Transfusion Reactions Flashcards
(27 cards)
What blood group is the universal donor?
O-
What blood group is the universal receiver?
AB is the universal Blood receiver
What group is the universal plasma doner?
AB
Which blood group is the universal plasma receiver
O
What are the features of a mild blood transfusion reaction?
Fever and urticaria
What is the 1st line management for a MILd transfusion reaction
Paracetamol and antihistamine
What are the features of a major transfusion reaction?
Fever urticaria Respiratory distress Hypotension Tachycardia Oliguria Collapse Bleeding
What is the management protocol of a major transfusion reaction?
Stop the transfusion Check the right match Consider anaphylaxis TRALI and bacterial infection Treat appropriately
What is a TACO?
Transfusion Associated Circulatory Overload
In how many blood transfusions does this occur?
1% transfusions
How are you going to manage a TACO?
Slow the rate of the transfusion and give Iv diuretic + O2
What does AHTR stand for?
Acute haemolytic transfusion reaction
What are the 2 types of AHTR
Immediate = acute complement mediated lysis
delayed lysis
What are the features of immediate and delayed AHTR
Immediate = shock, high fever and renal failure Delayed = anaemia and jaundice 7-10 days post-transfusion
what is the risk of a viral infection form a transfusion?
1 in 1mil
What is the management of an infection from a blood transfusion?
IV antibiotics
Fluids, O2 and
Notify the blood transfusion unit
What is the key diagnostic test for AHTR?
DAGT positive
What is the management of AHTR?
o2, IV fluids, diuretics, inonotropes, dialysis and notify the blood transfusion service
What does TRALI stand for?
Transfusion related acute lung injury
What is the management of TRALI?
Respiratory support, O2, IV fluids and NOTIFY
What is Piron Disease?
This is a variant of CJD that is transmissible by blood transfusion from sheep
What are the management steps for Piron disease?
Reduce the transmission! “ UK plasma not used for fractionation
Imported FFP for all pts born after 1996
What is haemolytic disease of the newborn?
Where the mother is Rh-ve but the child is Rh +tve and then the antigens crosses the placenta to the mother Mum makes anti-RhD IgG which crosses placenta, messes it all up innit
What are the 2 presenting symptoms of HDofN?
Anemia and jaundice?
