Thromboembolitic Disease Flashcards
(21 cards)
According to Virchows triad which three things contribute to thromboembolitic disease?
Stasis
Increased coagubility
Endothelial damage
What are the symptoms of DVT?
OFTEN NONE
Pain
Swelling
Tenderness
Fever
What are the investigations for a DVT?
Doppler
D Dimer
What is the management of a DVT?
LMW heparin (clexane) until confirmed,
Then warfarin for 3/12 if the cause is known
What could be used to measure the likelihood of there being a DVT?
Wells score
eg, malignancy
Pitting oedema in symptomatic leg
Previous DVT
What does PE lead to?
Pulmonary infarction
What is this?
Wedge sign (PE)
What are the symptoms of PE?
They can range from none to sudden death
SOB
Tachypnoea
Pleuritic pain
Hyper/hypotension
Haemoptysis
Fever
What are the cardinal symptoms of PE
Tachynpnoea
Dysopnea
Pleuritic Pain
What are the classifications of PE?
Massive - Acute -Low CO, collapse, hypoxaemia, hypotension
Subacute - progressive occlusion and hypertension, hypoxaemia
Minor - SOB, pleuritic pain, haemoptysis and fever
Chronic - recurrent causing pulmonary hypertension and SOB
What are some risk factors for PE?
Surgery
Malignancy
Thrombophilia
Fractures
COPD
What may an CXR show?
Wedge
What may an ecg show?
PEA
S1 Q3 T3
What would a d dimer show?
Elevated
What would a V/Q show?
Mismatch
What is a principle of management>
Risk of anticoag therapy V burden of disease.
Eg, alcoholics, COPD and Ca have a high burden but there is a risk of CVAs, peptic ulcer bleeds
What is the acute management?
O2
Fluids
Analgesia
Clexane and Tpa
When would you do a thrombophilia screen?
Repeated
Young
FH
PE despite anti coag
Recurrent miscarriages
When would you not do a thrombophilia screen?
Pregnant
On anticoag therapy
Liver disease
What are some thromobophilia diseases that could cause PEs
Inherited - Protein C or S deficiency
Factor V leiden
Acquired - LUPUS
Anti phospholipid syndrome
Increased factor 8
What is a non drug method for prophylaxis?
IVC filter
