Tissue Renewal and Repair

Question 1

What is Healing?

Answer 1

Tissue Response to:
Wound
Inflammatory Processes in Internal Organs
Cell Necrosis in organs incapable of regeneration

Question 2

What are the 2 Processes of healing?

Answer 2

Regeneration

Replacement by Connective Tissue

Question 3

What is Regeneration?

Answer 3

Proliferation of surviving cells to replace lost tissue

Migration of surviving cells into vacant space

Question 4

What are the groups of body tissues according to their proliferative activity?

Answer 4

Labile Tissues
Stable/ Quiescent Tissues
Permanent (nondividing) Tissues

Question 5

What are Labile tissues?

Answer 5

They divide actively throughout life to replace lost cells

They regenerate following injury

Question 6

What are examples of Labile Tissues?

Answer 6

Cells of the epidermis and gastrointestinal mucosa,
Lining of GUT,
Hematopoietic Cells of bone marrow

Question 7

What are Stable or Quiescent Tissues?

Answer 7

Undergo Few divisions but capable of division when activated

Regenerate following injury

Question 8

What are examples of Stable or Quiescent tissues?

Answer 8

Hepatocytes
Renal Tubular Cells
Parenchymal Cells of many glands
Mesenchymal Cells

Question 9

What are examples of mesenchymal cells?

Answer 9

Smooth muscle
Cartilage
Connective Tissue
Endothelium
Osteoblasts

Question 10

What are Permanent Tissues?

Answer 10

Incapable of division and regeneration

Replaced by Scar tissue/ fibrosis/ gliosi in the CNS

Question 11

What are examples of Permanent/ non-dividing tissues?

Answer 11

Majority of neurons, myocardial cells