Toxicology Flashcards

1
Q

Abiotic Degradation

A

The breakdown of non-living things, photolysis and hydrolysis

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2
Q

Absorption

A

The act of being taken up or in, especially the passage of a compound through a surface of the body or into the body, systemic circulation

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3
Q

Ames Test

A

test for mutagens using bacteria

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4
Q

Anthropogenic

A

man-made toxins

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5
Q

Aryl hydrocarbon Receptor

A

Ligand-activated transcription factor present in many cells which links environmental chemical stimuli with adaptive responses, such as detoxification

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6
Q

Bioaccumulation

A

tendency of a compound to accumulate in the bodies of organisms from the environment

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7
Q

Bioassay

A

a measurement of the effect of a chemical

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8
Q

Bioavailability

A

the fraction of a substance available for absorption into a biological system

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9
Q

Bioconcentration Factor

A

ratio of the concentration of the chemical in the organism and water at equilibrium

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10
Q

Biomagnification

A

a food chain phenomenon, where by a substance is found at higher concentrations at higher levels of the food chain

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11
Q

Biomarker

A

a biological event that is indicative of exposure to a toxicant or a class of toxin

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12
Q

Exposure

A

used to asses the amount of chemical that is present within the body

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13
Q

Effect

A

used to asses the biological effect to a chemical, measuring how the organism respornded

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14
Q

Susceptibility

A

used to predict the likely impact of exposure to a chemical, usually by assessing a genetic or metabolic predisposition to how the organism will respond to exposure

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15
Q

Bioremediation

A

natural processes that help eliminate toxins

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16
Q

Carbamate Insecticides

A

developed to address DDT’s problem, not very toxic to vertebrates and break down quickly

17
Q

Dioxin-like chemicals

A

indoles, flavones, benzoflavones, imidazoles, and pyridines, these compounds are metabolized rapidly, but continuous intake from food may cause similar receptor activation as the background levels of dioxins

18
Q

Henrys Law

A

Vapor pressure/water solubility (higher KH = more toxin in air)

19
Q

Hydrolysis

A

the reaction of water with the chemical addition of a water molecule to the chemical, often double bonds or causes the release of part of the chemical-replaced by oxygen from water rate of hydrolysis is often affected by temp, light and PH

19
Q

Hyperaccumulation

A

the process of uptake, translocation and accumulation of the heavy metals at concentrations higher than the surrounding in different parts of the plant

19
Q

Botanicals

A

metabolites that occur in nature like rotenone and black leaf 40

20
Q

Organophosphate Insecticides

A

one type of pesticide that works by damaging an enzyme in the body called acetylcholinesterase

21
Q

Persistence

A

slow to break down

22
Q

photolysis

A

light can be absorbed by some chemical bonds absorbed light increase energy in bond and may break the bond

23
Q

Direct photolysis

A

direct effect on the chemical

24
Q

Indirect photlysis

A

light-absorbed species and it transfer energy to another chemical - transferred energy causes degradation of the second chemical

25
Q

phytodegredation

A

the alteration or breakdown of materials by light

26
Q

phytoremediation

A

the use of plants and associated soil microbes to reduce the concentration or toxic effects of contaminants in the environment