toxicities and specific antidotes

Question 1

antidote for acetaminophen

Answer 1

N-acetylcysteine (replenishes glutathione0

Question 2

antidote for organophosphates

Answer 2

atropine > pralidoxime

Question 3

antidote for amphetamines

Answer 3

NH4Cl to acidify the urine

Question 4

antidote for antimuscarinics or anticholinergics

Answer 4

physostigmine

Question 5

antidote for benzodiazepines

Answer 5

flumazenil

Question 6

antidote for beta blockers

Answer 6

glucagon

Question 7

antidote for carbon monoxide poisoning

Answer 7

100% O2, hyperbaric oxygen

Question 8

antidote for copper or arsenic

Answer 8

penicillamine

Question 9

antidote for cyanide (almond breath)

Answer 9

nitrite + thiosulfate or hydroxcobalamin

Question 10

antidote for digitalis

Answer 10

anti-dig Fab fragments

Question 11

antidote for heparin

Answer 11

protamine sulfate

Question 12

antidote for iron

Answer 12

DeFeroxamine or deferasirox

Question 13

antidote for lead

Answer 13

EDTA, dimercaprol, succimer, penicillamine

Question 14

antidote for mercury or arsenic or gold

Answer 14

dimercaprol or succimer

Question 15

antidote for methanol or ethylene glycol

Answer 15

fomepizole or dialysis

Question 16

antidote for methemagolbin

Answer 16

methylene blue or vitamin C

Question 17

antidote for TCAs

Answer 17

sodium bicarb

Question 18

antidote for warfarin

Answer 18

Vitamin K for delayed effect, fresh frozen plasma for immediate

Question 19

tPA/streptokinase urokinase e

Answer 19

aminocaproic acid

Question 20

when do we not give beta blockers

Answer 20

avoid in cocaine users and pheochromocytoma.

Question 21

what does cholinesterase inhibitor poisoning look like

Answer 21

DUMBBELSS

diarrhea, urination, miosis bronchospasm, bradycardia, excitation of skeletal muscle, lacrimation, sweating, salivation.

Question 22

what is the most common cause cholinesterase inhibitor poisoning

Answer 22

organophosphates

Question 23

what is the antidote to cholinesterase inhibitor poisoning or organophosphates

Answer 23

atropine and or pralidoxime.

Question 24

what does atropine toxicity look like

Answer 24

HOT as a hare
DRY as a bone
RED as a beat 
BLIND as a bat 
MAD as a hatter 
increased body temperature, rapid pulse, dry mouth, flushed skin, cycloplegia, constipation, disorientation

Question 25

what can atropine do in the elderly

Answer 25

cause acute angle closure glaucoma. due to mydriasis.

Question 26

what is the antidote for atropine tox

Answer 26

physostigmine