TOP 200 DRUGS

Question 1

Diclofenac

Answer 1

NSAID→Acetic acids

RA, OA, Ankylosing spondylitis

Question 2

Trazadone

Answer 2

Newer Antidepressants

TX depression and sedative (migraine prevention)

Question 3

Ropinirole

Answer 3

Parkinson’s

TX Parkinson disease (monotherapy for early, adjunct tx for advanced)

Question 4

Aspirin

Answer 4

NSAID→Salicylate

Prophylactically: DEC incidence of CVD (MI, unstable angina)

LOW DOSE: Antipyretic, Analgesic

HIGH DOSE: Anti-inflammatory

Chronic usage: CA prevention

Question 5

Ferrous sulfate

Answer 5

TX iron deficiency anemia

Question 6

Lamotrigine

Answer 6

Epilepsy→Prolonged inactivation of VG Na+ channels

TX absence seizure

ADJUNCT TX Focal seizures (adults and children >2Y/O), Generalized seizures

Question 7

Topiramate

Answer 7

Epilepsy

ADJUNCT TX Focal seizures

Question 8

Divalproex sodium

Answer 8

Anticonvulsant

PROPHYLAXIS: Migraine

Question 9

Azithromycin

Answer 9

ABX→Macrolides

Similiar to Erythromycin

• < Strep and staph coverage
• > Atypical mycobacterial and H. influenzae

Question 10

Gabapentin

Answer 10

Epilepsy

TX (newly diagnosed) Focal seizures, and peripheral neuropathy

ADJUNCT TX Refractory seizures

Question 11

Acyclovir

Answer 11

Antivirals→Guanosine analogs

TX HSV infection

Question 12

Morphine

Answer 12

OPIATE→Strong Agonist

Question 13

Clindamycin

Answer 13

ABX→Lincosamides

TX Anaerobic or polymicrobial infections

Question 14

Sumatriptan

Answer 14

HA→Triptan (Migraine-specific)

TX 1st LINE moderate/severe migraine

Question 15

Phenytoin

Answer 15

Epilepsy→Prolonged inactivation of VG Na+ channels

TX focal/generalized seizures, Status epilepticus

Question 16

Folic Acid

Answer 16

TX megaloblastic anemias

(pregnancy protection against neural tube defect)

Question 17

Calcium

Answer 17

TX hypocalcemia

Question 18

Valacyclovir

Answer 18

Antivirals→Guanosine analogs

TX HSV infection

Question 19

Sulfamethoxazole/Trimethoprim

Answer 19

ABX→Sulfonamides

TX Pneumocystis carinii, Bacterial diarrhea

2nd LINE TX CAP, UTI, prostatitis, Acute otitis media

PROPHYLAXIS UTI

Question 20

Meloxicam

Answer 20

NSAID→Oxicam (dose dependent)

TX Arthritis

Question 21

Doxycycline

Answer 21

ABX→Inhibition of RNA/DNA synthesis→30s→Tetracycline

TX multi-drug regimen for anthrax, chlamydia, cervicitis, urethritis, CAP, Lyme disease, chronic prostatitis, sinusitis, PID, acne, rosacea, rickettsia infection

Question 22

Ergocalciferol

Answer 22

TX hypocalcemia, Vitamin D deficiency, postmenopausal osteoporsis, renal failure

Question 23

Magnesium

Answer 23

Anticonvulsant

TX immediate control of life-threatening convulsions in severe toxemia (pregnancy-related), acute nephritis (children), electrolyte replacement (hypomagnesia)

Question 24

Hydrocodone Bitartrate/Acetaminophen

Answer 24

OPIATE→Mild/Moderate Agonist

TX pain relief (less efficacious than morphine, given with ASA and APAP)

Question 25

Ibuprofen

Answer 25

NSAID→Propionic Acid **MSK and joint pain**, **mild/moderate** **analgesia**, **fever** relief

Question 26

Tramadol

Answer 26

OPIATE\> Weak agonist (Blocks reuptake of serotonin and NE) TX **pain relief**

Question 27

Acetaminophen

Answer 27

NSAID Antipyretic, anti-inflammatory (weak), analgesic (NO antiplatelet effects)

Question 28

Levetiracetam

Answer 28

Epilepsy TX **Focal, Generalized seizures**

Question 29

Levofloxacin

Answer 29

ABX→Quinolones (Fluoroquinolones) TX **Inhalation anthrax infection**

Question 30

Zolpidem

Answer 30

GABA agonist→Benzodiazepine TX **Sleep enhancers (insomina)**

Question 31

Celecoxib

Answer 31

NSAID→COX-2 inhibitor TX **RA, OA, AS, juvenile RA, acute pain (adults)**

Question 32

Fluconazole

Answer 32

Antifungal→Azoles Triazole TX **vaginal candidasis**

Question 33

Oxycodone

Answer 33

OPIATE→Mild/Moderate Agonist TX pain relief (less efficacious than morphine, given with ASA and APAP)

Question 34

Hydroxychloroquine sulfate

Answer 34

RA→DMARDs (Nonbiologic) TX **RA, antimalarial** (mild disease/combination, reserved for RA unresponsive to NSAIDs - not 1st lINE)

Question 35

Oxcarbazepine

Answer 35

Epilepsy TX **Focal, secondarily generalized** (tonic-clonic) **seizure**

Question 36

Nystatin

Answer 36

Antifungal→Polyene ABX TX **candidiasis** (skin, mucous membrane)

Question 37

Ciprofloxacin

Answer 37

ABX→Quinolones (fluoroquinolones) PROPHYLAXIS **Anthrax** (post-exposure)

Question 38

Benztropine

Answer 38

Muscarinic agonist TX **Parkinson disease**

Question 39

Amoxicillin

Answer 39

ABX→Inhibition of Cell Wall Synthesis→Penicilin→Aminopenicillin TX **URI** (sinusitis, otitis), **UTI** (uncomplicated), **meningitis**, *salmonella spp*. (NOT 1st LINE) BACTERIA **Gram-negative cocci, Enterobacterialacase** (NOT *Treponema* spp. *Actinomyces* spp.)

Question 40

Pregabalin

Answer 40

Epilepsy ADJUNCT TX **focal onset seizures, peripheral neuropathy, postherpetic neuralgia, fibromyalgia**

Question 41

Naproxen

Answer 41

NSAID→Propionic Acid Similiar to Ibuprofen (MSK/joint pain, mild/moderate analgesia, fever relief)