topics 2

Question 1

2.13 local control of circulation. Characteristics of vascular smooth muscle. Myogenic, humoral, hormonal and neural control mechanism

Answer 1

Local: autoregulation, metabollic control, endothelium mediated ( NO, PGI2)
Humoral: vasodilators (his, ser, NO)/ Vasoconstrictors( endo, angio 2)
Hormonal: vasodilators ( epi, ANP , PGI2 )/ vasoconstrictors (NE, AG 2, ADH, his, ser ,endothelin)
Neural: symp increases

Question 2

2.14 Coronary circulation and its control

Answer 2

Q=250ml/min
VO2= 30 ml/min
AVDO2= 120ml O2/L

Metabolic regulation with different factors
Autoregulation
Neurohumoral reg: symp effects , metabolites , NO