Top 300 Flashcards
(300 cards)
Metronidazole
Flagyl, Flagyl ER
Antibacterial, Antiprotozoal
Finish course as prescribed. Avoid alcohol during therapy and for 2 days after. May discolor urine reddish-brown.
Fluconazole
Diflucan
Antifungal
Finish course as prescribed. May cause headache and GI upset. CYP interactions: strongly inhibits 2C9, 2C19 (ex. Clopidogrel, warfarin and phenytoin); moderately inhibits 3A4. May prolong QT interval.
Ketoconazole
Nizoral
Antifungal
Available topically and orally. Tablets should be taken with food. Drug is absorbed best in acidic conditions; avoid antacids, PPI’s and H2 blockers for 2 hours before and after administration. Major CYP 3A4 drug interactions. Topical formulations are flammable. Potential for hepatotoxicity.
Nystatin
Mycostatin, Nystop
Antifungal
Available in many different dosage forms (topical, oral, suspension, powder) and some combination products. Suspension can be dosed as “swish and spit” for oral candidiasis or “swish and swallow” for esophageal candidiasis.
Terbinafine
Lamisil
Antifungal
Finish course as prescribed. Topical formulation available OTC and is most common use.
Acyclovir
Zovirax
Antiviral against HSV
Available topically and orally. Avoid intercourse during herpes outbreaks. Dose and duration depends on indication. CNS side-effects especially in elderly and renal impairment. Interacts with herpes zoster vaccine. Stay well hydrated.
Valacyclovir
Valtrex
Antiviral against HSV
Avoid intercourse during herpes outbreaks. Dose and duration depends on indication. CNS side-effects especially in elderly and renal impairment. Interacts with herpes zoster vaccine. Stay well hydrated.
Cephalexin
Keflex
Cephalosporin antibiotic, 1st generation
Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.
Cefuroxime axetil
Ceftin
Cephalosporin antibiotic, 2nd generation
Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.
Cefdinir
Omnicef
Cephalosporin antibiotic, 3rd generation
Finish course as prescribed. May cause GI upset. Hypersensitivity reactions may occur if allergic to penicillin and/or other cephalosporins. May decrease absorption of oral contraceptives.
Ciprofloxacin
Cipro (XR)
Fluoroquinolone antibiotic
Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic and otic suspensions.
Levofloxacin
Levaquin
Fluoroquinolone antibiotic
Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic suspension.
Moxifloxacin
Avelox
Fluoroquinolone antibiotic
Finish course as prescribed. Monitor glucose. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). May cause sun sensitivity and CNS side-effects. FDA requires assessment of risk of QTc prolongation. Black box warning for tendonitis/tendon rupture. Available orally and in ophthalmic solution (Vigamox, Moxeza).
Azithromycin
Zithromax, Zmax, Azasite
Macrolide antibiotic
Finish course as prescribed. No CYP 3A4 inhibition. QT prolongation possible. Opthalmic solution, Azasite, is refrigerated.
Clarithromycin
Biaxin (XL)
Macrolide antibiotic
Finish course as prescribed. May impart metallic taste. Inhibits CYP 3A4. QT prolongation possible.
Clindamycin
Cleocin, Cleocin T, Evoclin, Clindagel
Available in many dosage forms (oral, topical, vaginal suppository, powder for suspension) and combination products. Oral therapy may cause C. diff-associated severe diarrhea. Suspension has horrible taste, little flavoring options available.
Nitrofurantoin
Macrobid, Macrodantin, Furadantin
Take with food to enhance absorption. May cause peripheral neuropathy or pulmonary fibrosis. Shake suspension thoroughly.
Amoxicillin
Amoxil
Penicillin antibiotic
Finish course as prescribed. May cause GI upset; take with food. Hypersensitivity reactions possible. May decrease efficacy of oral contraceptives. Secondary vaginal yeast infection may develop. Shake susp well and keep refrigerated, note exp date after reconstitution
Amoxicillin + Clavulanate
Augmentin, Augmentin XR
Penicillin antibiotic
Finish course as prescribed. May cause GI upset; take with food. More likely to have diarrhea b/c of clavulanate- maintain hydration. Clavulanic acid doses vary among formulations; double-check if using alternate formulation to achieve prescribed dose (ex. 400mg-57mg/5ml suspension cannot be substituted for 600mg-42.9mg/5ml suspension). Shake susp well and keep refrigerated, note exp date after reconstitution
Penicillin V Potassium
Veetids, Pen-Vee K
Penicillin antibiotic
Finish course as prescribed. May cause GI upset; take with food. C. diff-associated diarrhea may develop. Hypersensitivity reactions possible.
Sulfamethoxazole + Trimethoprim
Bactrim, Bactrim DS, Septra, Septra DS
Sulfonamide antibacterial
Finish course as prescribed. Take with plenty of water. Increases sensitivity to sunlight. Increased risk of hypoglycemia if taken with other sulfonylureas. Severe life-threatening skin reactions possible.
Doxycycline
Vibramycin, Doryx, Adoxa, Monodox, Oracea, Periostat
Tetracycline antibiotic
May increase sensitivity to sunlight. Do not take within 2 hours of consuming foods or other products containing di- or trivalent cations (ex. milk, calcium antacids, multivitamins and supplements). Hyclate and monohydrate salts not interchangeable.
Metronidazole
Metrogel, Metrogel-Vaginal, Metrocream, Metrolotion
Topical antibiotic
Use condoms during vaginal therapy. Some drug is absorbed systemically; avoid alcohol consumption during therapy and for 2 days after. Also used topically on the face for rosacea.
Mupirocin
Bactroban
Topical antibiotic
Used most in hospital to reduce the risk of MRSA infection from carriers