Topic 14 pt 2: Population Genetics

Question 1

Two alleles for PTC tasting in humans

Answer 1

PAV -> tasting = normal/WT taste receptor
AVI -> nontasting = recessive

Question 2

If one allele is very high and all others near zero? If most alleles are present in a similar frequency?

Answer 2

Most individuals will be homozygous

Heterozygotes will be near 50%

Question 3

As the frequency of the recessive allele decreases…

Answer 3

The relative proportion of recessive alleles found in hets increases (most ‘a’ found in hets)

Question 4

Slide 6**

Answer 4

HWE mathematical model

Question 5

Calculation of heterozygosity observed and expected

Answer 5

Observed = n hets / n total

Expected = 1 - (p^2 + q^2)
-> minus all homos

Question 6

What is expected heterozygosity? Measure is used for…

Answer 6

Probability that an individual in a pop will be a het at a locus
Used to compare levels of genetic variation between loci or populations

Question 7

Slides 11 to 14

Answer 7

Very confusing