Tox- Exam 2 Corssword

Question 1

PCP uncouples oxidative phosphorylation and blocks or decreases _____

Answer 1

PCP uncouples phosphorylation and blocks or decreases ATP

Question 2

This organ is primarily responsible for removing excess copper from the bloodstream

Answer 2

The Liver is primarily responsible for removing excess copper from the bloodstream

Question 3

A high rumen pH favors the nonionized state of _______, enhancing systemic absorption

Answer 3

A high rumen pH favors the nonionized state of ammonia, enhancing systemic absorption.

Question 4

T/F:

Floridia, California, Oregon and Nevada have soil that is poor in Molybdenum

Answer 4

False:

Flordia, Claifornia, Oregon and Nevada have soil Rich in molybdenum

Question 5

Metaldehyde toxicity typically causes CNS _____

Answer 5

Metaldehyde toxcitiy typicall causes CNS Excitation

Question 6

You can increase renal excretion of 2,4-D by _____ the urine pH

Answer 6

You can increase renal excretion of 2,4-D by increasing the urine pH

Question 7

Which chealating agent is similar but more hydrophilic than dimercaprol (BAL)?

Answer 7

Succimer is a chelating agent that is similar but more hydrophilic than dimercapol (BAL)

Question 8

A potential source of exposure for PCP is ____ treated with it, which may be licked by the animal.

Answer 8

A potential source of exposure for PCP is wood treated with it, which may be licked by the animal

Question 9

Iron toxicity; Free Iron causes and

Answer 9

Iron toxicity: Free iron causes peroxidation and free radicals

Question 10

Which animal group is most susceptible to inorganic arsenical toxicity?

Answer 10

Herbivores are most susceptible to inorganic aresnical toxicity.

Question 11

Which Chelator is used for Iron?

Answer 11

Deferoxamine is the chelator used for Iron (Fe)

Question 12

High sodium levels in the brain lead to because of the action of osmosis

Answer 12

High sodium levels in the brain lead to edema because of the action of osmosis.

Question 13

“Blackberry Jam” Spleen is assoicated with what toxin?

Answer 13

Black berry jam” spleen is assoicated with Copper toxicosis.

Question 14

Iron is bound to in the blood

Answer 14

Iron is bound to Transferrin in the blood

Question 15

Both Fomepizole and ethanol are inhibitors of alcohol dehydrogenase

Answer 15

Both Fomepizole and Ethanol are competative inhibitors of alcohol dehydrogenase

Question 16

Depigmentation of the hair around the can be a sign of molybdenum toxicosis.

Answer 16

Depigmentation of the Hair around the eyes can be a sign of molybdenum toxicosis.

Question 17

Paraquat can be easured in up to 48 hours post-exposure

Answer 17

Paraquat can be measured in urine up to 48 hours post-exposure

Question 18

causes mainly pulmonary signs which must be delayed by several days.

Answer 18

Paraquat causes mainly pulmonary signs which may be delayed by several days.

Question 19

Which toxin causes mainly pulmonary signs which may be delayed by several days?

Answer 19

Paraquat mainly causes pulmonary signs that may be delayed by several days

Question 20

Which toxin is 99% bound to RBCs in the bloodstream?

Answer 20

Lead is 99% bound to RBCs in the bloodstream

Question 21

Bright red blood and mucous membranes are characteristic of which toxin?

Answer 21

Cyanide:

Bright red blood/Mucous membranes

Question 22

Nitrite oxidizes ferrous iron on the heme group to ferric, resulting in

Answer 22

Nitrite oxidizes ferrous iron on the heme group to ferric, resulting in M__ethemoglobin

Question 23

Deficiency in what predisposes an animal to copper toxicity?

Answer 23

Deficiency in molybdenum predisposes animals to copper toxicity

Question 24

promotes the release of zinc which is why prolonged time in the stomach increases toxicity

Answer 24

Acid promotes the release of zinc which is why prolonged time in the stomach increases toxicity.

Question 25

T/F North and South Dakota, Wyoming, montana, Nebraska, Kansas, Utah, Colorado and New Mexico have soil **Rich** in selenium

Answer 25

**True**; North and South Dakota, Wyoming, montana, Nebraska, Kansas, Utah, Colorado and New Mexico have soil **Rich​** in selenium

Question 26

Which species is most susceptible to ionophore toxicity? Hint it likes to die

Answer 26

The **Horse** is most susceptible to inophore toxocity

Question 27

Sodium picrate paper exposed to cyanide from rumen contents will turn from to in a sealed container

Answer 27

Sodium picrate paper exposed to cyanide from rumen contents will turn from **_yellow**_ to _**brick-red_** in a sealed container

Question 28

Riddle time: I go good with food and I enter the brain by passive diffusion and I leave by active transport **What am I?**

Answer 28

**Sodium**: Enters the brain by passive diffusion and leaves by active transport

Question 29

What is treated by phenobarbital which may also enhance metabolism and excretion by inducing microsomal enzymes?

Answer 29

**Metaldehyde** is treated by Phenobarbital. Phenobarbital may also enhance metabolism and excretion by inducing microsomal enzymes

Question 30

While Arsenilic acid is used as a growth promoter in swine. is used in poultry as a growth promotor

Answer 30

While Arsenilic acid is used as a growth promoter in swine. **Roxarsone** is used in poultry as a growth promotor

Question 31

Tiamulin, Chloramphenicol, erythromycin, and sulfonamides are examples of drugs that increase the toxicity of what drug?

Answer 31

Tiamulin, Chloramphenicol, erythromycin, and sulfonamides are examples of drugs that increase the toxicity of **Ionophores**

Question 32

Locoweed, aster and corn are plants that accumulate which mineral if it is rich in the soil?

Answer 32

Locoweed, aster and corn are plants that accumulate **Selenium** when it is rich in the soil

Question 33

Very young animals (3-6 weeks) are tolerant to dietary urea/NPN

Answer 33

Very young animals (3-6 weeks) are **More** tolerant to dietary urea/NPN

Question 34

Which toxin binds to albumin and beta-2-macroglobulin in blood?

Answer 34

**Zinc** binds to albumin and beta-2-macroglobulin in blood