THINGS THAT THE REVIEW WANTED US TO MEMORIZE

Question 1

How many RNA polymerases do E. coli and humans have?

Answer 1

E. coli has just 1 Humans have 3

Question 2

UUU

Answer 2

Phenylalanine

Question 3

CCC

Answer 3

Proline

Question 4

AAA

Answer 4

Lysine

Question 5

GGG

Answer 5

Glycine

Question 6

AUG

Answer 6

Methionine (start)

Question 7

UAA

Answer 7

You are angry (stop)

Question 8

UGA

Answer 8

You go away (stop)

Question 9

UAG

Answer 9

You are gone (stop)

Question 10

What termination codon does RF1 bind too?

Answer 10

UAG UAA

Question 11

What termination codon does RF2 bind to?

Answer 11

UGA UAA

Question 12

What kind of signaling do proteins need to enter the nucleus?

Answer 12

Internal nuclear localizing sequences

Question 13

What kind of signaling do proteins need to enter peroxisomes?

Answer 13

C-terminal sequence SKF

Question 14

What kind of signaling do proteins need to enter the mitochondrial matrix?

Answer 14

N-terminal sequence rich in positive charged amino acids and serine/threonine

Question 15

What kind of proteins are signaled by ribosomes bounds to the RER?

Answer 15

Secretory proteins Lysosomal proteins Integral membrane proteins

Question 16

What does Tunicamycin do?

Answer 16

Blocks the first step in oligosaccharide synthesis

Question 17

What does bacitracin do?

Answer 17

Blocks phosphatase that recycles dolichol phosphate

Question 18

What are the current targets for gene therapy?

Answer 18

Blindness Cancer

Question 19

Define totipotent stem cells.

Answer 19

From zygote Can form whole human

Question 20

Define pluripotent stem cells.

Answer 20

From blastocyst Can form cell types from all 3 germ layers

Question 21

Define multipotent stem cells.

Answer 21

From adult Can form many closely related cell types

Question 22

What proteins are required for the ubiquitin ligase portion of Cdk/cyclin regulation?

Answer 22

SCF APC

Question 23

What proteins are required for the transcription factor portion of Cdk/cyclin regulation?

Answer 23

Jun Fos Myc E2F

Question 24

What proteins are required for the tumor suppressor portion of Cdk/cyclin regulation?

Answer 24

p53 pRb

Question 25

What proteins are required for the inhibitor protein portion of Cdk/cyclin regulation?

Answer 25

p21

Question 26

What ploidy and N does an interphase somatic cell have?

Answer 26

Diploid 2N

Question 27

What ploidy and N does a somatic cell after S phase have?

Answer 27

Diploid 4N

Question 28

What ploidy and N does a gamete prior to meiosis II have?

Answer 28

Haploid 2N

Question 29

What ploidy and N does a gamete have?

Answer 29

Haploid 1N

Question 30

What is the oocyte called in it's prolonged female diplotene stage?

Answer 30

Dictyotene

Question 31

What is ZP3?

Answer 31

A sperm receptor

Question 32

What are the MSS results for trisomy 21?

Answer 32

AFP - low uE2 - low hCG - high

Question 33

What are the MSS results for trisomy 18?

Answer 33

AFP - low uE2 - low hCG - low

Question 34

What are the MSS results for neural tube defects?

Answer 34

AFP - high uE2 - normal hCG - normal

Question 35

Define anomaly.

Answer 35

a structural defect

Question 36

Define malformation.

Answer 36

intrinsic; genetic

Question 37

Define deformation.

Answer 37

extrinsic; mechanical

Question 38

Define disruption.

Answer 38

extrinsic; teratogen exposure

Question 39

Define syndrome.

Answer 39

multiple anomalies that occur independently, but are caused by a single defect

Question 40

Define sequence.

Answer 40

when a structural or mechanical factor leads to multiple secondary effects

Question 41

What does TORCH stand for?

Answer 41

Toxoplasmosis Other (HIV, Syphilis, VZV) Rubella CMV HSV

Question 42

Answer 42

Just memorize that shit