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Flashcards in Toxicology Deck (39)
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1

What is the antidote for acetaminophen toxicity?

NAC

2

What is the antidote for anticholinergic toxicity?

physostigmine

3

What is the antidote for arsenic, lead, and mercury toxicity?

dimercaprol, succimer, d-penicillamine

4

What is the antidote for benzodiazepine toxicity?

flumazenil

5

What is the antidote for a black widow spider bite?

latrodectus antivenin

6

What is the antidote for beta-blocker toxicity?

glucagon, insulin and glucose

7

What is the antidote for CCB toxicity?

calcium, glucagon, insulin and glucose

8

What is the antidote for cyanide toxicity?

hydroxycobalamin

9

What is the antidote for cyanide, hydrogen sulfide toxicity?

Na thiosulfate and nitrate
hydroxycobalamin

10

What is the antidote for digitalis glycoside toxicity?

digoxin-specific Fab

11

What is the antidote for ethylene glycol toxicity?

fomepizole, thiamine

12

What is the antidote for hydrofluouric acid toxicity?

calcium gluconate

13

What is the antidote for iron toxicity?

deferoxamine

14

What is the antidote for lead toxicity?

DMSA, EDTA

15

What is the antidote for methanol toxicity?

ethanol, fomepizole

16

What is the antidote for isoniazid, hydrazine, and monomethylhydrazine toxicity?

pyridoxine

17

What is the antidote for methemoglobin-forming agent toxicity?

methylene blue

18

What is the antidote for opioid toxicity?

nalfemene, naloxone

19

What is the antidote for organophosphate and carbamate toxicity?

atropine, protopam

20

What is the antidote for a rattlesnake bite?

CroFab antivenin

21

What is the antidote for serotonin syndrome?

Cyproheptadine

22

What is the antidote for sulfonurea toxicity?

Octreotide

23

What is the antidote for TCA toxicity?

Bicarbonate

24

What is the antidote for valproic acid toxicity?

Carnitine

25

What criteria do you need to look at the establish causation for toxicants?

The Hill Criteria

26

How do most intoxications occur?

accidents!

27

What do you do for the vast majority of patients in the ED?

Decontaminate only

28

The culprit usually reflects _______

accessibility

29

Examples of drugs that are toxic to children even in small amounts?

antimalarials, antidysrhythmics, benzocaine, B blockers, CCBs, camphor, clonidine, lomotil, lindane, methyl salicylate, opioids, theophylline, TCAs

30

What are the rules of general patient management?

A - airway, B - breathing, C - circulation, DEFG - dont ever forget glucose! D - disability / Coma scale, G - get a basic set of observations

31

How does charcoal (SDAC) work?

Eliminated in feces, absorbs drugs -- must protect airways!!

32

What is the time window for charcoal?

within 1 hour

33

What is the syrup of Ipecac? What is the concern with it?

It induces emesis but it will not be of use after 30 minutes; ALSO being looked at for cardiotoxicities

34

What is a lavage?

Instilling several liters of H20 and then suctioning out; keep airways patent

35

What is whole bowel irrigation?

Useful for enteric coating or sustained release; goes below stomach area into small and large intestine

36

When is hemodialysis useful? What would it work on?

Useful for water soluble, low molecular weight, low plasma protein binding toxins; ex: methanol, ethylene glycol, salicylates, lithium, sotalol

37

What is hemoperfusion? What would it work on?

Passage of blood through charcoal filter and removes high plasma protein binding toxins; ex: carbamazepine, phenobarbitol, theophylline, phenytoin

38

Memorize slide 28

Do it

39

What is the most toxic B blocker?

propanolol