Top 200 Drugs Contraindications

Question 1

Contraindications of atorvastatin

Answer 1

Hypersensitivity to atorvastatin
use in breastfeeding
active liver disease
unexplained persistent elevations of serum transaminases
(drug-drug interaction CYP inhibitors/inducers)

Question 2

Contraindications for dapagliflozin

Answer 2

severe renal impairment
(avoid in combination w/ DPP4s)

Question 3

Contraindications for dulaglutide

Answer 3

1) Family history of medullary thyroid carcinoma
2) MEN2

Question 4

Contraindications for empagliflozin

Answer 4

hypersensitivity to empagliflozin

Question 5

Contraindications of ezetimibe

Answer 5

Hypersensitivity to ezetimibe
gallbladder disease
severe hepatic dysfunction
concurrent use with a statin in a pregnant or nursing mother

Question 6

Contraindications of fenofibrate

Answer 6

Hypersensitivity, gallbladder disease, severe renal or hepatic dysfunction, nursing mothers

Question 7

Contraindications of gemfibrozil

Answer 7

Hypersensitivity to gemfibrozil, concurrent repaglinide or simvastatin, gallbladder disease, severe renal or hepatic dysfunction
(not with statin)

Question 8

Contraindications of liraglutide

Answer 8

Hypersensitivity, multiple endocrine neoplasia syndrome type 2, history or family history of medullary thyroid carcinoma

Question 9

Contraindications of lovastatin

Answer 9

Hypersensitivity to lovastatin
active liver disease
use in breastfeeding
concomitant use with strong CYP3A4/5 inhibitors
unexplained persistent elevation of liver enzymes

Question 10

Contraindications of glimepiride

Answer 10

Hypersensitivity to sulfonylureas, diabetic ketoacidosis

Question 11

Contraindications of metformin

Answer 11

1)Hypersensitivity to metformin
2) contrast media
3) eGFR <30 mL/min/1.73 m2
4) metabolic acidosis

Question 12

Contraindications for glipizide

Answer 12

1) Hypersensitivity to sulfonylureas
2) diabetic ketoacidosis
3) type 1 diabetes

Question 13

Contraindications for insulin aspart

Answer 13

1) hypersensitivity
2) hypoglycemic episode

Question 14

Contraindications for insulin degludec

Answer 14

1) hypersensitivity
2) hypoglycemic episode

Question 15

Contraindications for insulin glargine

Answer 15

1) hypersensitivity
2) hypoglycemic episode

Question 16

Contraindications of insulin human

Answer 16

1) hypersensitivity
2) hypoglycemic episode

Question 17

Contraindications of insulin isophane human

Answer 17

1) hypersensitivity
2) hypoglycemic episode

Question 18

Contraindications for insulin lispro

Answer 18

1) hypersensitivity
2) hypoglycemic episode

Question 19

Contraindications for metformin/sitagliptin

Answer 19

Renal dysfunction
Metabolic acidosis

Question 20

Contraindications for pioglitazone

Answer 20

1) Hypersensitivity to pioglitazone
2) NYHA III/IV heart failure

Question 21

Contraindications for pravastatin

Answer 21

1) Hypersensitivity to pravastatin
2) use in breastfeeding
3) active liver disease

Question 22

Contraindications for rosuvastatin

Answer 22

1) Hypersensitivity to rosuvastatin
2) active liver disease
3) use in breastfeeding

Question 23

Contraindications for semaglutide

Answer 23

1) hypsersensitivity
2) familial history of thyroid cancers

Question 24

Contraindications for simvastatin

Answer 24

1) Hypersensitivity to simvastatin
2) active liver disease
3) use in breastfeeding

Question 25

Contraindications for sitagliptin

Answer 25

1) hypersensitivity

Question 26

Contraindications for amlodipine

Answer 26

hypersensitivity to amlodipine

Question 27

Contraindications for amlodipine-benazepril

Answer 27

history of angioedema anuria

Question 28

Contraindications for atenolol

Answer 28

hypersensitivity to atenolol sinus bradycardia 2nd or 3rd degree AV block overt heart failure or cardiogenic shock

Question 29

Contraindications for benazepril

Answer 29

hypersensitivity to benazepril history of angioedema anuria concurrent use with aliskiren in patients with diabetes mellitus concurrent sacubitril

Question 30

Contraindications for carvedilol

Answer 30

Hypersensitivity bronchial asthma severe sinus bradycardia 2nd- or 3rd-degree AV block sick sinus syndrome overt heart failure cardiogenic shock severe hepatic impairment

Question 31

Contraindications for chlorthalidone

Answer 31

hypersensitivity to chlorthalidone or sulfa drugs anuria

Question 32

Contraindications for clonidine

Answer 32

hypersensitivity to clonidine

Question 33

Contraindications for furosemide

Answer 33

hypersensitivity to furosemide anuria

Question 34

Contraindications for hydralazine

Answer 34

hypersensitivity to hydralazine dissecting aortic aneurism coronary artery disease mitral valve rheumatic heart disease

Question 35

Contraindications for hydrochlorothiazide

Answer 35

hypersensitivity to hydrochlorothiazide or sulfonamide concomitant dofetilide therapy anuric patients

Question 36

Contraindications for lisinipril-HCTZ

Answer 36

sulfa drugs anuria history of angioedema

Question 37

Contraindications for losartan-HCTZ

Answer 37

sulfa drugs anuria aliskiren pregnancy

Question 38

Contraindications for irbesartan

Answer 38

hypersensitivity to irbesartan pregnancy concomitant use with aliskiren

Question 39

Contraindications for lisinopril

Answer 39

hypersensitivity to lisinopril or other ACE inhibitors history of ACE-induced angioedema hereditary or idiopathic angioedema concurrent use with aliskiren concurrent use with sacubitril

Question 40

Contraindications for losartan

Answer 40

hypersensitivity to losartan or other angiotension II receptor antagonists pregnancy

Question 41

Contraindications for metoprolol

Answer 41

hypersensitivity to metoprolol severe bradycardia 2nd or 3rd degree AV block sick sinus syndrome decompensated heart failure cardiogenic shock

Question 42

Contraindications for nifedipine

Answer 42

hypersensitivity to nifedipine cardiogenic shock STEMI concurrent use of CYP3A4/5 inducers

Question 43

Contraindications for olmesartan

Answer 43

hypersensitivity to Olmesartan or other ARB pregnancy concurrent use with aliskiren in diabetes patients

Question 44

Contraindications for prazosin

Answer 44

hypotension

Question 45

Contraindications for propanolol

Answer 45

hypersensitivity to propranolol asthma sinus bradycardia AV block sick sinus syndrome cardiogenic shock

Question 46

Contraindications for spironolactone

Answer 46

hypersensitivity to spironolactone anuria acute renal insufficiency hyperkalemia

Question 47

Contraindications for triamterene-HCTZ

Answer 47

hypersensitivity to hydrochlorothiazide, sulfonamides, triamterene concomitant use of potassium supplements, potassium containg salt substitutes, or other potassium sparing diuretics anuria acute/chronic renal insufficiency hyperkalemia

Question 48

Contraindications for valsartan

Answer 48

hypersensitivity to valsartan pregnancy concurrent use with aliskiren in patient with diabetes