Topic 4.1 Communicable diseases, prevention and the immune system Flashcards

(36 cards)

1
Q

What is a pathogen?

A

A pathogen is a microorganism that causes disease by infecting a host

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2
Q

Name the four types of pathogens

A

Bacteria

Viruses

Protoctista

Fungi

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3
Q

How do bacteria cause disease?

A

Bacteria cause disease by producing toxins and damaging host tissues

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4
Q

What is tuberculosis and how is it transmitted?

A

Tuberculosis is a bacterial infection affecting the lungs, transmitted via airborne droplets

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5
Q

Describe the symptoms and transmission of bacterial meningitis

A

Bacterial meningitis causes headache, fever, stiff neck, and light sensitivity.
It spreads via respiratory droplets and close contact

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6
Q

What does Ring Rot affect and what are its symptoms?

A

Ring Rot affects tomatoes, potatoes, and aubergines.
It causes leaf wilting, yellowing, and ring decay in tubers

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7
Q

How do viruses reproduce and damage host cells?

A

They reproduce by hijacking host cells and forcing them to produce more viruses, leading to cell lysis

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8
Q

What is Tobacco Mosaic Virus (TMV) and how does it affect plants?

A

TMV causes mosaic leaf patterns, stunted growth, and reduced yield.
It spreads via plant contact and contaminated tools.

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8
Q

How is HIV/AIDS transmitted and what does it affect?

A

HIV/AIDS spreads through bodily fluids and destroy white blood cells, weakening the immune system.

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9
Q

How is malaria transmitted and what are the symptoms?

A

Malaria is caused by protoctista transmitted by female mosquitoes.
Symptoms include fever, chills, and fatigue.

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10
Q

Describe Black Sigatoka and its method of transmission

A

A fungal disease in bananas causes dark leaf streaks and reduced yield.
It spreads through airborne droplets

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11
Q

Why do plants rely on chemical and physical defences against pathogens?

A

Because plants cannot move, they depend on internal mechanisms to detect and defend against infection

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12
Q

What is the role of saponins in plant defence?

A

Saponins are antifungal compounds that disrupt fungal cell membranes

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13
Q

How does callose deposition protect plants?

A

Callose is deposited in cell walls and sieve plates to block pathogen movement

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14
Q

What is lignification and how does it prevent infection?

A

Lignification involves adding lignin to cell walls, making them tougher and impermeable to pathogens

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15
Q

What is necrosis in plant defence?

A

Necrosis is deliberate cell death around infection sites to limit pathogen access to water and nutrients

16
Q

How does the skin act as a primary defence against pathogens?

A

The skin acts as a physical barrier and secretes sebum, which inhibits microbial growth

17
Q

Describe the role of platelets in blood clotting

A

Platelets activate upon injury, forming a clot by converting fibrinogen to insoluble fibrin, which traps blood cells

18
Q

What are histamines and their function in inflammation?

A

Histamines cause vasodilation and increase capillary permeability to promote localised heat and swelling

19
Q

How does mucous membranes defend against pathogens?

A

They produce mucus that traps pathogens; cilia waft the mucus to be expelled or swallowed

20
Q

What is opsonin and what is its role in phagocytosis?

A

Opsonins are molecules that bind to pathogens to enhance recognition and engulfment by phagocytes.

21
Q

What is the difference between neutrophils and macrophages?

A

Neutrophils are short-lived and respond quickly; macrophages present antigens on their surface after engulfing pathogens.

22
Q

What happens in clonal selection of T cells?

A

A T helper cell binds to an APC presenting a complimentary antigen, activating the T cell

23
Q

What is the function of T killer cells?

A

T killer cells destroy infected host cells by releasing perforin

24
Name three functions of antibodies
Neutralisation, agglutination, and opsonisation
25
How are B cells activated in the immune response?
B cells bind to antigens and are activated by interleukins from T helper cells, leading to clonal expansion
26
What are agglutinins and how do they work?
Agglutinins are antibodies that cause pathogens to clump together, making phagocytosis more efficient
27
What is the difference between active and passive immunity?
Active immunity involves memory cell production and is long-lasting; passive immunity is short-term and involves antibody transfer
28
Give an example of natural passive immunity
Antibodies passed from mother to baby through breast milk or the placenta
29
What type of immunity is produced after vaccination?
Artificial active immunity
30
What causes autoimmune diseases?
The immune system attacks self-antigens, mistaking them for foreign pathogens
31
What body part is affected by type 1 diabetes and how is it treated?
The insulin-secreting cells of the pancreas are treated with insulin injection, pancreas transplants, or immunosuppressants
32
Why is biodiversity important for medicine development?
Many undiscovered species may provide compounds with medicinal potential
33
How did the discovery of penicillin revolutionise medicine?
It provided an effective way to treat bacterial infection, reducing morality rates
34
What is antibiotic resistance, and why is it a concern?
It is when bacteria evolve to survive antibiotics, making infections harder to treat and increasing medical costs
35
What are the two possible sources of medicine?
Microorganisms and plants