss

A
Conduction
e.g. touching a cold object
Convection
e.g. blood flow to skin
Evaporation
e.g. sweat
Radiation
e.g. skin to environment
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5
Q

rate of heat production is proportional to

A

metabolic rate

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6
Q

• Heat is

A

a spontaneous flow of energy from one object to
another caused by a difference in temperature between the
two objects.

Temperature is not heat

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7
Q

• Heat exists only as

A

energy in transit from one object to

another.

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8
Q

• When heat energy is added to a system, it is stored as

A

kinetic

energy of the atoms and molecules making up the system.

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9
Q

The Heat-Balance Equation

A

[metabolism (energy gained)– work (energy lost) ] - (heat loss) = storage of heat (Hs)

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10
Q

Storage heat formula:

A

Hstorage = ctissue .x massbody .x ΔTempbody

c= specific heat capacity
is the amount of heat energy required to raise the
temperature of 1kg mass by 1 Kelvin

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11
Q
1. Conduction
• Heat energy is transferred through a
solid, liquid or gas by direct \_\_\_\_\_
• Under normal circumstances, heat
gain or loss by conduction is \_\_\_\_\_
• Depends on the thermal
\_\_\_\_\_\_\_of the materials in
contact
A

contact
minimal
conductivity

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12
Q
  1. Convection
    • Convection transfers heat by
    fluid movement driven by a
    __________
    Transfer of heat from skin to fluid (air or H2O) warms the fluid,
    thereby reducing its ______; it rises and is replaced by cooler
    fluid.
    • Air has a low specific heat capacity. It warms rapidly, establishing ______-currents.
    _______impedes convection
A

temperature gradient
density
convection
Clothing

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13
Q

Conduction eqn

A

Hcond. = κcond.A.(T2 – T1)
Heat transfer is dependent on thermal conductivity and the temp.
difference between the two objects

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14
Q

Convection eqn

A

Hconv. = κconv.A.(T2 – T1) .
κconv. Is the convection coefficient W m-2 K-1
A = surface area
T = temperature of object 1 and 2

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15
Q

Higher wind speeds ______convective heat loss
and the ‘_____’ temperature is lower than the
‘ambient/air’ temperature

A

increase

apparent

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16
Q
  1. Evaporation
    •Heat is continually transferred to
    the environment as water is
    vapourized from the ______
    passages & the ____surface.
    Evaporative heat transfer is dependent on the __________________ between the solution and the environment
    (Note: partial pressure is dependent on temperature)
A

respiratory
skin
water vapor pressure gradient

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17
Q

Evaporation eqn

A

Hevap. = ĸevap.A.(P2 – P1)
Where:
• ĸevaporation = evaporation coefficient (W m-2 kPa-1)
• A = surface area available for heat exchange
• P = partial pressure of the evaporating fluid (usually H2O)
at a specified temperature (kPa)
.

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18
Q

The body has 2-4 million ____ ______throughout the surface.
• These eccrine glands are controlled by _______nerves &
secrete large quantities of weakly saline solution (hypotonic 0.2 – 0.4% NaCl).
• Cooling effect occurs as sweat evaporates.

A

sweat glands

cholinergic

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19
Q
4. Radiation:
• Radiation is the transfer of
\_\_\_\_\_\_\_energy by means
of \_\_\_\_\_\_\_\_waves
(infrared).
• Radiation heat transfer
does NOT require a?
A

thermal
electromagnetic
material medium

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20
Q

4 physiological modes of thermoregulation (effectors):

A
  1. metabolism
  2. vasomotor regulation (blood flow)
  3. sweating
  4. shivering
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21
Q

2 main Thermal regions

A
Core temperature - tightly
maintained
• Shell or skin temperature - highly
variable
• The core expands in a hot
environment and contracts in a
cold environment.
• Changes to the shell vary the
thickness of the ‘insulation’
22
Q

• Mean body temperature MBT eqn

A

MBT = 0.64Tcore + 0.36Tshell

23
Q

In females, core
temperature fluctuates with
the ?

A

menstrual cycle:
• hormone levels
• endometrial thickness
• ovulation

24
Q

Where is Heat Produced?
At Rest:
During Exercise:

A

primarily brain, heart,
liver and kidneys
primarily skeletal
muscles

25
Where is Heat Produced?
``` Overwhelmingly through the skin, via: Radiation Conduction Convection & Evaporation ```
26
At normal ambient temperatures 50 – 65 % of the heat of metabolism is lost by ___, with most of the remainder lost by evaporation. In a cold environment, _______is the major source of heat loss (blood flow to the skin ↓s to prevent this)
radiation | convection
27
Insulation of the shell Qualitative Variation: Quantitative Variation:
``` (vary the medium) • Fat (κcond = 1/3) • Feathers • Fur/Hair • Behavioural (clothing) ``` ``` (vary the thickness) • “Winter fat” • Piloerection (air-trapping) • Variable blood-flow to the skin (vasodilation & vasoconstriction) ```
28
``` Thermoregulatory Control Feedback System Receptors Controller (Integrator) Effectors ```
``` R- SKIN, BRAIN C- Hypothalamus E-1 Metabolism 2. Vasomotor 3. Sweating 4. Shivering ```
29
``` Temperature sensors - receptors Unlike many Negative Feedback Systems, there are two distinct types of peripheral (skin) sensors: ```
``` Warm Receptors & Cold Receptors. Afferents from these receptors project to the pre-optic hypothalamus ```
30
Process of regulation of Heat transfer
``` Peripheral (skin) thermoreceptors, core thermoreceptors • Input signal compared with ‘set point’ • Effectors: shivering, vasomotor, sweat • Activate/deactivate heat transfer ```
31
Metabolism Effector location
-Brown adipose | tissue, Mainly in newborns
32
Vasomotor Effector location
Blood vessels Vasoconstriction at skin, vasodilation at core = heat retention
33
Sweat Effector location
Increased sweat leads to evaporative heat loss in dry environments
34
Shivering Effector location
Increases metabolic heat | production
35
Piloerection Effector location
Traps a layer of air between skin | and hair = insulation
36
``` Metabolic heat gain: brown adipose tissue ‘brown fat’ high density of ? situated close to ? ```
• Newborn humans & hibernating animals (possibly also sig. adult humans) • High density of mitochondria for high level of metabolic activity • Situated close to blood vessels so that heat produced by metabolism of fatty acids can be quickly distributed to the rest of the body
37
How is heat transferred | within the body?
Conduction | Advection/Convection
38
Conduction speed? | Advection/Convection speed?
Conduction: SLOW | Advection/Convection: FAST
39
Heat transfer through vasodilation To remove heat produced by metabolism, ______is the primary mode of heat loss
convection | vasodiation
40
Hyperthermia of exercise | At the onset of exercise:
``` heat gain > heat loss = ↑ Tcore The hypothalamic integrator: Tcore ≠ Tset = “error” Neural output to activate heat loss via skin blood flow and sweating When heat loss = heat gain storage of heat decreases to zero But the elevated Tcore persists as long as exercise is maintained. ```
41
Heat stroke – a medical emergency
• Occurs when the thermoregulatory system fails and core temperature increases to 41°C or above • Excessive vasodilation at skin causes drop in blood pressure (& decreased brain perfusion) – confusion, loss of consciousness • Can be rapid in onset
42
Heat stroke – a medical emergency | • Treatment
``` is to sponge with tepid water (evaporative cooling) + a fan (convective cooling) • Only place ice packs over skin where large vessels are near surface (neck, under arms, groin ```
43
Fever Hyperthermia
• Set point is raised (different from other types of hyperthermia)
44
Fever Hyperthermia | • Caused by
cytokines from the immune system crossing the blood-brain barrier which increases Tset • Brain sends neural output to increase heat gain/retention to increase Tcore to new higher Tset
45
Therapeutic hypothermia
• Lowering core temp. can protect the brain from reperfusion damage post-Stroke or cardiac arrest • ↓ metabolism, reactive oxygen species, cell death, glutamate
46
Heat exchange with the environment is used to regulate body temperature via:
– Conduction – Convection – Radiation – Evaporation
47
The body produces heat from
metabolism
48
_____varies between people, throughout the day and with hormone level in females
Tcore
49
Thermoregulatory control system involves
receptors, the controller/integrator and | the effectors
50
Fever hyperthermia is initiated by
an increase in Tset
51
• Exercise hyperthermia involves a maintained increase in ?
Tcore