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Pharmacy Revision > To Crush or Not to crush > Flashcards

To Crush or Not to crush Flashcards

For patients who can't swallow, can their medication be altered.. (117 cards)

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1
Q

Acetazolamide MR

A

DO NOT CRUSH

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2
Q

Acetazolamide

A

Non MR?

Yeah go ahead and disperse this in water

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3
Q

Alendronate

A

LAST RESORT - crush and administer via NG/PEG tube if ESSENTIAL patient continues treatment

REMEMBER must be given on an EMPTY STOMACH - which means after 4 hour fast, and 30 minutes before any other medication or food

does the patient really need to be on this?
Maybe consider changing to strontium if for post menopausal osteoporosis

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4
Q

Alfuzosin MR

A

DO NOT CRUSH

change to non-MR

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5
Q

Alfuzosin

A

Non MR?

Yeah go ahead and disperse this in water

if changed from MR then 2.5mg TDS which can be crushed and dispersed in water

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6
Q

Allopurinol

A

Yeah go ahead, crush, mix with water and administer

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7
Q

Alverine

A

Yeah go ahead - Capsule can be opened and dispersed in water

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8
Q

Aminophylline

A

NO
Change to equivalent dose of theophylline liquid - 60mg/5ml
Stop feed for 1 hour before an 2 hours after and monitor plasma levels of the drug

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9
Q

Amiodarone

A

Yeah go ahead and disperse this in water

Will not taste nice so can be mixed with fruit juice if NOT for enteral feeding tube

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10
Q

Amlodipine

A

Yeah go ahead and disperse this in water

NB to administer immediately as light sensitive

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11
Q

Anastrazole

A

Yeah go ahead, crush, mix with water and administer

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12
Q

Atorvastatin

A

Yeah go ahead, crush, mix with water and administer
(not very soluble, therefore if given via enteral feeding tube make sure tube is flushed well after administration to avoid blockage)

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13
Q

Azathioprine

A

Yeah go ahead, crush, mix with water and administer

CYTOTOXIC - so remember to wear gloves, and dispose of container and clean up spillages as per cytotoxic guidelines

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14
Q

Bendroflumethiazide

A

Yeah go ahead and disperse this in water

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15
Q

Betahistine

A

Yeah go ahead and disperse this in water

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16
Q

Bezafibrate

A

Non-MR?

Yeah go ahead, crush, mix with water and administer

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17
Q

Bezafibrate MR

A

DO NOT CRUSH

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18
Q

Bisoprolol

A

Yeah go ahead, crush, mix with water and administer
(not very soluble, therefore if given via enteral feeding tube make sure tube is flushed well after administration to avoid blockage)

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19
Q

Buspirone

A

Yeah go ahead, crush, mix with water and administer

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20
Q

Cabergoline

A

Yeah go ahead, crush, mix with water and administer

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21
Q

Calcium/Vitamin D3

A

If unable to chew CHANGE to Calfovit D3 sachets at equivalent dose

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22
Q

Candesartan

A

Yeah go ahead, crush, mix with water and administer

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23
Q

Captopril

A

Yeah go ahead disperse in water

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24
Q

Carbimazole

A

Yeah go ahead, crush, mix with water and administer

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25
Carvedilol
Yeah go ahead, crush, mix with water and administer (will form a suspension)
26
Celecoxib
DO NOT OPEN CAPSULES - will affect the stability of the drug
27
Chlordiazepoxide
Yeah go ahead open the capsule, mix with water and administer
28
Cinnarizine
Yeah go ahead, mix with water and administer
29
Ciprofloxacin
Yeah go ahead, crush, mix with water and administer | suspension is too think for enteral feeding tubes
30
Citalopram
``` DROPS AVAILABLE NB 8mg (4 drops) = 10 mg tablets ``` Mix with water before administering
31
Clindamycin
Yeah go ahead, open capsule, mix with water and administer
32
Clobazam
Yeah go ahead, crush, mix with water and administer | does not taste nice
33
Clonazepam
Yeah go ahead, crush, mix with at least 30 mls of water and administer
34
Clopidogrl
Yeah go ahead disperse in water and administer (will take about 5 minutes to completely disperse)
35
Co-amilozide
Yeah go ahead, crush, mix with water and administer
36
Co-beneldopa
DISPERSIBLE TABLETS AVIALABLE
37
Co-careldopa
Yeah go ahead, crush, mix with water and administer consider changing to co-beneldopa dispersible tablets
38
Co-phenotrope
Yeah go ahead, crush, mix with water and administer
39
Cyclizine
Yeah go ahead, crush, mix with water and administer | Bitter taste
40
Cyproterone
Yeah go ahead, crush, mix with water and administer
41
Dantrolene Capsules
Yeah go ahead, open the capsule, mix with ORANGE JUICE and administer - maintain the acidity
42
Demeclocyline
DO NOT OPEN CAPSULES contents of the capsule do not disperse in water and may cause severe irritation to the mucosa
43
Digoxin
LIQUID FORMULATION AVAILABLE NB bioavailablity different 62.5mcg tablet = 50 mcg liquid
44
Diltiazrm
OD MR and BD MR preparations should NOT BE CRUSHED | The 60mg MR TDS formulation is not slow released and CAN BE CRUSHED
45
Dipyridamole
SYRUP AVAILABLE But yeah go ahead, open the capsule, mix with water and administer buy mouth NOT SUITABLE FOR ENTERAL FEED DO NOT CRUSH TABLETS
46
Donepezil
Yeah go ahead, crush, mix with water and administer
47
Doxazosin
Yeah go ahead, mix with (STERILE- not tap) water and administer
48
Entacapone
Yeah go ahead, crush, mix with water and administer (not very soluble, therefore if given via enteral feeding tube make sure tube is flushed well after administration to avoid blockage - may stain orange)
49
Eprosartan
Yeah go ahead, crush, mix with water and administer
50
Escitalopram
Consider switching to citalopram which is available as a liquid
51
Esomeprazole
Yeah you can..but it will leave pellets which SHOULD NOT be crushed. consider a different PPI?
52
Ethambutol
Yeah go ahead, crush, mix with water and administer
53
Exetimibe
NOPE | does not mix well with water
54
Felodipine
MR - DO NOT CRUSH Consider changing to amlodipine - which can be crushed
55
Ferrous Sulphate
LIQUID PREP AVAILABLE | Change to equivalent dose
56
Finasteride
Place the tablet IN THE BARREL of an oral or bladder-tipped syringe, draw up water and allow to dissolve. NB WOMEN OF CHILD BEARING AGE should NOT handle crushed, broken or dissolved tablets
57
Fludrocortisone
Yeah go ahead, crush, mix with water and administer
58
Forceval
snip off the end of the capsule and withdrawal contents using a syringe Does not mix well with water - so be careful if using an enteral feeding tube Unpleasant taste.
59
Gabapentin
Yeah go ahead, open the capsule, mix with water and administer immediately
60
Glibenclamide
Yeah go ahead, crush, mix with water and administer
61
Gliclazide
Non-MR? | Yeah go ahead, crush, mix with ORANGE JUICE and administer
62
Glimepiride
DO NOT CRUSH - my affect bioavailability
63
Glipizide
Yeah go ahead, crush, mix with water and administer
64
Hydrocortisone
Yeah go ahead, crush, mix with water and administer
65
hydroxyurea
CYTOTOXIC - Handle with care but Yeah, capsules can be opened, mixed with water and administer
66
Hyoscine Butylbromide
DO NOT CRUSH | Administer injection orally if necessary
67
Hyoscine Hydrobromide
PATCH AVAILABLE
68
Irbesartan
Yeah go ahead, crush, mix with water and administer
69
Isosorbide Dinitrate
Non-MR? | Yeah go ahead, crush, mix with water and administer
70
Labetalol
Injection can be used orally mix with orange juice if necessary to disguise bitter taste
71
Lansoprazole
SUSPENSION SACHETS AVAILABLE - not suitable for enteral feeding tube (liquid sticks to the tube) FAST-TABS available which can either be swallowed whole, dissolved in the mouth, or dissolved in water if necessary
72
Levomepromiazine
Yeah go ahead, mix with water and administer or use the injection orally
73
Levothyroxine
Yeah go ahead, crush, mix with water and administer
74
Lisinopril
Yeah go ahead, mix with water and administer
75
Lorazepam
Yeah go ahead, crush, mix with water and administer
76
Lormetazepam
Yeah go ahead, mix with water and administer or change to temazepam
77
Losartan
Yeah go ahead, crush, mix with water and administer
78
Menadiol
Yeah go ahead, crush, mix with water and administer
79
Mesalazine
GRANULES AVAILABLE - these are MR and will contain small particles - may not be suitable to go down enteral feeding tube
80
Metformin
Yeah go ahead, crush, mix with water and administer | Metformin SATCHETS are available in 500mg and 1 G
81
Methylprednisolone
Yeah go ahead, mix with water and administer
82
Metolazone
Yeah go ahead, crush, mix with water and administer
83
Metoprolol
Yeah go ahead, crush, mix with water and administer or use injection orally
84
Mirtazepine
ORODISPERSIBLE TABLETS will dissolve in water
85
Monteleukast
CHEWABLE TABLETS will disperse in water
86
Moxonidine
Yeah go ahead, crush, mix with water and administer
87
Morphine Sulphate MR Caps (zomorph)
Yeah go ahead, open capsule (BUT DO NOT CRUSH), mix with water and administer or change to Oramorph
88
Naftidrofuryl
Yeah go ahead, open capsule, mix with water and administer NOTE: risk of oesophageal stricture if used orally in patients with swallowing difficulties - to avoid this the patients should drink 4-5 glasses of water after each dose
89
Nicardipine
Non-Mr capsules? Yeah go ahead, open capsules, mix with ORANGE JUICE and administer
90
Nicorandil
Yeah go ahead, crush, mix with water and administer NB: tablets are hygroscopic and they should be used with care in enteral feeding tube as may cause blockage
91
Nifedipine
MR? - DO NOT CRUSH as non-MR are not recommended for treatment of angina or long term control of hypertension, it is better to change to an alternative CCB such as amlodipine which can be dispersed in water
92
Nimodipine
Yeah go ahead, crush, mix with water and administer immediately
93
Olanzepine
Use VELOTABS and disperse in water
94
Pantoprazole
DO NOT CRUSH | consider changing to alternative
95
Phenelzine
Yeah go ahead, crush, mix with water and administer immediately (unstable in water)
96
Phenytoin
SYRUP AVAILABLE 90mg Syrup = 100mg Capsule for enteral feed - to avoid adsorption to the tubing, mix with equal volume of water and flush with 30ml of water before and after administering phenytoin
97
Pramipexole
Yeah go ahead, crush, mix with water and administer
98
Pravastatin
Yeah go ahead, crush, mix with water and administer
99
Prazosin
Yeah go ahead, crush, mix with water and administer
100
Quetiapine
Crush and dissolve in WARM water | For oral use can mix crushed tablet with yogurt to disguise bitter taste
101
Ramipril
Yeah go ahead, crush, mix with water and administer | Capsules can be opened and dispersed in water
102
Riluzole
Yeah go ahead, crush, mix with water and administer | Crushed tablets can also be mixed with soft food (such as yogurt) to aid swallowing
103
Risedronate
LAST RESORT - crush and administer via NG/PEG tube if ESSENTIAL patient continues treatment REMEMBER must be given on an EMPTY STOMACH - which means after 4 hour fast, and 30 minutes before any other medication or food
104
Rosiglitazone
Yeah go ahead, crush, mix with water and administer
105
Sertraline
Yeah go ahead, mix with water and administer | can be crushed and mixed with food
106
Simvastatin
Yeah go ahead, crush, mix with water and administer
107
Sotalol
Yeah go ahead, crush, mix with water and administer
108
Tamsulosin
MR SHOULD NOT BE CRUSHED change to an alternative alpha-blocker
109
Theophylline
LIQUID AVAILABLE | Stop feed for 1 hour before an 2 hours after and monitor plasma levels of the drug
110
Tolbutamide
Yeah go ahead, crush, mix with water and administer
111
Tolterodine
Yeah go ahead, mix with water and administer
112
Tranexamic Acid
Yeah go ahead, crush, mix with water and administer - Can take upto 5 minutes to dissolve Injection can be used orally
113
Valsartan
Capsules can be opened and dispersed in water | Use immediately!
114
Vacomycin
Injection can be used orally
115
Venlafaxine
Non-MR? | Yeah go ahead, crush, mix with water and administer
116
Warfain
Yeah go ahead, crush, mix with water and administer
117
Zopiclone
DO NOT CRUSH | consider changing to temazepam liquid

Pharmacy Revision (11 decks)

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