Thoracic Anesthesia Part 1 Flashcards

1
Q
  • Leading cause of cancer deaths?
  • ___% of all cancer
  • ___% of all cancer deaths
  • Categorized as (2)
  • ___ new cases in US a year, 1.2 million worldwide
A
  • Lung cancer
  • 15%
  • 28%
  • Small cell carcinoma and non-small cell carcinoma
  • 200,000
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2
Q

Poor prognosis, metastatic, 3 month survival after diagnosis?
*Tumor of ____ origin (2)
(Can secrete ectopic hormones mostly ___ and ___)

A

Small cell carcinoma
*neuroendocrine origin
Lambert Easton Myasthenic syndrome, SIADH
(ACTH and ADH)

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3
Q

Linked to cigarette smoking, prognosis variable, 75-80% of all primary lung cancers?

  • ___ CONSIDERED in all patients
  • Less than 50% survive ____
A

Non-small cell carcinoma

  • surgery
  • 5 years
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4
Q
Preop = Tumor Staging (tumor size, nodal involvement, metastasis) 
0 = \_\_\_
1 = \_\_\_
2 = \_\_\_ 
3 = \_\_\_
4 = \_\_\_
A
0 = in situ
1 = localized to tissue
2 = spread to lymph nodes close by 
3 = more extensive lymph node involvement
4 = spread to other distal tissues and organs
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5
Q

Symptoms from tumor may occur in one or more category:

1) ___ = involve lung; cough, dyspnea
2) ___ = tumor growth beyond confines of the lung; pleural effusion, chest wall pain, dysphagia
3) ___ = tumor spread outside the thorax; brain, skeletal, kidney
4) ___ = Paraneoplastic syndrome: endocrine or endocrine like syndrome; cushings disease, hypercalcemia
5) ___ = weight loss, anorexia, anemia, malaise, vague cold-like syx

A

1) Bronchopulmonary
2) Extrapulmonary Intrathoracic
3) Extrathoracic Metastatic
4) Extrathoracic Non-metastatic
5) Nonspecific

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6
Q

Answer the question of “How operational or functional will the remaining lung be after resection?”

A

PFTs

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7
Q

*Major factor associated with postop pulmonary problems?

  • These 2 patients definitely need PFTs preoperatively??
  • PFTs identify patients with?
A
  • Preexisting lung dysfunction
  • Thoracic surgery candidates, patients over the age of 70
  • abnormal lung function
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8
Q

First test they do? Deep maximal inspiration followed by maximal expiration

  • Most common measurement of ?
  • Values vary with ___ and ___.
  • Normal is ___ predicted value for height and age.
  • VC decreased by (4)
A

Vital Capacity

  • lung function
  • height and age
  • > /= 80%
  • going from sitting to supine position, restrictive lung disease, loss of distensible lung tissue, max inspiration or exhalation not achieved
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9
Q
  • Reflects flow resistance in the airway?

- ___ measured in ___ and must not be interrupted by (3)

A
  • Forced vital capacity (max inspiration followed by rapid forceful expiration)
  • Exhalation
  • time
  • cough, closure of glottis, mechanical obstruction
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10
Q

Whole Lung Testing/Phase 1 Testing: 2 components

  • Detect abnormalities of ___
  • Detect abnormalities of the (3)
A
  • gas exchange
  • lung
  • chest wall
  • mechanical aspects of ventilation
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11
Q
  • ___ is reduced by the same conditions that decrease VC
  • ___ = forced expiratory volume in the first second of the FVC measurement (3 Spirograms and best FEV1 and best FVC recorded to make the ratio)
  • Normal FEV1/FVC ratio is?
A
  • FVC
  • FEV1
  • 75-80% or above
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12
Q

These 2 can help to determine postop outcome??

A

FEV1 and maximum ventilatory ventilation

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13
Q

Largest volume that can be breathed per minute by voluntary effort?
**requires high rate of ___, changes in ___ will alter this

A

Maximum ventilatory ventilation

  • *air flow
  • *airway resistance
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14
Q

MVV is reduced in ?

MVV correlates with ? (Equation?)

A

Obstructive disease
FEV1
(FEV1 X 35 = ~MVV)

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15
Q
  • FVC only normal in ___

* FEV1/FVC ratio only decreased in ___

A

*Obstructive disease
(decreased in restrictive and muscle weakness)
*Obstructive disease

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16
Q

Factors affecting ___*

-Patient effort, elastic properties of the lung, chest wall abnormalities, respiratory muscle strength

A

Maximum ventilatory ventilation

17
Q
  • Closing volume = the lung volumes at which airways begin to close or stop contributing to the expired gas
  • In the sitting position CV for healthy individuals is?
  • Elevated in ___!!! (Reflects loss of ___ or ___)
A
  • 15-20% of VC
  • Smokers!!!
  • loss of elastic recoil and/or small airway pathology
18
Q
  • ___ = ability of the lung to perform gas exchange (inhale CO and tested)
  • ___ of postop predicted value is high risk
A
  • Diffusing Capacity

- less than 40 percent

19
Q
  • ___ = Maximum oxygen consumption during exercise testing
  • Decrease of ___ during exercise testing is considered high risk
  • Preop ___ = high risk
A
  • VO2max
  • 4%
  • Preop VO2max of less than 15 ml/kg/min
20
Q

2 additional tests predictive of postop outcome?

A

Diffusing capacity and VO2max

21
Q

Increased operative risk if (4)

A

1) ABG shows hypercapnia on room air
2) FEV1 less than 50% of FVC
3) FEV1 less than 2 liters
4) RV/TLC >50%

22
Q

Phase 3 Testing: Can’t tolerate procedure if….

  • PAP = ___
  • PaCO2 = ___
  • PaO2 = ___
A
  • PAP >40 mmHg
  • PaCO2 >60 mmHg
  • PaO2 less than 45
23
Q
  • Second most common cause of periop M&M?

- Biggest issue with COPD patients is ? (They can’t tolerate increases in their ___, on oxygen at home)

A
  • Cardiac complications
  • right sided heart failure (RV hypertrophy and dilation)
  • afterload
24
Q
Prevention of arrhythmias:
Drug Prophylaxis (4)
A

Amiodarone
Diltiazem (most common)
Digoxin
Beta blockers

25
Q

Asthma and Anesthesia: Bronchoactive drugs (5)

A
Anticholinergics
Beta agonists
Corticosteroids 
Cromolyn
Methylxanthines
26
Q

Signs and symptoms of this include = dyspnea, syncope, PA mean pressure greater than 20, prominent “A” wave on CVP, can be overt right heart failure?

-On these patients avoid???

A

Cor Pulmonale
(right ventricular enlargement secondary to pulm HTN)

-hypoxemia, hypercarbia, nitrous oxide

27
Q

Treat cor Pulmonale by decreasing RV workload with (6)

A
  • Digoxin
  • Diuretics
  • Antibiotics
  • Vasodilators
  • Anticoagulants
  • Supplemental oxygen
28
Q
  • Pneumonia most often?

- URI most often?

A
  • Bacterial

- Viral

29
Q

Sarcoidosis: systemic granulomatous disorder, involves liver, spleen, heart, thoracic lymph nodes (laryngeal sarcoid may interfere with passage of ETT). Usually treated with corticosteroids.

  • May develop? (4) (1 = rare)
  • Increased ___
A
  • cor Pulmonale, heart block, dysrhythmias, restrictive cardiomyopathy (hypercalcemia=rare)
  • ACE activity
30
Q

Hallmark symptoms of Pneumothorax and Hemothorax????

-Chest tube if pneumo is >20%

A
Hypoxemia
Tachycardia
Hypotension
Increased CVP
(Also will have diminished breathe sounds where pneumo is)
31
Q
  • With resp acidosis see ___!!! (Anxiety, confusion, CO2 narcosis, cerebral vasodilation and increased CVP, HTN, tachy, increase cate activity)
  • With resp alkalosis will see ___!!! (Light headed, coma, confusion, seizures, tetany, vent dysrhythmias, hypotension, decreased CO)
A
  • Hyperkalemia

- Hypokalemia

32
Q
  • See ventricular dysrhythmias, Hypokalemia, seizures, tetany, hypotension, decreased CO, cerebral vasoconstriction?
  • See confusion and lethargy, twitching, nm irritability?
  • See fatigue, somnolence, confusion, impaired contractility, decreased SVR, anaerobic production of lactic acid, impaired oxy-Hgb binging?
  • See anxiety, confusion, CO2 narcosis, cerebral vasodilation, HTN, tachy, Hyperkalemia?
A
  • Resp alkalosis
  • Metabolic alkalosis
  • Metabolic acidosis
  • Resp acidosis
33
Q

Base/deficit equation?
(Uses level of 24)
-Typically give ___ and recheck in ___.

A

Base deficit x weight (kg) x 0.3 = ___ meq NaHCO3

-one half dose and recheck in 5 minutes