Trachea, bronchial tree and lungs Flashcards

(47 cards)

1
Q

What are the conducting portions of the respiratory system?

A
  • Nose, nasal cavity, paranasal sinuses
  • Pharynx (nasopharynx, oropharynx, laryngopharynx)
  • Larynx
  • Trachea
  • Bronchi, bronchial tree
  • Terminal bronchioles
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2
Q

What are the respiratory portions of the respiratory system?

A
  • Respiratory bronchioles
  • Alveoli (ducts and sacs)
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3
Q

Describe the Trachea

A
  • Fibrous and cartilaginous tubeconducting air from larynx to bronchi
  • 10-11 cm long, ~2.5cm diameter, from C6 to T4/5 vertebral levels
  • Has “c shaped” cartilage rings to maintain patency
  • Posteriorly, smooth muscle called trachealis which joins each end of the rings, controls diameter
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4
Q

Describe the Carina

A

Point where the trachea divides into two main bronchi T4/5 level

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5
Q

What structures are posterior to the Trachea?

A
  • Oesophagus
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6
Q

What structures are anterior to the Trachea?

A
  • Thyroid gland isthmus
  • Brachiocephalic trunk, Left brachiocephalic vein
  • Cardiac plexus nerves (sympathetic and parasympathetic)
  • Tracheobronchial lymph nodes
  • Manubrium
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7
Q

What surface landmark marks the bifurcation of the Trachea?

A

Sternal Notch

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8
Q

What structures pass laterally to the Trachea?

A
  • Thyroid gland lobes
  • Parathyroid glands
  • Left and Right Common carotid arteries
  • Aortic arch and left subclavian artery
  • Azygous arch and right Vagus nerve
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9
Q

What structures lie posterolaterally to the Trachea?

A
  • Left and right recurrent laryngeal nerves
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10
Q

Describe the arterial supply of the Trachea

A
  • Inferior thyroid artery
  • Bronchial artery
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11
Q

Describe the venous drainage of the Trachea

A
  • Inferior thyroid vein
  • Bronchial veins
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12
Q

Describe the lymphatic drainage of the Trachea

A
  • Pre and Paratracheal nodes
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13
Q

Describe the nerve supply of the Trachea

A

Pulmonary plexus

  • Parasympathetic from Vagus nerve
  • Sympathetic from Sympathetic trunk
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14
Q

What is the sympathetic system’s effect on the Trachea?

A

Dilation

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15
Q

What is the parasympathetic system’s effect on the Trachea?

A

Constriction

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16
Q

Describe the structure of the Bronchi

A

Continuation of the Trachea
- Complete cartilage rings
- Smooth muscle

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17
Q

How many secondary bronchi are there?

A

3 Right
2 Left

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18
Q

How many Bronchial Arteries are there?

A

1 Right
2 Left

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19
Q

Describe Bronchioles

A
  • Serial divisions of conducting bronchioles, down to 20-25 generations
  • As number increases size individually decreases but total surface area increases
  • Becomes respiratory bronchioles –> alveolar ducts –> alveolar sacs
20
Q

Describe Alveoli

A
  • Single cell thick sac
  • Surrounded by vasculature
  • Large surface area - efficient for gas exchange
21
Q

Describe the histology of the Trachea

A
  • Cartilage - ossifies with age
  • Respiratory epithelium - ciliated pseudostratified columnar
  • Trachealis muscle
22
Q

Describe the histology of the bronchioles

A
  • No cartilage
  • Smooth muscle
  • Respiratory epithelium - ciliated pseudostratified columnar
23
Q

What are club cells?

A
  • Non-ciliated cuboidal epithelial cells found in terminal bronchioles
  • Produce protective secretions
24
Q

Describe the walls of the Alveoli

A

Pneumocytes
* Type I - thin to allow for gas exchange
* Type II - produce surfactant

25
What are the functions of the Lungs?
* Gas exchange * pH balance * Prostaglandin synthesis * Metabolic functions - angiotensin I to angiotensin II
26
Describe the lobes and fissures of the left lung
Superior Lobe Oblique Fissure Inferior Lobe
27
Describe the lobes and fissures of the right lung
Superior Lobe Horizontal Fissure Middle Lobe Oblique Fissure Inferior Lobe
28
Where do the vasculature and airways enter the lung?
Root of the Lung in the Hilum
29
Describe Lung Segments
Right and Left: * Superior lobe Apical Posterior Anterior * Inferior lobe Superior (apical) Anterior basal Posterior Basal Medial basal Lateral basal Right only: * Lateral and medial segments of middle lobe Left only: * Superior lingular and inferior lingular of superior lobe
30
Describe the clinical significance of Lung Segments
Separated by Septa * Infection typically confined to one segment * Can be resected as one unit * Each have own arterial supply from pulmonary artery
31
What is the Root of the Lung
Connection of the Lung to the Mediastinum Contains: * Main bronchus * Pulmonary Arteries and Veins * Bronchial Arteries and Veins * Lymph Nodes and Vessels
32
Describe the Arterial Supply of the Lung
Bronchial Arteries * 2 Left - supplied by Aorta * 1 Right - supplied by 3rd Intercostal Artery Pulmonary Arteries * From pulmonary trunk * Most superior structure in Hilum
33
Describe the Venous Drainage of the Lungs
Bronchial Veins * Drain to Azygos on the Right, Hemiazygos on the Left * Can re-enter pulmonary circulation Pulmonary Veins * Two per side (Superior and Inferior)
34
Describe the Pulmonary Plexus
Divided into Anterior and Posterior parts * Relative to the trachea and bronchi Supplied from * Vagus parasympathetically * Sympathetic Trunk Supplies lungs and visceral pleura
35
Describe the parasypathetic system's effect on the lungs
Bronchoconstriction, vasodilation and secretomotor
36
Describe the sympathetic system's effect on the lungs
Bronchodilation and vasoconstriction
37
Describe the Lymphatic drainage of the Lungs
* Subpleural plexus * Intrapulmonary Nodes * Hilar Nodes * Tracheobronchial Nodes * Paratracheal Nodes * Bronchomediastinal trunks
38
Describe the clinical considerations of Asthma
Commonest lung condition - >8 million people UK Airway diameter reduced by inflamation Different types * Allergic * Non-allergic * Occupational Salbutamol treatment * β2 receptor agonist - relaxes bronchial muscle
39
Descrobe the clinical considerations of COPD
Common - biggest risk factor is smoking Causes * Mucus hypersecretion * Alveolar desctruction * Emphysema * Chronic bronchitis
40
Describe the clinical considerations of Lung Cancer
Smoking is the biggest risk factor * Bronchial carcinoma (95% of primary tumours) * Common site for metastatic tumours - via lymphatic system Asbestos * Mesothelioma Pancoast Tumour * Tumour in the Apical lobe * Can cause nerve compression Poor prognosis
41
Describe the clinical considerations of pneumothorax
Air in pleural cavity - "Collapsed Lung" Causes * Spontaneous in tall, thin males * Penetrating chest injury * Lung damage * Higher risk in certain syndromes
42
Describe the clinical considerations of Pneumonia
Infective * Bacterial * Viral * Fungal Can affect one or multiple lobes * Lobar pneumonia More likely with underlying health conditions or frailty Lying supine is a risk factor
43
Describe the clinical considerations of Cystic Fibrosis
Commonest genetically transmitted disease * Autosomal recessive * 1 in 2000 Mucous too thick due to abnormal ionic composition * Malfunctioning chloride transporter
44
Describe the clinical considerations of Foreign Body Aspiration
Items have tendency to the right bronchus * Not always detectable by X-ray Bronchoscopy to visualise/retrieve
45
Describe the clinical considerations of Pulmonary Embolism
Blockage occurs in pulmonary artery * Thrombus from lower limb * Fat * Air * Tumour Risk factors * Immobilisation * Recent surgery * Malignancy * Paralysis * Smoking * Obesity
46
Describe a Tracheostomy
Incision into trachea via 2nd and 3rd tracheal rings * Non-emergency procedure * Likely to be long term * Consider position of the inferior thyroid veins
47
Describe a Bronchoscopy
Camera inserted to visualise the lungs * Performed under sedation * Can occur alongside device to remove foreign body or take biopsy