TOP 200 DRUGS Flashcards Preview

Pharm I: Exam 3 > TOP 200 DRUGS > Flashcards

Flashcards in TOP 200 DRUGS Deck (41):
1

Diclofenac

NSAID→Acetic acids

RA, OA, Ankylosing spondylitis

2

Trazadone

Newer Antidepressants

TX depression and sedative (migraine prevention)

3

Ropinirole

Parkinson's

TX Parkinson disease (monotherapy for early, adjunct tx for advanced)

4

Aspirin

NSAID→Salicylate

Prophylactically:  DEC incidence of CVD (MI, unstable angina)

LOW DOSE: Antipyretic, Analgesic 

HIGH DOSE: Anti-inflammatory 

Chronic usage: CA prevention

5

Ferrous sulfate

TX iron deficiency anemia

6

Lamotrigine

Epilepsy→Prolonged inactivation of VG Na+ channels 

TX absence seizure

ADJUNCT TX Focal seizures (adults and children >2Y/O), Generalized seizures

7

Topiramate

Epilepsy

ADJUNCT TX Focal seizures

8

Divalproex sodium

Anticonvulsant 

PROPHYLAXIS: Migraine

9

Azithromycin

ABX→Macrolides

Similiar to Erythromycin

  • < Strep and staph coverage
  • > Atypical mycobacterial and H. influenzae

10

Gabapentin

Epilepsy

TX (newly diagnosed) Focal seizures, and peripheral neuropathy

ADJUNCT TX Refractory seizures

11

Acyclovir

Antivirals→Guanosine analogs

TX HSV infection 

 

12

Morphine

OPIATE→Strong Agonist

13

Clindamycin

ABX→Lincosamides

TX Anaerobic or polymicrobial infections

14

Sumatriptan

HA→Triptan (Migraine-specific)

TX 1st LINE moderate/severe migraine

15

Phenytoin

Epilepsy→Prolonged inactivation of VG Na+ channels

TX focal/generalized seizures, Status epilepticus 

16

Folic Acid

TX megaloblastic anemias

(pregnancy protection against neural tube defect)

17

Calcium

TX hypocalcemia

18

Valacyclovir

Antivirals→Guanosine analogs

TX HSV infection 

19

Sulfamethoxazole/Trimethoprim

ABX→Sulfonamides

TX Pneumocystis cariniiBacterial diarrhea

2nd LINE TX CAP, UTI, prostatitis, Acute otitis media

PROPHYLAXIS UTI

20

Meloxicam

NSAID→Oxicam (dose dependent)

TX Arthritis

21

Doxycycline

ABX→Inhibition of RNA/DNA synthesis→30s→Tetracycline

TX multi-drug regimen for anthrax, chlamydia, cervicitis, urethritis, CAP, Lyme disease, chronic prostatitis, sinusitis, PID, acne, rosacea, rickettsia infection

22

Ergocalciferol

TX hypocalcemia, Vitamin D deficiency, postmenopausal osteoporsis, renal failure

23

Magnesium 

Anticonvulsant 

TX immediate control of life-threatening convulsions in severe toxemia (pregnancy-related), acute nephritis (children), electrolyte replacement  (hypomagnesia)

24

Hydrocodone Bitartrate/Acetaminophen

OPIATE→Mild/Moderate Agonist

TX pain relief (less efficacious than morphine, given with ASA and APAP)

25

Ibuprofen

NSAID→Propionic Acid

MSK and joint pain, mild/moderate analgesia, fever relief

26

Tramadol

OPIATE> Weak agonist (Blocks reuptake of serotonin and NE)

TX pain relief

27

Acetaminophen

NSAID

Antipyretic, anti-inflammatory (weak), analgesic (NO antiplatelet effects)

28

Levetiracetam

Epilepsy

TX Focal, Generalized seizures

29

Levofloxacin

ABX→Quinolones (Fluoroquinolones)

TX Inhalation anthrax infection

30

Zolpidem

GABA agonist→Benzodiazepine 

TX Sleep enhancers (insomina)

31

Celecoxib

NSAID→COX-2 inhibitor

TX RA, OA, AS, juvenile RA, acute pain (adults)

32

Fluconazole

Antifungal→Azoles Triazole

TX vaginal candidasis

33

Oxycodone

OPIATE→Mild/Moderate Agonist

TX pain relief (less efficacious than morphine, given with ASA and APAP)

34

Hydroxychloroquine sulfate

RA→DMARDs (Nonbiologic)

TX RA, antimalarial (mild disease/combination, reserved for RA unresponsive to NSAIDs - not 1st lINE)

35

Oxcarbazepine

Epilepsy

TX Focal, secondarily generalized (tonic-clonic) seizure

36

Nystatin

Antifungal→Polyene ABX

TX candidiasis (skin, mucous membrane)

37

Ciprofloxacin

ABX→Quinolones (fluoroquinolones)

PROPHYLAXIS Anthrax (post-exposure) 

38

Benztropine

Muscarinic agonist

TX Parkinson disease 

39

Amoxicillin

ABX→Inhibition of Cell Wall Synthesis→Penicilin→Aminopenicillin

TX URI (sinusitis, otitis), UTI (uncomplicated), meningitis, salmonella spp. (NOT 1st LINE)

BACTERIA Gram-negative cocci, Enterobacterialacase (NOT Treponema spp. Actinomyces spp.)

40

Pregabalin

Epilepsy

ADJUNCT TX focal onset seizures, peripheral neuropathy, postherpetic neuralgia, fibromyalgia

 

41

Naproxen

NSAID→Propionic Acid

Similiar to Ibuprofen (MSK/joint pain, mild/moderate analgesia, fever relief)