Toxicology Flashcards

(28 cards)

1
Q

Abiotic Degradation

A

The breakdown of non-living things, photolysis and hydrolysis

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2
Q

Absorption

A

The act of being taken up or in, especially the passage of a compound through a surface of the body or into the body, systemic circulation

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3
Q

Ames Test

A

test for mutagens using bacteria

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4
Q

Anthropogenic

A

man-made toxins

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5
Q

Aryl hydrocarbon Receptor

A

Ligand-activated transcription factor present in many cells which links environmental chemical stimuli with adaptive responses, such as detoxification

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6
Q

Bioaccumulation

A

tendency of a compound to accumulate in the bodies of organisms from the environment

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7
Q

Bioassay

A

a measurement of the effect of a chemical

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8
Q

Bioavailability

A

the fraction of a substance available for absorption into a biological system

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9
Q

Bioconcentration Factor

A

ratio of the concentration of the chemical in the organism and water at equilibrium

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10
Q

Biomagnification

A

a food chain phenomenon, where by a substance is found at higher concentrations at higher levels of the food chain

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11
Q

Biomarker

A

a biological event that is indicative of exposure to a toxicant or a class of toxin

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12
Q

Exposure

A

used to asses the amount of chemical that is present within the body

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13
Q

Effect

A

used to asses the biological effect to a chemical, measuring how the organism respornded

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14
Q

Susceptibility

A

used to predict the likely impact of exposure to a chemical, usually by assessing a genetic or metabolic predisposition to how the organism will respond to exposure

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15
Q

Bioremediation

A

natural processes that help eliminate toxins

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16
Q

Carbamate Insecticides

A

developed to address DDT’s problem, not very toxic to vertebrates and break down quickly

17
Q

Dioxin-like chemicals

A

indoles, flavones, benzoflavones, imidazoles, and pyridines, these compounds are metabolized rapidly, but continuous intake from food may cause similar receptor activation as the background levels of dioxins

18
Q

Henrys Law

A

Vapor pressure/water solubility (higher KH = more toxin in air)

19
Q

Hydrolysis

A

the reaction of water with the chemical addition of a water molecule to the chemical, often double bonds or causes the release of part of the chemical-replaced by oxygen from water rate of hydrolysis is often affected by temp, light and PH

19
Q

Hyperaccumulation

A

the process of uptake, translocation and accumulation of the heavy metals at concentrations higher than the surrounding in different parts of the plant

19
Q

Botanicals

A

metabolites that occur in nature like rotenone and black leaf 40

20
Q

Organophosphate Insecticides

A

one type of pesticide that works by damaging an enzyme in the body called acetylcholinesterase

21
Q

Persistence

A

slow to break down

22
Q

photolysis

A

light can be absorbed by some chemical bonds absorbed light increase energy in bond and may break the bond

23
Direct photolysis
direct effect on the chemical
24
Indirect photlysis
light-absorbed species and it transfer energy to another chemical - transferred energy causes degradation of the second chemical
25
phytodegredation
the alteration or breakdown of materials by light
26
phytoremediation
the use of plants and associated soil microbes to reduce the concentration or toxic effects of contaminants in the environment