Tissue Repair Flashcards
(38 cards)
example of Intact physical barriers
the skin and mucous membranes, cilia, and the strong acid produced by stomach glands
these intact physical barriers are exerted at what level
local tissue level
When tissue injury does occur,
it stimulates the body’s what
inflammatory and immune response
when does the healing process begin
almost immediately
Inflammation
is a generalized (nonspecific) body response that attempts to prevent further injury
The immune response, in contrast,
is
extremely specific and mounts a vigorous attack
against recognized invaders, including bacteria,
viruses, and toxins.
Tissue repair, or wound healing, occurs in
two major ways:
by regeneration and by fibrosis
Regeneration
is the replacement of destroyed tissue by the same kind of cells
fibrosis
involves repair by dense (fibrous) connective tissue, that is, by the formation of scar tissue.
Which occurs depends on
(1) the type of tissue damaged
and (2) the severity of the injury
Generally speaking, clean cuts (incisions) heal much more
successfully than ragged tears of the tissue
Tissue injury sets a series of events into motion:
inflammation sets the stage
granulation tissue forms
Regeneration and fibrosis effect permanent repair
injure tissue cells and other release what in the first stage
. Injured tissue cells and others release inflammatory chemicals
the inflammatory chemicals do what
make the capillaries very permeable
the capillaries being very permeable allow for what
This allows fluid rich in clotting proteins and other
substances to seep into the injured area from
the bloodstream
Then leaked clotting proteins
construct a what
clot
what does a clot do
stops the loss of blood, holds the edges of the wound together, and walls off the injured area, preventing bacteria or other harmful substances from spreading to
surrounding tissues.
Where the clot is exposed
to air
it quickly dries and hardens, forming a
scab.
what is Granulation tissue
is a delicate pink tissue composed largely of new capillaries that grow into the damaged area from undamaged blood vessels nearby.
describe these capillaries in granulation tissue
These capillaries are fragile and
bleed freely, as when a scab is picked away
from a skin wound.
Granulation tissue also
contains what
phagocytes that eventually dispose
of the blood clot and connective tissue cells
(fibroblasts) that produce the building blocks
of collagen fibers (scar tissue) to permanently
bridge the gap
As the surface epithelium begins
to regenerate, it makes its way across the
granulation tissue just beneath the scab
when the scab detaches what’s the final result
fully regenerated surface epithelium that covers an underlying area of fibrosis (the scar).
The scar is either invisible or visible as a thin
white line, depending on the severity of the
wound
the scar is a
white line depending on the severity of the
wound. it can visible or invisible
