Things to remember Flashcards
1
Q
Examples of good nucleophiles
A
I-, Br-, O-, CN-, N3-
2
Q
What reaction always proceeds with a strong base and weak nucleophile
A
E2
3
Q
Examples of bad nucleophiles
A
H2O, OH, Cl-
4
Q
What reaction proceeds with a strong base, strong nucliophile, and primary electrophile?
A
Likely SN2
More space to substitute
5
Q
What reaction proceeds with a strong base, strong nucliophile, and tertiary electrophile?
A
E2
No space for substitution
6
Q
What reaction proceeds with a strong base, strong nucliophile, and secondary electrophile?
A
Likely E2
Not much space for substitution
7
Q
Examples of strong bases
A
Anything with a metal
KOH, NAOH, NaOEt, MeOEt, KtBu
8
Q
A reaction goes toward the side with the ________ acid.
A
Weaker
high PKa, low Ka
9
Q
Strong bases
A
Fall apart in water to make
-OH ions
