Top 300 Flashcards

(300 cards)

1
Q

Metronidazole

A

Flagyl, Flagyl ER

Antibacterial, Antiprotozoal

Finish course as prescribed. Avoid alcohol during therapy and for 2 days after. May discolor urine reddish-brown.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Fluconazole

A

Diflucan

Antifungal

Finish course as prescribed. May cause headache and GI upset. CYP interactions: strongly inhibits 2C9, 2C19 (ex. Clopidogrel, warfarin and phenytoin); moderately inhibits 3A4. May prolong QT interval.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Ketoconazole

A

Nizoral

Antifungal

Available topically and orally. Tablets should be taken with food. Drug is absorbed best in acidic conditions; avoid antacids, PPI’s and H2 blockers for 2 hours before and after administration. Major CYP 3A4 drug interactions. Topical formulations are flammable. Potential for hepatotoxicity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Nystatin

A

Mycostatin, Nystop

Antifungal

Available in many different dosage forms (topical, oral, suspension, powder) and some combination products. Suspension can be dosed as “swish and spit” for oral candidiasis or “swish and swallow” for esophageal candidiasis.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Terbinafine

A

Lamisil

Antifungal

Finish course as prescribed. Topical formulation available OTC and is most common use.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Acyclovir

A

Zovirax

Antiviral against HSV

Available topically and orally. Avoid intercourse during herpes outbreaks. Dose and duration depends on indication. CNS side-effects especially in elderly and renal impairment. Interacts with herpes zoster vaccine. Stay well hydrated.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Valacyclovir

A

Valtrex

Antiviral against HSV

Avoid intercourse during herpes outbreaks. Dose and duration depends on indication. CNS side-effects especially in elderly and renal impairment. Interacts with herpes zoster vaccine. Stay well hydrated.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Cephalexin

A

Keflex

Cephalosporin antibiotic, 1st generation

Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Cefuroxime axetil

A

Ceftin

Cephalosporin antibiotic, 2nd generation

Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Cefdinir

A

Omnicef

Cephalosporin antibiotic, 3rd generation

Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Ciprofloxacin

A

Cipro (XR)

Fluoroquinolone antibiotic

Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic and otic suspensions.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Levofloxacin

A

Levaquin

Fluoroquinolone antibiotic

Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic suspension.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Moxifloxacin

A

Avelox

Fluoroquinolone antibiotic

Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic solution (Vigamox, Moxeza).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Azithromycin

A

Zithromax, Zmax, Azasite

Macrolide antibiotic

Finish course as prescribed. No CYP 3A4 inhibition. QT prolongation possible. Opthalmic solution, Azasite, is refrigerated.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Clarithromycin

A

Biaxin (XL)

Macrolide antibiotic

Finish course as prescribed. May impart metallic taste. Inhibits CYP 3A4. QT prolongation possible.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Clindamycin

A

Cleocin, Cleocin T, Evoclin, Clindagel

Available in many dosage forms (oral, topical, vaginal suppository, powder for suspension) and combination products. Oral therapy may cause C. diff-associated severe diarrhea. Suspension has horrible taste, little flavoring options available.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Nitrofurantoin

A

Macrobid, Macrodantin, Furadantin

Take with food to enhance absorption. May cause peripheral neuropathy or pulmonary fibrosis. Shake suspension thoroughly.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Amoxicillin

A

Amoxil

Penicillin antibiotic

Finish course as prescribed. May cause GI upset; take with food. Hypersensitivity reactions possible. May decrease efficacy of oral contraceptives. Secondary vaginal yeast infection may develop. Shake susp well and keep refrigerated, note exp date after reconstitution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Amoxicillin + Clavulanate

A

Augmentin, Augmentin XR

Penicillin antibiotic

Finish course as prescribed. May cause GI upset; take with food. More likely to have diarrhea b/c of clavulanate- maintain hydration. Clavulanic acid doses vary among formulations; double-check if using alternate formulation to achieve prescribed dose (ex. 400mg-57mg/5ml suspension cannot be substituted for 600mg-42.9mg/5ml suspension). Shake susp well and keep refrigerated, note exp date after reconstitution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Penicillin V Potassium

A

Veetids, Pen-Vee K

Penicillin antibiotic

Finish course as prescribed. May cause GI upset; take with food. C. diff-associated diarrhea may develop. Hypersensitivity reactions possible.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Sulfamethoxazole + Trimethoprim

A

Bactrim, Bactrim DS, Septra, Septra DS

Sulfonamide antibacterial

Finish course as prescribed. Take with plenty of water. Increases sensitivity to sunlight. Increased risk of hypoglycemia if taken with other sulfonylureas. Severe life-threatening skin reactions possible.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Doxycycline

A

Vibramycin, Doryx, Adoxa, Monodox, Oracea, Periostat

Tetracycline antibiotic

May increase sensitivity to sunlight. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). Hyclate and monohydrate salts not interchangeable.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Metronidazole

A

Metrogel, Metrogel-Vaginal, Metrocream, Metrolotion

Topical antibiotic

Use condoms during vaginal therapy. Some drug is absorbed systemically; avoid alcohol consumption during therapy and for 2 days after. Also used topically on the face for rosacea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Mupirocin

A

Bactroban

Topical antibiotic

Used most in hospital to reduce the risk of MRSA infection from carriers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Nystatin + Triamcinolone
Mycolog II Topical antifungal + steroid combination Use a sparing amount, avoid application around eyes.
26
Chlorhexidine Gluconate
Peridex, PerioGard Tx for gingivitis/Periodontitis Swish/spit 15 mls BID
27
Olsetamivir
Tamiflu antiviral against influenza BID dosing for Tx, QD dosing for prophylaxis, tx within 24-48 hours of sx, rarely causes behavioral disturbances inc delirium, risk of anaphylaxis and allergic skin rxns
28
Emtricitabine + Tenofovir
Truvada Reverse transcriptase inhibitor Adherence important to prevent resistance. May be taken without regard to food. May cause decrease in bone mineral density, fat redistribution, lactic acidosis, hepatomegaly, and renal toxicity. Recently approved for pre-exposure HIV prophylaxis for those whose partner has HIV; must have regular testing every 3 months.
29
Zidovudine + Lamivudine
Combivir Reverse transcriptase inhibitor Adherence important to prevent resistance. May be taken without regard to food. May cause fat redistribution, lactic acidosis, hepatomegaly, myopathy, and hematologic toxicity.
30
Enalapril
Vasotec ACE Inhibitor, antihypertensive Pregnancy category D. May cause a dry cough, first-dose hypotension (especially in CHF and hypervolemia) and hyperkalemia (avoid salt substitutes). Angioedema is a serious reaction; discontinue immediately and medical intervention may be necessary. Drug has renoprotective properties, but may also cause acute renal failure; monitor serum creatinine and discontinue if >30% increase.
31
Ramipril
Altace ACE Inhibitor, antihypertensive Pregnancy category D. May cause a dry cough, first-dose hypotension (especially in CHF and hypovolemia) and hyperkalemia (avoid salt substitutes). Angioedema is a serious reaction; discontinue immediately and medical intervention may be necessary. Drug has renoprotective properties, but may also cause acute renal failure; monitor serum creatinine and discontinue if >30% increase. May have greater benefit if dosed at bedtime.
32
Quinapril
Accupril, Accuretic ACE Inhibitor, antihypertensive; Accuretic-combo with HCTZ Pregnancy category D. May cause a dry cough, first-dose hypotension (especially in CHF and hypovolemia) and hyperkalemia (avoid salt substitutes). Angioedema is a serious reaction; discontinue immediately and medical intervention may be necessary. Drug has renoprotective properties, but may also cause acute renal failure; monitor serum creatinine and discontinue if >30% increase.
33
Benazepril, Ben/HCTZ
Lotensin, Lotensin HCT ACE Inhibitor, antihypertensive; HCT-combo with HCTZ Pregnancy category X. May cause a dry cough, first-dose hypotension (especially in CHF and hypovolemia) and hyperkalemia (avoid salt substitutes). Angioedema is a serious reaction; discontinue immediately and medical intervention may be necessary. Drug has renoprotective properties, but may also cause acute renal failure; monitor serum creatinine and discontinue if >30% increase.
34
Lisinopril, Lis/HCTZ
Zestril or Prinivil, Zestoretic ACE Inhibitor, antihypertensive; Zestoretic-combo with HCTZ Pregnancy category D. May cause a dry cough, first-dose hypotension (especially in CHF and hypovolemia) and hyperkalemia (avoid salt substitutes). Angioedema is a serious reaction; discontinue immediately and medical intervention may be necessary. Drug has renoprotective properties, but may also cause acute renal failure; monitor serum creatinine and discontinue if >30% increase.
35
Doxazosin Mesylate
Cardura, Cardura XL Alpha 1 Blocker antihypertensive, also used in BPH May cause postural hypotension/orthostasis after first dose or an increase in dose. Dizziness and headache common.
36
Terazosin
Hytrin Alpha 1 Blocker antihypertensive, also used in BPH May cause postural hypotension/orthostasis after first dose or an increase in dose. Dizziness and headache common.
37
Clonidine
Catapres, Catapres TTS, Nexiclon XR, Kapvay ER Alpha II agonist, antihypertensive May cause drowsiness, dry mouth, or skin reactions. Rotate patch application sites and discard patches carefully. Do not discontinue abruptly.
38
Amiodarone
Cordarone Antiarrhythmic Many drug interactions, complicated by extremely long half life of 40-50 days. Hepatic and pulmonary damage possible; notify MD if jaundice, dark urine or trouble breathing occur. May cause thyroid problems, hypotension, bradycardia, ocular disease and exacerbate arrhythmia. Have regular ophthalmic visits. May cause skin to turn bluish-grey in color
39
Warfarin Sodium
Coumadin Anticoagulant Risk of bleeding, especially GI. Very narrow therapeutic index; INR must be monitored regularly and vitamin K intake should be uniform. Many drug interactions; always check with MD or RPh when taking a new medication.
40
Fenofibrate
TRICOR, Trilipix Antihyperlipidemic Risk of myopathy; taking with statins increase risk. Discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Increases action of sulfonylureas; monitor for hypoglycemia. No good outcome data; FIELD and ACCORD Lipid were not positive. Safer to combine with a statin than gemfibrozil, but not evidence based. Many different "Brand" formulations.
41
Gemfibrozil
Lopid Antihyperlipidemic Increases effects of statins and therefore myopathy risk; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Should be taken 30 minutes before breakfast and dinner. Increased risk of gall stones.
42
Niacin
Niaspan ER Antihyperlipidemic Causes flushing in most individuals (>80%); take at bedtime with a low-fat snack and 325mg aspirin to reduce effects. Doses higher than 2g/day may cause hepatotoxicity.
43
Atorvastatin
Lipitor Antihyperlipidemic - HMG CoA reductase inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. May be taken at any time of day. Avoid excessive alcohol and grapefruit juice. Some CYP 3A4 interactions.
44
Lovastatin
Mevacor, Altoprev ER Antihyperlipidemic - HMG CoA reductase inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Take in the evening. Avoid excessive alcohol and grapefruit juice. Several CYP 3A4 interactions.
45
Pravastatin
Pravachol Antihyperlipidemic - HMG CoA reductase inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Avoid excessive alcohol. Significantly fewer drug interactions compared to other statins (cleared by kidney rather than liver).
46
Rosuvastatin
Crestor Antihyperlipidemic - HMG CoA reductase inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. May be taken at any time of day. Avoid excessive alcohol and grapefruit juice.
47
Simvastatin/ezetimibe
Vytorin Antihyperlipidemic - HMG CoA reductase inhibitor and cholesterol absorption inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Take in the evening. Avoid excessive alcohol and grapefruit juice. Several CYP 3A4 interactions. Lacks data that combination is superior to simvastatin alone.
48
Simvastatin
Zocor Antihyperlipidemic - HMG reductase inhibitor Pregnancy category X. Myopathy is a serious reaction; discontinue immediately and report any signs (muscle pain, brown urine) to MD and/or RPh. Take in the evening. Avoid excessive alcohol and grapefruit juice. Several CYP 3A4 interactions.
49
Aspirin
Ecotrin Antiplatelet Used for cardiovascular or cerebrovascular accident treatment/prophylaxis. 75-325 mg pod daily. Risk/benefit important for prophylaxis decisions. Increased risk of bleeding. Be aware of hypersensitivity reactions especially in patients with allergic triad of as a allergy, nasal polyps, and asthma, avoid in children due to risk of Reye syndrome.
50
Amlodipine + Valsartan
Exforge, Exforge HCT ARB + calcium channel blocker combo; HCT also contains diuretic
51
Valsartan, Val/HCTZ
Diovan, Diovan HCT ARB Antihypertensive, HCT also contains diuretic Black box warning in pregnancy. May cause dizziness, hypotension, hyperkalemia (avoid salt substitutes, potassium sparing diuretics), and renal dysfunction (discontinue if serum creatinine increases >30%). NSAIDs reduce antihypertensive effect and increase risk of renal dysfunction. Taking with ACE inhibitor or renin inhibitor increases side effects with little benefit.
52
Irbesartan, Irbesartan/HCTZ
Avapro, Avalide ARB Antihypertensive; Avalide-combo with diuretic Black box warning in pregnancy. May cause dizziness, hypotension, hyperkalemia (avoid salt substitutes, potassium sparing diuretics), and renal dysfunction (discontinue if serum creatinine increases >30%). NSAIDs reduce antihypertensive effect and increase risk of renal dysfunction. Taking with ACE inhibitor or renin inhibitor increases side effects with little benefit.
53
Candesartan, Can/HCTZ
Atacand, Atacand HCT ARB Antihypertensive; HCT-combo with diuretic Black box warning in pregnancy. May cause dizziness, hypotension, hyperkalemia (avoid salt substitutes, potassium sparing diuretics), and renal dysfunction (discontinue if serum creatinine increases >30%). NSAIDs reduce antihypertensive effect and increase risk of renal dysfunction. Taking with ACE inhibitor or renin inhibitor increases side effects with little benefit.
54
Olmesartan
Benicar, Benicar HCT ARB Antihypertensive; HCT-combo with diuretic Black box warning in pregnancy. May cause dizziness, hypotension, hyperkalemia (avoid salt substitutes, potassium sparing diuretics), and renal dysfunction (discontinue if serum creatinine increases >30%). NSAIDs reduce antihypertensive effect and increase risk of renal dysfunction. Taking with ACE inhibitor or renin inhibitor increases side effects with little benefit. Sprue -like enteropathy (unexplained wt loss and diarrhea)
55
Losartan, Los/HCTZ
Cozaar, Hyzaar ARB Antihypertensive; Hyzaar-combo with diuretic Black box warning in pregnancy. May cause dizziness, hypotension, hyperkalemia (avoid salt substitutes, potassium sparing diuretics), and renal dysfunction (discontinue if serum creatinine increases >30%). NSAIDs reduce antihypertensive effect and increase risk of renal dysfunction. Taking with ACE inhibitor or renin inhibitor increases side effects with little benefit.
56
Atenolol
Tenormin Beta Blocker, Beta-1 Selective May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly. Limited evidence/data.
57
Metoprolol Succinate
Toprol XL Beta Blocker, Beta-1 Selective May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly. Succinate and tartrate salts are not interchangeable!
58
Metoprolol Tartrate
Lopressor Beta Blocker, Beta-1 selective May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly. Succinate and tartrate salts are not interchangeable!
59
Bisoprolol, Bisoprolol + HCTZ
Zebeta, Ziac Beta Blocker, Beta-1 selective; Ziac is combo with diuretic May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly due to risk of tachycardia and hypertension. Bisoprolol has outcome data in heart failure; target dose of 10mg/day
60
Atenolol/chlorthalidone
Tenoretic Beta Blocker, Beta-1 Selective/ thiazide diuretic
61
Propranolol
Inderal, Inderal LA, Innopran, Innopran XL Beta Blocker, nonselective May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly. LA and immediate release formulations are not mg-mg equivalent; dose may need to be increased by up to 30% when converting from immediate release to LA.
62
Carvedilol
Coreg (CR) Beta Blocker, nonselective; Alpha-1 blocker May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly. CR and immediate release formulations are not mg-mg equivalent; CR 10mg equivalent to 3.125mg BID of immediate release.
63
Labetalol
Normodyne or Trandate Beta Blocker, nonselective; Alpha-1 blocker May cause drowsiness. Masks symptoms of hypoglycemia. Do not discontinue abruptly.
64
Digoxin
Lanoxin or Lanoxicap Cardiac glycoside: + Inotropic, - chronotropic Narrow therapeutic index, many drug interactions. Digoxin toxicity possible (anorexia, nausea, fatigue, vision disturbances, bradycardia, arrhythmias).
65
Amlodipine + Olmestartan
Azor, Tribenzor Combination of ARB + calcium channel blocker; Tribenzor also contains diuretic
66
Amlodipine
Norvasc Dihydro calcium channel blocker May cause drowsiness, risk of hypotension and orthostasis. Risk of peripheral edema that is not responsive to diuretics but may be relieved by ACEi or ARB.
67
Nifedipine
Procardia, Procardia XL, Adalat CC Dihydro calcium channel blocker May cause drowsiness. Risk of peripheral edema that is not responsive to diuretics; ACEi or ARB used to reverse. Adalat and Procardia not equivalent, double-check when dispensing generics.
68
Amlodipine + Benazepril
Lotrel Dihydro calcium channel blocker + ACE inhibitor combo
69
Amlodipine + Atorvastatin
Caduet Dihydro calcium channel blocker + HMG-CoA reductase inhibitor combo trate amlodipine to response over 1-2 weeks and atorvastatin in 6-8 weeks
70
Dabigatran
Pradaxa Direct thrombin inhibitor Monitor for bleeding. May cause some GI upset. Store capsules in original container or blister pack; discard unused medication after 4 months. Do not crush, chew or open capsules. If a dose is missed, do not take a double dose if more than 6 hours have passed. Drug interactions with p-glycoprotein substrates (dronedarone, ketoconazole, rifampin). Dose should be adjusted for kidney function. Discontinuation for surgery determined by creatinine clearance
71
Potassium Chloride
Klor-Con Electrolyte supplement May cause GI upset, take with food. Monitor salt intake.
72
Rivaroxaban
Xarelto Factor Xa inhibitor Monitor for bleeding. Doses of 15 mg or more must be taken with food. Compliance extremely important, but do not take a double dose if a dose is missed. Discontinue at least 24 hours before surgeries. Drug interactions with CYP 3A4 substrates, but benefit outweighs cost in some cases.
73
Apixaban
Eliquis Factor Xa inhibitor Monitor for bleeding. 5 mg orally twice daily. A dose of 2.5 mg twice daily is recommended for patients at least 80 years old, who weigh no more than 60 kg, or who have serum creatinine of at least 1.5 mg/dL, as well as those receiving strong dual inhibitors of cytochrome P450 3A4 and P-glycoprotein. Boxed warning - inc risk of stroke if DC'd. Not indicated in patients with prosthetic heart valves.
74
Furosemide
Lasix Loop diuretic May cause hypokalemia; monitor potassium levels and kidney function. Also watch salt intake. May be used as needed in congestive heart failure. Hypersensitivity reaction may occur in individuals with sulfa allergy. Lasix short for "last six hours".
75
Enoxaparin
Lovenox Low molecular weight heparin Increased risk of bleeding. Counsel on injection technique. Often used when beginning warfarin to achieve goal INR more quickly. In community pharmacy, double-check to make sure proper package size and quantity are being dispensed/billed.
76
Isosorbide Mononitrate
Imdur, ISMO Nitroglycerin antianginal/vasodilator Frequently causes dizziness and/or headache. Dosed twice daily, but must be taken "asymmetrically" to prevent tolerance; take second dose 8 hours after first dose rather than every 12 hours.
77
Nitroglycerin SL
Nitrostat Nitroglycerin antianginal/vasodilator Frequently causes dizziness and/or headache. If chest pain persist after first dose, take second dose in 5 minutes. Call 911 if symptoms persist after second dose. Store in original container.
78
Topical Nitroglycerin
Nitro-Dur Nitroglycerin antianginal/vasodilator Finish course as prescribed. Apply patch for 12 hours and remove for 12 hours for nitrate-free period.
79
Diltiazem
Cardizem, Cardizem SR, Cardizem CD, Cardizem LA, Tiazac Non-dihydro Calcium Channel Blocker May cause drowsiness/dizziness or headache. Do not discontinue therapy without discussing with MD. Many formulations that may not be equivalent; double-check when dispensing generics.
80
Verapamil
Calan, Calan SR, Isoptin SR Non-dihydro Calcium Channel Blocker May cause drowsiness/dizziness, headache, or constipation. Do not discontinue therapy without discussing with MD.
81
Clopidogrel
Plavix Platelet Inhibitor Monitor for bleeding. Compliance extremely important. CYP 2C19 inhibitors such as omeprazole and esomeprazole greatly decrease efficacy. Check with MD or RPh before starting new medications or taking OTC medications.
82
Triamterene + HCTZ
Dyazide capsules or Maxzide tablets Potassium-sparing + thiazide diuretic combo Take in the early morning. Monitor renal function, potassium levels, and salt intake; not to be used if renal function impaired. Risk of kidney stones; drink plenty of fluids to reduce risk. Double-check patient profile when dispensing generics; patients should remain on tablets or capsules unless MD changes.
83
Spironolactone, Spir/HCTZ
Aldactone, Aldactazide Potassium-sparing diuretic; Aldactazide also contains diuretic Take in the early morning. Monitor renal function, potassium levels, and salt intake. May cause gynecomastia in males, menstrual irregularities in females (antiandrogenic properties). Evidence-based data for heart failure, post MI, and resistant hypertension. Aldactazide may cause hypersensitivity reactions in individuals with sulfa allergy.
84
Indapamide
Lozol Thiazide diuretic Take in the early morning. Monitor renal function, potassium levels, and salt intake; not to be used in severe renal impairment, but may be used in minimally impaired renal function. Hypersensitivity reaction may occur in individuals with sulfa allergy.
85
Chlorthalidone
Thalidone, Hygroton Thiazide diuretic Take in the early morning. Monitor renal function, potassium levels, and salt intake; not to be used if renal function impaired. Hypersensitivity reaction may occur in individuals with sulfa allergy. Chlorthalidone is twice as potent as HCTZ.
86
Hydrochlorothiazide (aka HCTZ)
Oretic, Microzide Thiazide diuretic Take in the early morning. Monitor renal function, potassium levels, and salt intake. Hypersensitivity reaction may occur in individuals with sulfa allergy.
87
Metolazone
Zaroxolyn Thiazide diuretic Take in the early morning. Monitor renal function, electrolytes (esp. potassium and magnesium) and salt intake. Hypersensitivity reaction may occur in individuals with sulfa allergy. Often used in diuretic-resistant patients in combination with loop diuretics.
88
Ondansetron
Zofran, Zofran ODT 5-HT3 antagonist Antiemetic May cause headache, fatigue. Dissolve ODT under the tongue, store in original container until ready to use. QT prolongation possible.
89
Donepezil
Aricept Acetylcholinesterase inhibitor Take in the evening. Significant nausea, vomiting and diarrhea possible, as well as anorexia. May also cause bradycardia and fainting. Set realistic expectations for Alzheimer's patients. Keep in mind positive statistical significance vs. clinical significance.
90
Rivastigmine
Exelon, Exelon Patch Acetylcholinesterase Inhibitor Take capsules in the evening. Rotate patch application sites. Significant nausea, vomiting and diarrhea possible, as well as anorexia. May also cause bradycardia and fainting. Set realistic expectations for Alzheimer's patients. Keep in mind positive statistical significance vs. clinical significance.
91
Butalbital + aspirin + caffeine, available with or without codeine
Fiorinal, Fiorinal with codeine Analgesic Combo for Tension Headaches, C-III May cause drowsiness or dizziness; avoid alcohol use during therapy. Caution against taking other products containing aspirin.
92
Butalbital + acetaminophen + caffeine (sometimes called B-A-C), available with or without codeine
Fioricet, Fioricet with codeine Analgesic Combo for Tension Headaches, C-III if it has codeine May cause drowsiness or dizziness; avoid alcohol use during therapy. Do not exceed 4g of APAP per day, 3g if frequent alcohol drinker, 2g if taking warfarin. New black box warning with acetaminophen due to hepatotoxicity.
93
Buspirone
Buspar Antianxiety- serotonin 5-HT1A receptor partial agonist May cause drowsiness or dizziness, slow onset, mildly effective, little potential for abuse.
94
Scopolamine
Transderm-Scop Anticholinergic May cause drowsiness or dizziness. wash your hands after application as touching your eyes after application may result in blurred vision (dilation)
95
Mirtazapine
Remeron Antidepressant May cause drowsiness or dizziness, dry mouth, constipation and weight gain. Do not discontinue abruptly. Open from blister and dissolve SolTab on the tongue.
96
Trazodone
Desyrel Antidepressant/Sleep Aid May cause dizziness/drowsiness/orthostasis, priapism risk.
97
Bupropion
Wellbutrin (SR) (XL) or Zyban Antidepressant/smoking cessation aid Take XL tabs in AM to avoid insomnia, do not crush or chew SR or XL tabs, do not take doses too close or exceeding maximum doses because of seizure risk. Potential side-effects inc nervousness, constipation, trouble sleeping, dry mouth, tremor.
98
Carbamazepine
Tegretol (XR) Antiepileptic Take with food, may cause drowsiness, avoid alcohol. Serious and sometimes fatal dermatologic reactions (including Stevens-Johnson syndrome and toxic epidermal necrolysis) have been reported, especially in patients with the inherited allelic variant HLA-B*1502. Genetically at-risk patients (IE those form Asia including China) should be screened prior to receiving carbamazepine.
99
Lamotrigine
Lamictal Antiepileptic Report hypersensitivity/rash to MD, may cause drowsiness, do not operate heavy machine
100
Levetiracetam
Keppra Antiepileptic May cause dizziness/drowsiness, do not operate heavy machinery, do not abruptly discontinue therapy
101
Oxcarbazepine
Trileptal Antiepileptic May cause dizziness/drowsiness, do not operate heavy machinery, do not abruptly discontinue therapy
102
Phenytoin Sodium
Dilantin Kapseals Antiepileptic May cause dizziness/drowsiness, do not operate heavy machinery. Emphasize good oral hygiene to reduce risk of gingival hyperplasia
103
Divalproex
Depakote (ER) Antiepileptic, mood stabilizer Do not abruptly discontinue therapy, avoid alcohol use, may cause drowsiness
104
Phenobarbital
Phenobarbital Antiepileptic/hypnotic; C-IV May cause drowsiness or dizziness, avoid alcohol use during therapy
105
Topiramate
Topamax Antiepileptic/Migraine prophylactic May cause drowsiness or dizziness, avoid alcohol use during therapy. Confusion ("Dopamax") and it is now FDA approved in a combination with phentermine in extended release - Qsymia (C-IV)
106
Gabapentin
Neurontin Antiepileptic/neuropathic analgesic May cause drowsiness or dizziness, avoid alcohol use during therapy. Edema, weight gain and confusion as common side effects, as well as generally need to titrate slowly to higher doses as this agent has dose related kinetics
107
Hydroxyzine hydrochloride
Atarax Antihistamine May cause anticholinergic side-effects.
108
Eletriptan
Relpax Antimigraine, 5-HT1 agonist Take at onset of migraine. If headache is relieved but returns after 1st dose, repeat in 2 hours. Do not exceed 2 doses or 80mg in a 24 hour period. If 1st dose does not relieve symptoms, reevaluate condition. Ischemic cardiovascular events possible. Drug interactions with CYP 3A4 substrates and ergot derivatives.
109
Rizatriptan
Maxalt, Maxalt MLT Antimigraine, 5-HT1 agonist Take at onset of migraine. If headache is relieved but returns after 1st dose, repeat in 2 hours. Do not exceed 2 doses or 30mg in a 24 hour period. If 1st dose does not relieve symptoms, reevaluate condition. Ischemic cardiovascular events possible. Drug interactions with ergot derivatives. Dissolvable tablets contain phenylalanine.
110
Sumatriptan
Imitrex Antimigraine, 5-HT1 agonist Take at onset of migraine. If headache is relieved but returns after 1st dose, repeat in 2 hours. Do not exceed 2 doses or 200mg in a 24 hour period. If 1st dose does not relieve symptoms, reevaluate condition. Ischemic cardiovascular events possible. Drug interactions with ergot derivatives. Available in oral tablet, injection kit, and nasal spray.
111
Benztropine
Cogentin Antiparkinson Agent May take with food to decrease GI symptoms. Potential anticholinergic side-effects
112
Levodopa/Carbidopa
Sinemet (CR) Antiparkinson Agent Avoid products containing B6 as they reduce the effectiveness of levodopa, may be taken with food/milk if GI upset occurs
113
Pramipexole
Mirapex Antiparkinson Agent Hallucinations may occur, report any changes in vision to MD, may cause drowsiness and even sleep attacks (falling asleep without warning)
114
Ropinirole
Requip Antiparkinson/Restless Leg agent May cause drowsiness or dizziness, avoid alcohol use during therapy, orthostasis may occur. May also cause sleep attacks.
115
Olanzapine
Zyprexa Antipsychotic Initially may cause dizziness, use caution when operating heavy machinery due to drowsiness, may cause wt gain, DM and dyslipidemia
116
Quetiapine
Seroquel (XR) Antipsychotic Initially may cause dizziness, use caution when operating heavy machinery due to drowsiness
117
Risperidone
Risperdal Antipsychotic First doses may cause fainting, may impair judgment, avoid alcohol use
118
Ziprasidone
Geodon Antipsychotic May cause arrhythmias, do not discontinue use abruptly, take with food
119
Aripiprazole
Abilify Antipsychotic for bipolar, schizophrenia, and major depressive disorder Avoid alcohol, D/I 3A4, QT prolongation, do not discontinue abruptly
120
Meclizine
Antivert Antivertigo Agent Potential anticholinergic side-effects
121
Alprazolam
Xanax (XR) Benzodiazepine Antianxiety, C-IV Do not exceed prescribed dose, do not take with alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, avoid abrupt discontinuation
122
Clonazepam
Klonopin Benzodiazepine Antianxiety; C-IV Do not exceed prescribed dose, do not take with alcohol, may cause drowsiness/dizziness, do not operate heavy machinery
123
Diazepam
Valium Benzodiazepine Antianxiety; C-IV Do not exceed prescribed dose, do not take with alcohol, may cause drowsiness/dizziness, do not operate heavy machinery
124
Lorazepam
Ativan Benzodiazepine Antianxiety; C-IV Do not exceed prescribed dose, do not take with alcohol, may cause drowsiness/dizziness, do not operate heavy machinery
125
Temazepam
Restoril Benzodiazepine Antianxiety; C-IV Do not exceed prescribed dose, do not take with alcohol, may cause drowsiness/dizziness, do not operate heavy machinery
126
Phentermine
Adipex-P CNS stimulant - Obesity Management; C-IV Cardiovascular risk caution, take in the morning,
127
Methylphenidate
Concerta or Ritalin (ER) or Metadate CD CNS Stimulant for ADD, C-II Take as directed, don’t share your pills
128
Atomoxetine
Strattera CNS Stimulant, used for ADD May impair cognitive & motor function, use caution when operating machinery, not a drug of abuse
129
(Dex)/Amphetamine Mixed salts
Adderall (XR) CNS Stimulant, used for ADD; C-II Take as directed, don’t share your pills
130
Lisdexamfetamine
Vyvanse CNS Stimulant, used for ADHD; C-II Take as directed, don’t share your pills
131
Modafinil
Provigil CNS Stimulant, used for narcolepsy; C-IV Take in morning or 1 hour prior to work, avoid driving until deemed safe by MD
132
Dexmethylphenidate
Focalin (XR) CNS stimulant; C-II Take as directed, don’t share your pills
133
Zaleplon
Sonata hypnotic, nonbenzodiazepine; C-IV Take 30min to 1h prior to desired sleep, Allocate at least 5 hours after a dose to sleep (T ½ ~1 hour)
134
Cyclobenzaprine
Flexeril Muscle Relaxant May cause drowsiness or dizziness and other anticholinergic side-effects, avoid alcohol use during therapy
135
Metaxalone
Skelaxin Muscle Relaxant Least drowsy muscle relaxant, requires frequent dosing
136
Carisoprodol
Soma Muscle Relaxant; C-IV Drug of abuse, may be scheduled in some states, caution for drowsiness
137
Fentanyl
Duragesic Narcotic Analgesic; C-II Caution for respiratory depression, do not exceed prescribed dose. Avoid exposing patch on the skin to heat as it will increase the delivery of the fentanyl and increase the risk of toxicity, dispose of the used patch by folding over and flushing it, be careful when starting therapy and remember the patch is used for several days normally 72 hours but may see it changed every 48 hours in some patients. Caution in narcotic naive patients as it is 80-100 times more potent analgesic than morphine.
138
Morphine Sulfate
MS Contin Narcotic Analgesic; C-II Risk of CNS and respiratory depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation
139
Oxycodone
Oxycontin Narcotic Analgesic; C-II CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation
140
Oxycodone/APAP
Percocet or Roxicet Narcotic Analgesic; C-II CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation. APAP combination dose will be reduced to no more than 325mg per tablet in the next year. Consider the total daily dose of acetaminophen from all sources.
141
Acetaminophen/ Codeine
Tylenol with Codeine Narcotic Analgesic; C-III CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation. Consider the total daily dose of acetaminophen from all sources.
142
Hydrocodone / chlorpheniramine Polistirex
Tussionex Narcotic Analgesic; C-III CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation, taking with food may decrease some GI upset, Max dose 5mls BID
143
Hydrocodone/Ibuprofen
Vicoprofen Narcotic Analgesic; C-III CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, constipation, taking with food may decrease some GI upset
144
Hydrocodone/APAP
Lortab or Vicodin or Lorcet Narcotic/APAP Analgesic - CIII #1 prescribed drug! CNS depression, avoid alcohol, may cause drowsiness/dizziness, do not operate heavy machinery, avoid concomitant said drugs, constipation. Vicodin reformulated to contain only 300mg of APAP per dose to avoid generic competition and to meet new FDA requirement.
145
Pregabalin
Lyrica Neuropathic Analgesic - CV May cause drowsiness, do not discontinue therapy abruptly. Weight gain, edema and confusion are potential side-effects
146
Varenicline Tartrate
Chantix Nicotinic receptor agonist, Smoking cessation Usually titrated upward. Most effective smoking cessation agent to date ~ 44% at 12 weeks, also watch for night mares and any changes in affect and/or behavior and report them to the prescriber. Side-effects may be dose related.
147
Memantine
Namenda NMDA receptor antagonist; anti-Alzheimer's agent Take in the evening, potential N & D, dizziness and agitation possible. Set realistic expectations. Keep in mind positive statistical significance vs. clinical significance. Take without regard to food
148
Enteric Diclofenac sodium, Diclofenac potassium (non-enteric coated formulation)
Voltaren, Cataflam NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks. Enteric coated diclofenac sodium, slow onset not for PRN pain, greater risk of hepatotoxicity vs. other NSAIDs, use the Cataflam-diclofenac potassium non-enteric coated formulation if for PRN use for pain
149
Etodolac
Lodine (XL) NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks.
150
Indomethacin
Indocin NSAID Take with food, monitor for s/sx of GI bleed.CV and renal risks. Most likely NSAID to cause headache and CNS side-effects.
151
Ketorolac Tromethamine
Toradol NSAID Take with food, monitor for s/sx of GI bleed. Very high risk of GI bleeding limits this drug to 5 days max of therapy. CV and renal risks.
152
Meloxicam
Mobic NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks.
153
Nabumetone
Relafen NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks.
154
Naproxen
Naprosyn, Anaprox/Aleve NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks. Naproxen sodium Aleve/Anaprox fast onset sodium salt vs. regular naproxen-Naprosyn which is slow onset and used for chronic Rx of OA and RA not acute pain relief
155
Piroxicam
Feldene NSAID Take with food, monitor for s/sx of GI bleed, CV and renal risks.
156
Ibuprofen
Motrin or Advil NSAID Take with food, monitor for s/sx of GI bleed. CV and renal risks. Motrin at low doses (IE OTC it is analgesic and antipyretic) but if you need anti-inflammatory effects then you need higher doses 2400 to 3200 mg/day
157
Celecoxib
Celebrex NSAID Cox - II selective Report s/sx of GI bleed, caution for CV risk like all NSAIDS, Not safer for renal function but may be slightly safer for GI bleeding risks
158
Diclofenac/Misoprostol
Arthrotec NSAID/prostaglandin combo Take with food, Misoprostol may decrease GI bleeding risks. CV and renal risks. Avoid in pregnancy. Diarrhea may be a common side effect of the prostaglandin component
159
Tramadol
Ultram, Ultram ER Opioid analgesic May cause drowsiness; avoid alcohol. Drug is scheduled in some states but not by the DEA. Some risk of dependence due to weak opioid receptor agonist activity. Drug also has some serotonin reuptake inhibitor properties; caution against GI effects, serotonin syndrome, increased seizure risk, and drug interactions (especially with SSRIs, SNRIs, 5-HT1 agonists/triptans)
160
Tramadol + acetaminophen
Ultracet Opioid analgesic combo May cause drowsiness; avoid alcohol. Drug is scheduled in some states but not by the DEA. Some risk of dependence due to weak opioid receptor agonist activity. Drug also has some serotonin reuptake inhibitor properties; caution against GI effects, serotonin syndrome, increased seizure risk, and drug interactions (especially with SSRIs, SNRIs, 5-HT1 agonists/triptans). Do not exceed 4g of APAP per day, 3g if frequent alcohol drinker, 2g/day if taking warfarin. New black box warning with acetaminophen due to hepatotoxicity.
161
Hydroxyzine pamoate
Vistaril Antihistamine/antianxiety May cause anticholinergic side-effects.
162
Fluoxetine
Prozac or Sarafem SSRI Antidepressant May cause drowsiness or dizziness, avoid alcohol use during therapy. Prozac longest half-life SSRI (metabolite norfluoxetine T1/2 is ~ 9 days) hence the Prozac weekly dosage form; also most activating of the SSRIs AM dosing not PM and a major inhibitor of CYP 2D6
163
Acetaminophen
Tylenol Pain, antipyretic Limit total daily dose
164
Eszopiclone
Lunesta Sedative Hypnotic Do not take with alcohol, take 30min prior to bed. has a long half-life of ~6 hours and thus an increased risk of morning residual sedation, ~40% of patients complain of a bitter taste the morning after, Need to have at least 8 hours to sleep after a dose and all of these agents can cause complex sleep behaviors (walking, eating, driving, etc.) Do not put yourself in a position where impairment may lead to increased risk of an accident until you know how you respond to the medication.
165
Zolpidem
Ambien (CR) Sedative Hypnotic; C-IV Do not take with alcohol, take 30min prior to bed. Same issues as Lunesta. New lower dosing guidelines for women.
166
Desvenlafaxine
Pristiq SNRI antidepressant Avoid alcohol, do not discontinue abruptly, no added benefit over venlafaxine -recommend generic venlafaxine
167
Duloxetine
Cymbalta SNRI Antidepressant Do not abruptly discontinue therapy. report any changes in affect and or behavior as psychiatric side effects including suicidal ideation is possible
168
Venlafaxine
Effexor (XR) SNRI Antidepressant Avoid alcohol, do not discontinue abruptly, monitor BP
169
Citalopram
Celexa SSRI Antidepressant May cause drowsiness, do not discontinue therapy abruptly. new dosage guidelines of no more than 40 mg/day and avoid in patients with CV disease as it has been shown to increase QT interval (previously recommended for patients with CV disease now only sertraline remains in this category)
170
Escitalopram
Lexapro SSRI Antidepressant May cause drowsiness, do not discontinue therapy abruptly, recommend generic Celexa for cost savings
171
Paroxetine
Paxil (CR) SSRI Antidepressant May cause drowsiness, do not discontinue therapy abruptly. Paxil most likely agent to cause discontinuation syndrome, short half-life and also most tricyclic like of the SSRI’s I.e. sedation, and a major inhibitor of CYP 2D6. New 7.5 mg dose and Brand name drug approved for hot flashes related to menopause.
172
Sertraline
Zoloft SSRI Antidepressant May cause drowsiness or dizziness, avoid alcohol use during therapy. Drug of choice for patients with CV disease and MDD (SAD Heart and ENRICHED Trials, as well as ACC/AHA/APA Guidelines
173
Lidocaine
Lidoderm Patches Topical analgesic Do not apply to broken skin, do not leave patches on for more than 12 hours in a 24 hour period
174
Amitriptyline
Elavil Tricyclic Antidepressant May cause drowsiness or dizziness, avoid alcohol use during therapy. Rarely used for depression and usually used in low doses for off label uses (headaches, pain, neuropathy) as it is a side effect of this agent and it is not well tolerated secondary to anticholinergic effects, risk of overdose causing CV death and arrhythmias, caution for suicidal ideation.
175
Imipramine
Tofranil (PM) Tricyclic Antidepressant May cause drowsiness or dizziness, avoid alcohol use during therapy. Also has significant anticholinergic effects and risk of overdose like Elavil
176
Lithium Carbonate
Eskalith or Lithobid Mood Stabilizer Do not exceed recommended doses, consume 2-3 quarts of water qday. monitor serum levels and watch out for drug interactions with thiazide diuretics which require a dosage reduction of lithium
177
Adapalene
Differin Topical Acne Product Acne may worsen before it improves; using more than recommended increases risk of skin reactions. Use as little product as can cover the face or affected areas with a thin film. Caution against sun exposure and recommend using sunscreen.
178
Clindamycin/Benzoyl Peroxide
Benzaclin Topical Acne Product May cause skin irritation, use a sparing amount. Topical acne products remind patients that their acne may get worse before it gets better and exceeding the recommended doses will increase the risk of severe adverse effects
179
Erythromycin/Benzoyl Peroxide
Benzamycin Topical Acne Product May cause skin irritation, use a sparing amount. Topical acne products remind patients that their acne may get worse before it gets better and exceeding the recommended doses will increase the risk of severe adverse effects
180
Clobetasol
Clobex Topical Corticosteroid Use a sparing amount, avoid application on face and around eyes
181
Mometasone
Elocon Topical Corticosteroid Use a sparing amount, avoid application on face and around eyes
182
Triamcinolone
Kenalog Topical Corticosteroid Use a sparing amount, avoid application around eyes, available in ointment, cream and lotion
183
Pimecrolimus
Elidel Topical skin product Black Box warning due to cancer risk
184
Clotrimazole/Betamethasone Diproprionate
Lotrisone Topical Antifungal/Corticosteroid Use a sparing amount, avoid application on face and around eyes
185
Fluocinonide topical
Lidex, Lidex-E, Vanos Topical Corticosteroid Use a sparing amount, avoid application on face and around eyes
186
Finasteride
Propecia or Proscar 5 alpha reductase inhibitor Pregnant women should not handle, will not regrow hair but will prevent additional hair loss. new data on sexual dysfunction which may not be reversible in men, when used for BPH they are not rapidly effective and may take 6 plus months to shrink and enlarged prostate and produce a reduction in symptoms, probably best when used in combo with an alpha blocker to reduce symptoms and prevent or delay the need for surgical intervention
187
isotretinoin
Accutane or Claravis Acne treatment Must follow REMS system for isotretinoin dispensing and counseling. teratogenic category X, adverse lipid effects especially increased TG and psychiatric effects and as with the topical products acne may get worse before it gets better
188
Testosterone
AndroGel Androgen; C-III Use as directed to upper arm and shoulder and not to genitals. Women and children should avoid contact with this medication; men with BPH may get worse
189
Metformin
Glucophage (XR), Fortamet Antidiabetic - Biguanide Counsel on GI upset, diarrhea and best titration to minimize symptoms, may lead to B12 deficiency related neuropathy
190
Sitagliptin, Sit+Metformin
Januvia, Janumet (XR) Take without regard to food, risk of pancreatitis
191
Saxagliptin
Onglyza Antidiabetic - Dipeptidyl peptidase IV inhibitor Take without regard to food, risk of pancreatitis, concomitant use of CYP3A4 Inh - use 2.5mg instead of 5 mg QD.
192
Glimepiride
Amaryl Antidiabetic - Sulfonylurea Take with breakfast, avoid alcohol use, counsel on hypoglycemic risk
193
Glipizide
Glucotrol (XL) Antidiabetic - Sulfonylurea May cause hypoglycemia due to active metabolites
194
Glyburide, Glyburide/Metformin
Micronase, Glucovance Antidiabetic - Sulfonylurea Take with breakfast, avoid alcohol use. Has an active metabolite which is renally eliminated and thus increased risk of hypoglycemia and weight gain as patients age, may also increase CV events and no longer a recommended agent by the ADA
195
Pioglitazone
Actos Antidiabetic - Thiazolidinedione Take without regard to meals, increased risk of fractures, macular edema, heart failure, weight gain and edema as well as bladder CA in men.
196
Exenatide, Exenatide weekly
Byetta, Bydureon Antidiabetic Glucagon-Like Peptide-1 Receptor Agonist Counsel on pen injection technique. Nausea and vomiting tend to be dose related and transient start with 5 mcg daily dose and after a month increase to 10 mcg dose, watch for signs of pancreatitis and can be dosed 60 min or less before meals twice a day
197
Liraglutide
Victoza Antidiabetic Glucagon-Like Peptide-1 Receptor Agonist Counsel on pen injection technique. Nausea and vomiting tend to be dose related and transient, watch for signs of pancreatitis. Box warning - Rodent studies - risk of thyroid C-cell tumors.
198
Alendronate
Fosamax Bisphosphonate Osteoporosis Agent Take on an empty stomach with a full glass of water, must sit or stand for 30 minutes following the dose, osteonecrosis of jaw and atypical fractures
199
Ibandronate
Boniva Bisphosphonate Osteoporosis Agent Take on an empty stomach with a full glass of water, must sit or stand for 60 minutes following the dose. osteonecrosis of jaw and atypical fractures
200
Risedronate, delayed release enteric coated risedronate
Actonel, Atelvia Bisphosphonate Osteoporosis Agent Take on an empty stomach with a full glass of water, must sit or stand for 30-60 minutes following the dose. Atelvia is enteric coated formulation which should be taken after breakfast but not available as generic. osteonecrosis of jaw and atypical fractures
201
Estrogen/Methyltestosterone
Estratest (HS) Combination Hormone CV, thromboembolic caution
202
Estradiol/Norethindrone
Combipatch Estrogen and Progestin Combination Stable at room temperature for 3 months
203
Conjugated Estrogens
Premarin Estrogen hormone May take with food to decrease GI symptoms
204
Estradiol
Climara, Estrace Estrogen Hormone CV, thromboembolic caution
205
Raloxifene
Evista Estrogen receptor modulator, Post-menopausal Osteoporosis CV risk and thromboembolic black box warnings, may inc TGs, myalgia. May cause or worsen hot flashes
206
Conjugated Estrogens with medroxyprogesterone
Prempro or Premphase Estrogen-Progestin hormone combo increased risk of CV and DVT as well as dementia with long term therapy, report any abnormal vaginal bleeding
207
Colchicine
Colcrys Gout - Inflammatory Mediator Long-term therapy requires blood work. no more than 3 tablets for an acute attack with similar efficacy to 8 tablets but with much less risk of GI toxicity
208
Allopurinol
Zyloprim Gout - Xanthine Oxidase Inhibitor Consume large amounts of fluids to prevent kidney stone formation. start with 100 mg QD after an acute gout attack has subsided and gradually increase the dose at no more than weekly interval to about 300 mg QD to reduce the risk of mobilization gout, may also add low dose colchicine 1-2 tabs per day for prevention of mobilization gout, D/C at first signs of a rash
209
Febuxostat
Uloric Gout - Xanthine Oxidase Inhibitor Same as allopurinol but may be safe in patients with a history of adverse skin reactions to allopurinol.
210
Medroxyprogesterone Acetate
Provera Hormone/Progestin May take with food to decrease GI symptoms, preg cat: X, may lead to uterine bleeding irregularities, long term use may decrease bone mineral density
211
Insulin - regular
Humulin R Insulin - Fast Acting counsel on injection technique and hypoglycemia, take 15-30 min prior to meal
212
Insulin - NPH
Humulin N Insulin - Intermediate Acting counsel on injection technique and hypoglycemia
213
Insulin Detemir
Levemir Insulin - Intermediate-Long acting cannot be mixed with another insulin
214
Insulin Glargine
Lantus Insulin - Long Acting cannot be mixed with another insulin, May have an increase in injection site pain/rxn
215
Insulin Aspart
Novolog Insulin - Rapid Acting Take immediately before meals, counsel on injection technique and hypoglycemia
216
Insulin Lispro
Humalog Insulin - Rapid Acting Take immediately before meals, counsel on injection technique and hypoglycemia
217
Insulin Glulisine
Apidra Insulin - Rapid Acting Take immediately before meals, counsel on injection technique and hypoglycemia
218
Ethinyl Estradiol/ Drospirenone
Yasmin, Ocella, Yaz Oral contraceptive Take everyday - counsel on missed dose protocol, caution with antibiotics. new warnings about increased risk of VTEs especially in older women and those who smoke ; risk of hyperkalemia
219
Ethinyl Estradiol / Desogestrel
Kariva, Ortho-Cept, Mircette, Desogen or Apri Oral contraceptive Take everyday - counsel on missed dose protocol, caution with antibiotics. new warnings about increased risk of VTEs especially in older women and those who smoke ; risk of hyperkalemia
220
Ethinyl Estradiol / Levonorgestrel
Aviane, Alesse Oral contraceptive Take everyday - counsel on missed dose protocol, caution with antibiotics. new warnings about increased risk of VTEs especially in older women and those who smoke ; risk of hyperkalemia
221
Norethindrone/Ethinyl Estradiol,Fe+
Loestrin FE Oral contraceptive Take at same time everyday, counsel on missed dose protocol. Caution with antibiotics, smoking
222
Norgestimate & Ethinyl Estradiol
TriNessa, Tri-Sprintec Oral contraceptive Take at same time everyday, counsel on missed dose protocol. Caution with antibiotics, smoking
223
Norgestimate/Ethinyl Estradiol
Ortho Tri-Cyclen (Lo) Oral contraceptive Take at same time everyday, counsel on missed dose protocol. Caution with antibiotics, smoking
224
Ethinyl Estradiol / Norelgestromin
Ortho Evra Patch contraceptive Each patch should remain in place for 7 days, CV risk, smoking risk
225
Insulin 70% NPH/ 30 % Regular
Novolin 70/30, Humulin 70/30 Pre-Mixed insulin counsel on injection technique and hypoglycemia, 1st # is percent of intermediate release insulin and second is fast acting
226
Insulin 70% protamine/ 30 % rapid acting
Novalog Mix 70/30, Humalog Mix 75/25 Pre-Mixed insulin counsel on injection technique and hypoglycemia, 1st # is percent of intermediate release insulin and second is rapid acting
227
Medroxyprogesterone
Depo-Provera Progestin Contraceptive May cause weight gain, preg cat: X, may lead to uterine bleeding irregularities, long term use may decrease bone mineral density
228
Prednisone
Deltasone Steroid Anti-inflammatory Take with food, may cause agitation, insomnia
229
Methylprednisolone
Medrol Steroid anti-inflammatory/allergy Take with food, may cause agitation, insomnia
230
Desiccated thyroid
Armour thyroid Thyroid Hormone Take on an empty stomach in the morning
231
Levothyroxine
Synthroid or Levoxyl Thyroid Hormone (synthetic T4) Narrow Therapeutic Index Drug: Take on an empty stomach in the morning with full glass of water at least 30 minutes prior to food (Do not take close to Calcium), Stay on specific brand or generic due to bioavailability issues, TSH monitoring (many dosages available from 25mcg to 300 mcg for fine tuning), adverse drug reactions early on often due to too high of dosing (med induced hyperthyroidism - heat intolerance and sweating, frequent bowel movements, restlessness, tachycardias, hair loss). Pregnancy Cat A:may need to increase dose in pregnancy, drug instable in light and humidity. Levothyroxine FDA Orange Book 4 sub categories of AB ratings (i.e. AB1, AB2,AB3 and AB4) so be careful when switching between brands and generic manufacturers stay within the same AB subclass; takes 4 weeks to reach new steady state levels and TSH may lag another 2-3 weeks
232
Estradiol
Vivelle-Dot, Estraderm Topical estrogen patch Counsel on twice weekly patch application. Note: Climara is once-weekly patch
233
Ethinyl Estradiol / Etonogestrel
NuvaRing Vaginal contraceptive Counsel on vaginal application, 3 weeks in, 1 week off
234
Estradiol
Vagifem Vaginal estrogen Counsel on vaginal tablet use with Vagifem
235
Dicyclomine
Bentyl Anticholinergic for cramping/irritable bowel May cause dry mouth, dizziness. Avoid alcohol use.
236
Hyoscyamine
Levsin/Levbid/Levsinex Anticholinergic for cramping/irritable bowel Take before meals. May experience dizziness, blurred vision, constipation.
237
Loperamide
Imodium Antidiarrheal May cause drowsiness, contact MD if diarrhea persists longer than 48 hours
238
Diphenoxylate/Atropine
Lomotil Antidiarrheal; C-V Do not exceed prescribed dose, anticholinergic side-effects possible
239
Promethazine
Phenergan Antihistamine - Nausea/Vomiting treatment May cause anticholinergic side-effects.
240
Lubiprostone
Amitiza Chloride Channel Activator Take with food to decrease nausea
241
Orlistat
Xenical Fat absorption inhibitor Caution regarding uncontrollable oily bowel movements especially after high fat meal, patient should take supplemental fat soluble vitamins at least 2 hrs prior to orlistat dose
242
Famotidine
Pepcid H 2 Antihistamine Do not exceed 14 days of OTC therapy unless directed by MD, report severe abdominal pain/discomfort to MD
243
Ranitidine
Zantac H 2 Antihistamine Do not exceed 14 days of OTC therapy unless directed by MD, report severe abdominal pain/discomfort to MD
244
Polyethylene Glycol
Miralax, Glycolax Laxative Safe for daily use, one heaping teaspoon dissolved in 8 oz of water once daily as needed
245
Metoclopramide
Reglan Promotility-Antiemetic Take 30 minutes prior to meal, avoid use with alcohol, associated with extrapyramidal symptoms and depression, caution in elderly
246
Esomeprazole
Nexium Proton Pump Inhibitor Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
247
Lansoprazole
Prevacid Proton Pump Inhibitor Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
248
Omeprazole
Prilosec Proton Pump Inhibitor Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
249
Pantoprazole
Protonix Proton Pump Inhibitor Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
250
Rabeprazole
Aciphex Proton Pump Inhibitor Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
251
Omeprazole/sodium bicarbonate
Zegerid Proton Pump Inhibitor/Antacid combo Take 30- 60 min prior to a significant meal. all of these meds are pro-drugs which need to be absorbed in that state and are activated within the parietal cell when the patient stimulates them to secrete acid by eating. They all also have a short half-life of 1-2 hours. Risks include C Diff diarrhea, pneumonia, fractures and low serum magnesium levels in addition to B12 deficiency
252
Dutasteride
Avodart BPH - 5 alpha reductase inhibitor Capsules should not be handled by women, takes time for shrinkage of prostate and symptom relief
253
Tamsulosin
Flomax BPH - selective alpha blocker Take 30min after the same meal every day. May cause dizziness.
254
Alfuzosin
Uroxatral BPH - selective alpha blocker Take prior to bedtime to avoid orthostatic hypotensive effects
255
Vardenafil
Levitra Erectile dysfunction - vasodilator Report erections lasting longer than 4 hours to ER, avoid nitroglycerin use
256
Sildenafil
Viagra Erectile dysfunction - Vasodilator Report erections lasting longer than 4 hours to ER, avoid nitroglycerin use
257
Tadalafil
Cialis Erectile dysfunction - Vasodilator Report erections lasting longer than 4 hours to ER, avoid nitroglycerin use
258
Oxybutynin
Ditropan (XL) Urinary Incontinence - Anticholinergic May cause dry mouth, dizziness. Avoid alcohol use.
259
Tolterodine
Detrol (LA) Urinary Incontinence - Anticholinergic May cause dry mouth, dizziness. Avoid alcohol use.
260
Darifenacin
Enablex Urinary Incontinence - Anticholinergic May cause dry mouth, dizziness. Avoid alcohol use.
261
Phenazopyridine
Pyridium Urinary Tract Analgesic Urine will change to orange-red color …not a cause for alarm, used only for symptom relief and not a cure
262
cholecalciferol
Calcitriol Vitamin D supplement Take with food to decrease GI problems
263
Brimonidine
Alphagan P Agent for Glaucoma
264
Latanaprost
Xalatan Agent for Glaucoma
265
Timolol
Timoptic (XE) Agent for Glaucoma
266
Travoprost
Travatan Agent for Glaucoma
267
Brimonidine/Timolol
Combigan Alpha II agonist/beta blocker/ antiglaucoma
268
Olopatadine
Pataday or Patanol Antiallergy (ophthalmic)
269
Tobramycin/Dexamethasone
Tobradex Antibiotic/anti-inflammatory (Ophthalmic)
270
Moxifloxacin
Vigamox Antibiotic/Ophthalmic
271
Cyclosporine
Restasis Calcineurin inhibitor (Ophthalmic) nvert vial several times prior to use to create uniform emulsion. Used every 12 hours.
272
Dorzolamide/Timolol
Cosopt Carbonic anhydrase inhibitor/beta blocker/antiglaucoma
273
Gatifloxacin
Zymar Fluoroquinolone (Ophthalmic)
274
Bimatoprost
Lumigan prostaglandin analog for glaucoma treatment
275
Neomycin/polymyxin/hydrocortisone
Cortisporin Otic Otic Antibiotic
276
Ciprofloxacin/Dexamethasone, Ciprofloxacin/Hydrocortisone
Ciprodex, Cipro HC Otic Antibiotic/Corticosteroid
277
Azelastine
Astelin Allergic Rhinitis - Topical H1 antagonist Prime 4x upon assembly, 2x if left unused for 3 days or more
278
Budesonide Nasal Spray
Rhinocort Aqua Allergic rhinitis -Nasal Steroid May cause taste distortion, effects seen after several days of therapy, May cause nasal irritation, bleeding
279
Fluticasone
Flonase Allergic rhinitis -Nasal Steroid May cause dysgeusia (taste distortion), effects seen after several days of therapy, May cause nasal irritation, bleeding
280
Mometasone
Nasonex Allergic rhinitis -Nasal Steroid May cause dysgeusia (taste distortion), effects seen after several days of therapy, May cause nasal irritation, bleeding
281
Montelukast
Singulair Anti -asthmatic - Leukotriene inhibitor chewable tablet contains phenylalanine
282
Albuterol
Proair HFA or Ventolin HFA or Proventil HFA Anti- asthmatic - short-acting beta-2 agonist Available in both MDI and nebulizer soln. Counsel on appropriate device use and prn rescue dosing. May also be use for prophylaxis for exercise-induce asthma. May cause jitteriness, nervousness, tachycardia and decrease effectiveness of beta blockers.
283
levalbuterol
Xopenex (HFA) Anti-asthmatic - short-acting beta-2 agonist counsel on appropriate MDI use and prn rescue dosing
284
Budesonide Inhalation Suspension
Pulmicort Respules, Flexhaler Anti-asthmatic - Steroid Some effects seen after first 2 days of therapy, maximum effect seen within first 2 weeks of therapy, not to be used for rescue
285
Fluticasone
Flovent Anti-asthmatic - Steroid Some effects seen after first 2 days of therapy, maximum effect seen within first 2 weeks of therapy, not to be used for rescue
286
Fluticasone/Salmeterol
Advair Antiasthmatic - Steroid /LA B2 agonist Antiasthmatic - Controller Diskus: Do not shake after activating, counsel on device technique, not to be used for rescue
287
Albuterol/Ipratropium
Respimat or Duoneb Antiasthmatic/COPD Combo Bronchodilator/Anticholinergic see albuterol and ipratropium counseling points, Combivent will no longer be available. Respimat is a new device with a counter - pt counseling required.
288
Tiotropium
Spiriva HandiHaler Anticholinergic bronchodilator for COPD counsel on device technique and once-daily use
289
Ipratropium Bromide
Atrovent Anticholinergic antibrochospasm and antisecretory Shake well, hold breath for 10 sec after actuation, wait 1 minute for 2nd inhalation, usually very little systemic side-effects because of poor absorption
290
Cetirizine
Zyrtec Antihistamine, 2nd generation H1 May cause drowsiness, dizziness or dry mouth. Available in syrup and tablets
291
Desloratadine
Clarinex Antihistamine, 2nd generation H1 May cause drowsiness, dizziness or dry mouth
292
Loratidine
Claritin Antihistamine, 2nd generation H1 May cause drowsiness, dizziness or dry mouth
293
Fexofenadine (PSE)
Allegra (D) Antihistamine, 2nd generation H1 (+Decongestant) May cause drowsiness, do not take with fruit juices. PSE may cause insomnia, take D products in AM
294
Guaifenesin
Mucinex (D, DM) Expectorant (+/- decongestant, antitussive) Take with large glass of water, BID dosing, PSE may cause insomnia, PSE contraindicated in patients with CV risk, hypertension, DM drug interactions
295
Guaifenesin & Codeine
Cheratussin AC Expectorant/Antitussive combo - CV Take with water, codeine side-effect possible
296
herpes zoster vaccine
Zostavax Herpes Zoster (shingles virus) Vaccine CDC 60 yrs and above, FDA approved for 50 and above. Decreases risk of shingles and complications, such as postherpetic neuralgia. Not a substitute for varicella vaccine. Separate from Pneumovaz by 4 weeks
297
Human papillomavirus vaccine
Gardasil, Cervarix Human papillomavirus vaccine (HPV) Potentially prevents cancer. Given in 3 doses over 6 months, Gardasil approved for males also
298
influenza virus vaccine
Afluria or Fluvirin or Fluzone Influenza Virus Vaccine Once yearly dosing generally recommended before Halloween. Now, a variety of dosage forms available.
299
pneumococcal polysaccharide vaccine
Pneumovax Streptococcus Pneumoniae Bacterial Vaccine Once (or twice) life-time dosing in high risk patients. Pneumovax can now also be given along with Prevnar 13 in older patients with significant risks as of 6-21-12 ACIP Meeting
300
Tetanus, Diphtheria, Pertussis Vaccine
Tdap Tetanus, Diphtheria, Pertussis booster dose after DTaP series in childhood, can replace a Td booster, preferred administration 11-12 years of age.