Topic 5 - Homeostasis and Response - Homeostasis in action Flashcards
(20 cards)
How is the body temperature kept constant?
- body has to balance amount of energy gained and lost to keep core body temperature constant
- this relies on thermoregulatory centre in the hypothalamus of your brain
- contains receptors sensitive to temperature of blood flowing through brain
How does negative feedback control body temperature?
- temperature receptors detect that core body temperature too high
- thermoregulatory centre acts as a coordination centre - receives information from temperature receptors
- effectors e.g. sweat glands produce response to counteract change (vice versa)
What happens when you are too hot?
- sweat produced by sweat glands - evaporates from skin - transfers energy to environment
- blood vessels supplying the surface skin capillaries dilate so more blood flows closer to surface of skin
- this is vasodilation - helps trasnsfer energy from skin to environment
What happens when you are too cold?
- hairs stand up to trap insulating layer of air
- no sweat produced
- blood vessels supplying the surface skin capillaries constrict to close off skins bloody supply - vasoconstriction
- shiver - needs respiration - transfers some energy to warm body
Why does CO2 need to be removed from the body?
- dissolved CO2 produces an acidic solution
- affects working of all enzymes in the body
Why does urea need to be removed from the body?
is poisonous - if levels build up in body - could cause extensive damage to cells
Urea and filtration?
- proteins and their amino acids can’t be stored by body - excess amino acids converted into fats + carbohydrates - can be stored
- occurs in liver and involves process called deamination
- ammonia produced as waste product from this process
- ammonia is toxic - converted into urea in liver- urea then transported to kidneys where it is filtered out of blood and excreted from body in urine
Ions and filtration?
- ions such as sodium taken into body in food - absorbed into the blood
- if ion content of body is wrong - could upset balance between ions and water - too much or too little water drawn into cells by osmosis
- having wrong amount of water can damage cells or mean they don’t work as well as normal
- some ions are lost in sweat - this amount is not regulated - right balance of ions in body must be maintained by kidneys - right amount of ions reabsorbed into blood after filtration - rest is removed from body in urine
Water and filtration?
- body has to constantly balance water coming in against water going out
- we lose water from skin in sweat and from lungs when breathing out
- can’t control how much we lose in those ways - amount of water is balanced by amount we consume and amount removed by kidneys in urine
Very simply, what do the kidneys do?
act as filters to clean the blood
What is the kidneys function?
- kidneys make urine by removing waste products from your blood
- substances are filtered out of blood as it passes through the kidneys - called filtration
- useful substances like glucose, some ions and right amount of water are absorbed back into blood
- processes called selective reabsorption
How is the concentration of urine controlled?
- concentration of urine controlled by hormone called anti-diuretic hormone (ADH) - is released into bloodstream by pituitary gland
- brain monitors water content of blood - instructs pituitary gland to release ADH into blood according to how much is needed
- whole process is controlled by negative feedback.
ADH four marker?
- ADH released by pituitary gland when the body water content too low
- makes kidney tubules more permeable to water
- means more water is reabsorbed from the tubules back into the bloodstream
- as a result, a smaller volume of more concentrated urine is produced
What happens if the kidneys don’t work properly?
- waste products build up in blood - you lose your ability to control levels of ions and water in your body
- eventually this results in death
How can people who have kidney failure be helped?
- can be kept alive by having dialysis treatment where machines do the job of the kidneys
- could have a kidney transplant.
How does dialysis work?
- dialysis has to be done regularly to keep the concentrations of dissolved substances in the blood at normal levels + to remove waste substances
- in a dialysis machine - person’s blood flows between partially permeable membranes surrounded by dialysis fluid - permeable to things like ions and waste substances - not big molecules like proteins (just like the membranes from the kidney)
- dialysis fluid has same concentration of dissolved ions and glucose as healthy blood
- useful dissolved ions and glucose won’t be lost from blood during dialysis
- only waste substances and excess ions and water diffuse across the barrier
Disadvantages of dialysis?
- many patients with kidney failure have to have a dialyis session 3 times a week - each session takes 3-4 hours
- may cause blood clots or infections
- not pleasant - expensive for the NHS to run
How do kidney transplants work?
- currently - kidney transplants are only cure for kidney failure
- healthy kidneys usually transplanted from people who have died suddenly
- person who died has to be on organ donor register or carry donor card
- kidneys can also be transplanted from people who are still alive - small risk to person donating the kidney
Disadvantages of kidney transplants?
- risk donor kidney can be rejected by patient’s immune system
- antigens on cell surface of donor organ can trigger your antibodies in immune system to attack the foreign antigens
- patient treated with immunosuppressants to prevent this
Compare dialysis and kidney transplant?
transplants cheaper in long run than dialysis - people with a kidney transplant can live a more free life