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BME 510 > Tissues > Flashcards

Tissues Flashcards

1
Q

How are tissues held together?

A

By secreted ECM molecules

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2
Q

How are cells kept in place?

A

By cell-cell adhesion

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3
Q

What are the four basic body tissues?

A

Nervous, muscle, epithelial, and connective

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4
Q

What does neural tissue do?

A

Conduct nerve impulses in brain, spinal cord, nerves

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5
Q

What does muscle tissue do?

A

Contract to move skeleton, pump blood, propel food

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6
Q

What does epithelial tissue do?

A

Cellular sheets to line organs (barrier)

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7
Q

What does connective tissue do?

A

Secrete ECM to support body and connect parts (bone, blood, etc.)

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8
Q

What is the form of muscle tissue?

A

Elongated

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9
Q

What do fibroblasts do?

A

Generate fibers

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10
Q

What do macrophages do?

A

Consume dead cells

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11
Q

How are epithelial cells and nervous tissue similar?

A

They are both elongated and participate in conduction

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12
Q

What is an example of an organ with all types of tissue?

A

Intestine

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13
Q

What tissues does the intestine have?

A
  1. Epithelial cells for boundary
  2. Connective tissue (fibroblasts) to join layers through ECM
  3. Smooth muscle cells for perastalsis
  4. Neural tissue
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14
Q

How dense is ECM?

A

Cells are sparse

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15
Q

What is the majority of ECM and why?

A

Collagen, because it bears most of mechanical stress

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16
Q

What is the structure of ECM?

A

Lots of fluid, and few cells

17
Q

How can ECM be different?

A

It is hard/rigid in bone, firm in cartilage, fibrous in facia, flexible/tough/strong in skin, and fluid in blood

18
Q

What is ground substance?

A

The fluid gel in ECM that shapes amorphous surrounding tissues

19
Q

How do the properties of the ECM arise?

A

From hydrophilic proteoglycans and glycoproteins interacting with electrolytes

20
Q

What provides elasticity in the ECM?

A

Elastin molecules

21
Q

What is important to generate elasticity for biopolymers?

A

Crosslinking

22
Q

What happens in rheumatoid arthritis?

A

Collagen is degraded

23
Q

What happens in athereosclerosis?

A

Too much collagen is secreted, so it accumulates with fats in walls of vessels

24
Q

What are reticular fibers?

A

Mesh-like internal structure that has collagen fibrils to support basement membrane of epithelia and vascular endothelial

25
Q

What is single epithelial?

A

Single layer

BME 510 (2 decks)

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