Tig ol bitties (ERF)

Question 1

Lactiferous ducts has what kind of epithelium

Answer 1

columnar epithelium

-note terminal ducts have cuboidal epithellium

Question 2

extralobular or intralobular terminal duct. which one will become secretory if women begins to lactate

Answer 2

intralobular terminal ducts

-he also said acini have become true secretory units for lactation

Question 3

the ducts and lobules have what on their outer layer that makes the milk come down during breast feeding

Answer 3

myoepithelium

Question 4

tx with methyldopa therapy can cause what clinical thing with the woman

Answer 4

galactorrhea-amenorrhea

Question 5

What hormone makes the big ducts & stroma to grow? Estrogen, Progesterone, Prolactin, Oxytocin

Answer 5

estrogen

Question 6

What hormone makes the little ducts and acinar units grow? Estrogen, Progesterone, Prolactin, Oxytocin

Answer 6

Progesterone

Question 7

What hormone develops the acini as secretory units? Estrogen, Progesterone, Prolactin, Oxytocin

Answer 7

Prolactin

Question 8

what hormone makes the myoepithelium contract for lactation? Estrogen, Progesterone, Prolactin, Oxytocin

Answer 8

Oxytocin

Question 9

In older woman’s breast. what remains and what is gone? ducts and lobules

Answer 9

Ducts remain, lobules gone

Question 10

what tumor can cause premature breast development

Answer 10

estrogen-producing ovarian tumor

Question 11

what bug is usually the cause for breast abscess/acute mastitis

Answer 11

staph

Question 12

“idiopathic” fat necrosis of the breast is usually caused by what

Answer 12

trauma

-will see fat-laden macrophages

Question 13

what can produce dilated ducts filled with a curious putty-like lipid-and-macrophage rich material

Answer 13

Duct ectasia

Question 14

Lymphocytic mastopathy is an autoimmune dz that has the lymphocytes eating up TDLU’s. what other autoimmune dz’s runs w/ this

Answer 14

hashimoto’s and Type I diabetes

Question 15

which gigantomastia has antinuclear antibodies? gestational or inflammatory gigantomastia

Answer 15

inflammatory gigantomastia

Question 16

If TDLU’s are replaced w/ granulomas, what do we know for sure about our patient

Answer 16

she has been pregnant. The cause is presumably immune

Question 17

what is Mondor’s?

Answer 17

a thrombosed vein

Question 18

simple cyst of the breast. see a blue dome on biopsy. is it harmful

Answer 18

nope harmless

Question 19

what kind of adenosis do we feature glands w/ tall cells

Answer 19

blunt duct adenosis

-no extra malignant potential

Question 20

what adenosis do we see the acini proliferate but the basic architecture of the breast is intact.. You will triple the risk of eventual invasive cancer

Answer 20

sclerosing adenosis

Question 21

what does CK5/5 show

Answer 21

myoepithelium

Question 22

what common benign breast tumor do we see stroma hyperplasia

Answer 22

fibroadenoma

Question 23

“a fibroadenoma w/ a very cellular stroma”

Answer 23

phyllodes tumor

-could be a sarcoma

Question 24

bloody discharge and its benign. A galactogram is a great way to spot these tumors

Answer 24

intraductal papillomas

Question 25

what has a bad prognostic sign, which is due to impingement on lymphatic vessels

Answer 25

Peau d'orange

Question 26

what resembles blackheads on gross exam, and the necrotic cores can be squeezed out. Often the necrotic cores calcify.

Answer 26

comedocarcinoma

Question 27

Lady comes in thinking she got poison ivy of the nipple?? what cancer can it be

Answer 27

Paget's of the breast, underlying cancer invading the epidermis on the nipple

Question 28

what cancer cells tend have clear cytoplasm

Answer 28

paget cells

Question 29

what carcinoma tends to have the lobules distended and lobular lesions tend to feature non-cohesiveness? ductal carcinoma in situ or lobular carcinoma in situ

Answer 29

LCIS - note LCIS is cadherin negative - note DCIS is cadherin positive

Question 30

what do we commonly see in invasive ductal carcinoma

Answer 30

indian files

Question 31

Big polygonal cells, lots of lymphocytes? DCIS, LCIS, meduallary carcinoma

Answer 31

medullary carcinoma

Question 32

Invasive LCIS or DCIS. which one do we see signet ring cells

Answer 32

invasive LCIS

Question 33

what does the patient have if they have active-looking ducts often w/ loose surrounding stroma, but no glands

Answer 33

gynecomastia

Question 34

what is the grading system for non-invasive breast cancer via the college of american pathologist

Answer 34

1) nuclei are uniform, not bigger than 2.o RBC diameter's 2) In-between 3) Nuclei are generally bigger than 2.5 RBC diameters and the chromatin is coarse, nucleoli are multiple and/or prominent, just looks ugly

Question 35

Nottingham-bloom-richardson grading system for invasive breast cancer

Answer 35

Look at powerpoint

Question 36

when do we think of breast cancer in fat

Answer 36

inflammatory breast cancer

Question 37

Patients with breast cancer often present with what cheif complaint

Answer 37

BONE PAIN, deals with osteoblast