Topic 2: Principles Flashcards
(14 cards)
science that deals with the study of the immune system.
Immunology
deals with study of
antigen-antibody reactions, detected
by various principles and techniques;
it is diagnostic in application
Serology
deals
with the study of blood group systems
as they apply to blood transfusion and
tissue transplantation; it is the
underlying science of blood banking.
Immunohematology
foreign substance which
when introduced to a host, will
stimulate an immune response.
Antigen
2 properties of antigen
Specific reactivity and Immunogenicity
Characteristics of an antigen
Foreign to the host
Sufficient molecular size
Chemical complexity
Structural stability
Blood group antigens are widely distributed throughout:
Tissues
RBC
WBC
Platelets
Body fluids
Blood group antigens adsorbed on the red cells
Lewis
ABH
If blood group antigens is
found in the secretions, they are
called
Blood group substances
Most blood group antigens are
Glycoproteins
Majority of highly immunogenic blood group antigens are
Proteins
Carrier of traits, found in chromosomes
Genes
integral structural
component of the RBC membrane; if
these antigens are missing, the
membrane becomes defective and
results in hemolytic anemia
Rh antigens
project from the surface
of the red blood cell membrane.
ABO antigens