TLRs Flashcards
1
Q
how many TLRs (Toll-like receptors) does the human body have?
A
2
Q
what are TLRs?
A
- TLRs = receptors found in the membranes of leukocytes
- detect presence of foreign pathogens
- activate immune cells
3
Q
what are TLRs a type of?
A
Pattern recognition receptors (PRRs)
4
Q
which cells do you find TLRs on?
A
- sentinel cells (cells in body’s first line of defence)
examples of sentinel cells:
- macrophages
- dendritic cells
- natural killer cells
- mast cells
