Thyroid Lecture Flashcards

(74 cards)

1
Q

Thyroid gland location

A

Small saddle-shaped gland that wraps around the anterior portion of the trachea

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2
Q

Thyroid hormone regulates:

A
Metabolic rate
heart function
digestive function
muscle control
brain development
bone maintenance
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3
Q

Used to produce hormones:

A

iodine

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4
Q

Serum TA Normal Value

A

Negative to 1:20

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5
Q

Serum TSH (sensitive assay) Normal value

A

0.35-5.5mU/mL

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6
Q

Serum T4 Normal Values

A

4.5-11.5 mcg/dL

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7
Q

Serum T3 Normal Values

A

80-200 ng/dL

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8
Q

T3 uptake Normal Values

A

25-35 relative percentage

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9
Q

Thyroid Suppression Findings in Hyperthyroidism

A

^ RAI uptake and T4 levels

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10
Q

Serum TA Test Findings in Hyperthyroidism

A

Increased

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11
Q

Serum TSH (sensitive assay) Findings in Hyperthyroidism

A

Decreased in primary hyperthyroidism

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12
Q

Serum T4 Findings in Hyperthyroidism

A

Increased

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13
Q

Serum T3 Findings in Hyperthyroidism

A

Increased

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14
Q

T3 Uptake findings in hyperthyroidism

A

Increased

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15
Q

Sympathetic Nervous System

A

fight or flight

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16
Q

Hyperthyroidism ________metabolic rate.

A

Increases

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17
Q

Hyperthyroidism is caused by an excessive delivery of_____.

A

thyroid hormone

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18
Q

Hyperthyroid_______SNS.

A

Increases

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19
Q

Hyperthyroidism Risk Factors

A
Women 10x
Genetic Factors
Family History of Graves
^ Iodine intake
20-40 age
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20
Q

Hyperthyroidism S/S

A
  • ^ appetite w/ weight loss
  • hypermotile bowels
  • heat intolerance
  • insomnia
  • palpitations
  • ^ sweating
  • hair changes
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21
Q

Most common cause of hyperthyroidism

A

Graves Disease

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22
Q

Graves disease is an ______.

A

autoimmune disorder

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23
Q

Autoimmune disorder:

A

antibody in serum binds to TSH receptors in thyroid follicles causing hyperfunction

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24
Q

Goiter:

A

Enlarged thyroid gland in the neck

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25
Graves disease S/S:
``` Exophthalmos eye pain blurred vision diplopia lacrimation photophobia ```
26
Graves Disease ^ risk of:
corneal dryness irritation infection ulceration
27
Another most common hyperthyroidism
Toxic Multinodular Goiter
28
TMG develops:
slowly, usually in women in 60s and 70s
29
TMG:
small, independently functioning nodules
30
TMG does not have signs of:
opthalmopathy, dermopathy
31
Subacute granulomatous thyroiditis
viral infection
32
acute thyroiditis
bacterial or fungal infection
33
What is thyroiditis?
acute disorder that may become chronic, resulting in a hypothyroid state as the repeated infections destroy the thyroid gland tissue
34
T3 and T4 levels in thyroiditis:
initially elevated but over time become depressed
35
Thyroiditis delivery:
weeks or months
36
Bacterial thyroiditis treatment:
antibiotics or surgical drainage
37
Thyroiditis Meds:
NSAIDS progressing to corticosteroids if needed
38
Thyroiditis meds r/t cardiovascular S/S:
Propanolol or Atenolol
39
Thyroid Storm:
Thyrotoxic Crisis | •extreme state of hyperthyroidism
40
Thyroid Storm is considered:
a life threatening emergency, death rare when treatment started earlier
41
Thyroid storm manifestations:
Sever tachy, hf, shock, hyperthermia (105.3), restlessness, agitation, seizures, abd pain, N/V/D, delirium, coma
42
Thyroid storm treatment:
decrease circulating thyroid hormone levels with drug therapy
43
Thyroid storm supportive therapy:
managing resp distress fever reduction fluids elimination/management of stressors
44
Excess TSH Stimulateion is a ______ form of hyperthyroidism.
Secondary and it is rare
45
Excess TSH Stimulation caused by:
overproduction of TSH by the pituitary gland and usually stimulates the thyroid gland to produce excess of thyroid hormone
46
Antithyroid drugs:
Pylthioruacil | Methimazole
47
Hyperthyroidism drugs:
iodine SSKI | Beta Blockers
48
Thyroid Treatments
antithyroid meds RAI therapy Subtotal thyroidectomy
49
Radioactive Iodine Therapy:
damages or destroys thyroid tissue
50
RAI Outpatient:
given orally
51
RAI Treatment S/E
dryness, irritation of mouth and throat during treatment
52
80% of RAI cases experience
hypothyroidism in post-treatment
53
Two types of thyroidectomies
Subtotal | Total
54
Subtotal Thyroidectomy:
leaves about 10% of thyroid gland and the remainder will produce adequate TH
55
Total Thyroidectomy:
Total removal of gland, pt will have lifelong hormone replacement.
56
Hyperthyroidism Surgery Post-Op complications
* Hypothyroidism * Hemorrhage * Damage to Parathyroid gland - hypocalcemia * Injury to laryngeal nerve - vocal cord analysis * Infection * Resp Distress
57
Post-Op Protocols
Semi fowlers, suppor head and neck avoid flexion watch for tracheal compression
58
Hyperthyroidism Evaluation:
``` cardiac stabilize regains visual acuity appropriate calories feelings body image med requirements ```
59
Hypothyroidism TH production:
decreases
60
Thyroid gland _______ in attempt to produce more hormone.
Enlarges
61
Hypothyroid state leads to:
myxedema
62
Hypothyroid Primary Etiology:
Defects in gland (congenital), loss of thyroid tissue, antithyroid meds, thyroiditis, endemic iodine deficiency
63
Hypothyroid Secondary Etiology:
Pituitary TSH deficiency or peripheral resistance to TH, meds can cause it, common in women 30-60
64
Hypothyroidism: Serum TA Normal Values:
None to 1:20
65
Hypothyroidism: Serum TA Findings:
Normal
66
Hypothyroidism: Serum TSH Normal Values
0.35-5.5 mU.mL
67
Hypothyroidism: Serum TSH Findings
Increased in primary hypothyroidism
68
Hypothyroidism: Serum T4 Normal Values
4.5-11.5 mcg/dL
69
Hypothyroidism: Serum T4 Findings
Decreased
70
Hypothyroidism: Serum T3 Normal Values
80-200 ng/dL
71
Hypothyroidism: Serum T3 Findings
Decreased
72
Hypothyroidism: Serum T3 uptake Normal Values
25-35 relative percentage
73
Hypothyroidism: T3 uptake Findings
Decreased
74
Hypothyroidism: Thyroid Depression Findings:
No change in RAI uptake of T4 levels