Topical glucocorticoids Flashcards

1
Q

Triamcinolone acetonide/Fluocinonide/Betamethasone

A

acetonide or ester forms have better potency due to high lipophilicity

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2
Q

Clobetasol propionate/Halobetasol propionate/Halcinonide

A

contain 21-chloro group

enhances topical anti-inflammatory activity as it is more lipophilic

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3
Q

Fluticasone propionate/Mometasone furoate

A

high lipophilicity and high binding affinity

low solubility (contains microcrystals)

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