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DRUG LIST - PHARMACOLOGY > TOPIC LIST B. > Flashcards

TOPIC LIST B. Flashcards

1
Q

B) 1. Cholinergic transmission and its presynaptic modification.

A

botulinum toxin, vesamicol, hemicholinium

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2
Q

B) 2. Adrenergic transmission and its presynaptic modification

A

Metyrosine (antihypertensive effect): inhibit conversion of Tyrosime to DOPA

Carbidopa, Benserazide: inhibit conversion of DOPA to Dopamine

Reserpine (outdated antihypertensive): inhibit the transport of Dopamine into the vesicle

Guanethidine, Debrisoquine and Bretylium: inhibit the Ca2+ influx and thus the release of NE from the vesicle to the synaptic cleft

L-DOPA (levodopa): used in Parkinsons to increase Dopamine synthesis

Bupropion - inhibits reuptake: used as an anti-depressant that can also be used to help quit smoking

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3
Q

B) 3. Cholinomimetics

A

carbachol, pilocarpine, neostigmine, pyridostigmine, rivastigmine, edrophonium

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4
Q

B) 4. Muscarinic receptor blocking drugs

A

atropine, scopolamine, butyl-scopolamine, ipratropium, procyclidine, solifenacin, cyclopentolate, tiotropium, oxybutinine

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5
Q

B) 5. Catecholamines

A

epinephrine, norepinephrine, dopamine, isoprenalin, dobutamine

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6
Q

B) 6. Indirect sympathomimetics. Selective α2-agonists and drugs acting on the imidazoline receptors

A

ephedrine, phenylephrine, clonidin, rilmenidine, methyldopa, oxymetazoline

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7
Q

B) 7. α-receptor antagonists

A

prazosin, doxazosin, tamsulosin, urapidil, carvedilol, phentolamine

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8
Q

B) 8. β-receptor antagonists

A

propranolol, pindolol, carvedilol, timolol, sotalol, metoprolol, bisoprolol, nebivolol, esmolol

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9
Q

B) 9. Centrally acting skeletal muscle relaxants (spasmolytics). Dantrolene. Botulinum toxin

A

baclofen, tolperisone, diazepam, tizanidine, dantrolene, botulinum toxin

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10
Q

B) 10. Skeletal muscle relaxants acting on the neuromuscular junction

A

atracurium, cisatracurium, mivacurium, pipecuronium, rocuronium, succynylcholine (suxamethonium)

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11
Q

B) 11. Selective β2-stimulants and other bronchodilators. Pharmacotherapy of bronchial asthma and COPD.

A

salbutamol, terbutaline, fenoterol, salmeterol, formoterol, ipratropium, tiotropium, theophyllin

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12
Q

B) 12. Antiinflammatory agents used in bronchial asthma. Antitussive agents and expectorants

A

prednisolone, methylprednisolon, fluticazone, budesonide, montelukast, omalizumab, codein, butamirate, prenoxdiazine, acetylcystein, bromhexin

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13
Q

B) 13. Drugs used for the treatment of peripheral vascular diseases. Therapy of migraine

A

vinpocetin, nicergolin, cilostazol, pentoxifyllin, Ca-dobesilate, sumatriptan, galkanezumab, cinnarizin, propranolol, verapamil, carbamazepine, valproate, imipramine

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14
Q

B) 14. Drugs used for treatment of heart failure I: Drugs decreasing the load on the heart. Drugs of acute cardiac failure. Pharmacotherapy of chronic heart failure.

A

see ACE-inhibitors, diuretics, beta-blockers, etc.

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15
Q

B) 15. Drugs used for treatment of heart failure II: Positive inotropic agents. Pharmacotherapy of acute heart
failure

A

digoxin, digitoxin, milrinone, levosimendan, dobutamine

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16
Q

B) 16. Antiarrhytmic agents

A

lidocaine, propafenone, esmolol, amiodarone, sotalol verapamil, adenozine, digoxin, Mg2+

17
Q

B) 17. Drugs used for the treatment of hypertension I: Classification of antihypertensive agents and their mechanisms of action. Pharmacotherapy of hypertension.

A

B18-B19 and sympatholytics, diuretics

Hydrochlorothiazide
Furosemide

Clonidine
Methyldopa
Guanadrel
Prazosin - Doxazosin - Tamsulosin
Propranolol
Metoprolol - Bisoprolol - Nebivolol
Labetalol - Carvedilol
Dihydropiridine (+its under drugs)
Diltiazem
Verapamil
Hydralazine
Minoxidil
Fenoldopam

Etc

18
Q

B) 18. Drugs used for the treatment of hypertension II: Ca2+-channel blockers and other vasodilators

A

amlodipine, felodipine, nifedipine, nimodipine, verapamil, dihydralazine, bosentan, sildenafil

19
Q

B) 19. Drugs used for the treatment of hypertension III: Drugs acting on the renin-angiotensin-aldosterone
system

A

enalapril, perindopril, ramipril, losartan, valsartan, valsartan + sacubitril, irbesartan, spironolactone, eplerenon, captopril

20
Q

B) 20. Drugs used for treatment of angina pectoris. Pharmacotherapy of ischemic heart disease.

A

nitroglicerin, isosorbid-mononitrate, trimetazidine, ivabradin, beta-bockers, and Ca-channel blockers

21
Q

B) 21. Agents used in dyslipidaemias.

A

simvastatin, atorvastatin, rosuvastatin, ezetimib, fenofibrate, colesevelam

22
Q

B) 22. Potassium excreting (wasting) diuretics

A

acetazolamide, hydrochlorothiazide, indapamide, furosemide, etacrynic acid

23
Q

B) 23. Potassium sparing diuretics, ADH antagonists, osmotic diuretics

A

spironolactone, eplerenone, amiloride, tolvaptan, mannitol, glycerol

24
Q

B) 24. Histamine and antihistamines.

A

promethazine, diphenhydramine, (levo)cetirizine, (des)loratadine, fexofenadin, dimetindene

DRUG LIST - PHARMACOLOGY (2 decks)

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